ChemicalBook >> CAS DataBase List >>4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride structure

CAS No.: 28783-41-7

Chemical Name:: 4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride

Synonyms: 4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE HYDROCHLORIDE;Tetrahydrothienopyridine Hydrochloride;4,5,6,7-TETRAHYDROTHIENO[3,2,C] PYRIDINE HCL;Clopidogrel-7;2-c]pyridine HCl;7-Tetrahydrothieno[3;Pragrace Impurity 23;Zidovudine impurity F;Clopidogrel Impurity 56;Clopidogrel Impurities6

CBNumber:: CB6122076

Molecular Formula:: C7H9NS

Molecular Weight:: 139.22

MDL Number:: MFCD05861485

MOL File:: 28783-41-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:03:16

Product description	Number	Pack Size	Price
4,5,6,7-Tetrahydrothieno[3,2-c]pyridine Hydrochloride >98.0%(HPLC)(N)	T2770	5g	$19
4,5,6,7-Tetrahydrothieno[3,2-c]pyridine Hydrochloride >98.0%(HPLC)(N)	T2770	25g	$42
4,5,6,7-Tetrahydrothieno[3,2-c]pyridine Hydrochloride	TRC-T295750-2.5G	2.5g	$101
4,5,6,7-Tetrahydrothieno[3,2-c]pyridine Hydrochloride	TRC-T295750-1G	1g	$76
4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE HCL 96%	69672	4*25G	$23
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4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride Properties

Melting point	212-215°C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO, Methanol, Water
form	Solid
color	White to Off-White
Major Application	pharmaceutical
InChI	InChI=1S/C7H9NS/c1-3-8-5-6-2-4-9-7(1)6/h2,4,8H,1,3,5H2
InChIKey	OGUWOLDNYOTRBO-UHFFFAOYSA-N
SMILES	C12CNCCC=1SC=C2
CAS DataBase Reference	28783-41-7(CAS DataBase Reference)
FDA UNII	E0HB70DQ7N
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Risk Statements

36/37/38

Safety Statements

26-36/37/39-37

RIDADR

UN2811

WGK Germany

WGK 3

HazardClass

IRRITANT

HS Code

29333990

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 3 Oral

REACH Registrations

Active

NFPA 704

	1
2		0

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride price More Price(87)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	T2770	4,5,6,7-Tetrahydrothieno[3,2-c]pyridine Hydrochloride >98.0%(HPLC)(N)	28783-41-7	5g	$19	2026-04-30	Buy
TCI Chemical	T2770	4,5,6,7-Tetrahydrothieno[3,2-c]pyridine Hydrochloride >98.0%(HPLC)(N)	28783-41-7	25g	$42	2026-04-30	Buy
TRC	TRC-T295750-2.5G	4,5,6,7-Tetrahydrothieno[3,2-c]pyridine Hydrochloride	28783-41-7	2.5g	$101	2026-06-03	Buy
TRC	TRC-T295750-1G	4,5,6,7-Tetrahydrothieno[3,2-c]pyridine Hydrochloride	28783-41-7	1g	$76	2026-06-03	Buy
AstaTech	69672	4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE HCL 96%	28783-41-7	4*25G	$23	2026-04-30	Buy

Product number	Packaging	Price	Buy
T2770	5g	$19	Buy
T2770	25g	$42	Buy
TRC-T295750-2.5G	2.5g	$101	Buy
TRC-T295750-1G	1g	$76	Buy
69672	4*25G	$23	Buy

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

An intemediate of Clopidogrel and Prasugrel.

Synthesis

30433-91-1

50-00-0

28783-41-7

Example 5: Preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride In a 2-liter four-necked flask equipped with a thermometer and a mechanical stirrer, 2-thiophene ethylamine (100 g, 0.79 mol) was added. The reaction was dissolved in dichloromethane (600 ml) at 25°C (±5°C) and stirred for 5 to 10 minutes. Subsequently, paraformaldehyde (26.4 g, 0.88 mole) was added to the reaction system and the reaction was subjected to azeotropic reflux at 40 to 45°C for 4 to 6 hours. Upon completion of the reaction, the system was cooled to room temperature and a N,N-dimethylformamide solution (200 ml) of 7% hydrochloric acid was slowly added at 25 °C (±5 °C). The reaction mixture was continued to be stirred at 70°C (±5°C) for 4 to 6 hours. Afterwards, the reaction solution was cooled to 15 °C (±2 °C) and stirred for 8 to 10 hours to promote crystallization. The solid product was collected by filtration and washed with pre-cooled dichloromethane. Finally, the product was dried under vacuum at 30 to 40 °C to afford 4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride (120 g, 99% yield).

References

[1] Patent: WO2012/1486, 2012, A1. Location in patent: Page/Page column 18
[2] Journal of Organic Chemistry, 2015, vol. 80, # 14, p. 7019 - 7032
[3] Patent: EP1772455, 2007, A2. Location in patent: Page/Page column 9
[4] Journal of Organometallic Chemistry, 2009, vol. 694, # 13, p. 2092 - 2095
[5] Patent: US2004/24011, 2004, A1. Location in patent: Page 7

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride Preparation Products And Raw materials

Raw materials

2-Thiophenecarboxaldehyde Nitromethane Thiophene-2-ethylamine Formaldehyde 1,3-Dioxolane

Tetrahydrofuran Ammonium chloride Ethyl acetate Lithium Aluminum Hydride Hydrochloric acid

Methanol Isopropyl alcohol Sulfuric acid

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Preparation Products

5,6,7,7a-Tetrahydro-5-(triphenylmethyl)thieno[3,2-c]pyridinone

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride Suppliers

Global( 400)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +8618949832763	info@tnjchem.com	China	2988	55
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	340	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	923	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2950	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Hefei TNJ Chemical Industry Co.,Ltd.	55
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58
NINGBO INNO PHARMCHEM CO., LTD.	58
Shenzhen Nexconn Pharmatechs Ltd	58
Jinan Finer Chemical Co., Ltd	58

View Lastest Price from 4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-25	4,5,6,7-Tetrahydrothieno[3,2-c]pyridine (hydrochloride) 28783-41-7	$6.00	1KG	99%		Henan Fengda Chemical Co., Ltd
2025-04-04	4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride 28783-41-7		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-11-06	4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride 28783-41-7	$10.00	1Kg/Bag	99%	20 Tons	Hebei Zhanyao Biotechnology Co. Ltd

4,5,6,7-Tetrahydrothieno[3,2-c]pyridine (hydrochloride)
28783-41-7
$6.00
99%
Henan Fengda Chemical Co., Ltd

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride
28783-41-7
98%
Henan Aochuang Chemical Co.,Ltd.

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride
28783-41-7
$10.00
99%
Hebei Zhanyao Biotechnology Co. Ltd

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride Spectrum

4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride(28783-41-7)¹HNMR

28783-41-7(4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride)Related Search:

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Choline chloride L-Lysine hydrochloride Polyvinyl chloride

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4,5,6.7-Tetrahydro-thienol[3,2-c]pyridine HCl Thieno[3,2-c]pyridine, 4,5,6,7-tetrahydro-, hydrochloride Clopidogrel Thieno IMpurity 4,5,6,7-Tetrahydrothieno[3,2-c]pyridine hydrochloride, 96%, 96% TTP 4,5,6,7-Tetrahydrothieno 3,2-c Pyridine 4,5,6,7-tetrahydrothineo [3,2-c]pyridine hydrochloride 4,5,6,7-tetrahydrotieno[3,2-c]pyridinium chloride 4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE HCl(TTP) 4,5,6,7-tetrahydrothieno[3,2-c]pyridinium chloride Tetrahydrothieno pyridine HCl 4,5,6,7-Tetrahydrothieon[3,2-C]pyridine,HCl 4,5,6,7-Tetrahydrothieon[3,2-C]pyridine,hydrochloride Thieno[3,2-c]pyridine, 4,5,6,7-tetrahydro-, hydrochloride (1:1) 4,5,6,7-tetrahydrothieno[3,2-c]pyridine(SALTDATA: HCl) 4,5,6,7-Tetrahydrothiophene[3,2-c]pyridine hydrochloride 4,5,6,7-Tetrahydrothieno[3,2-c]pyridine hydrochloride ,98% 6,7-Dihydro-4H-thieno[3,2-c]pyridine Hydrochloride 4,5,6,7-TET RAH YDROTHIENO[3,2-C]PYRIDE Zidovudine impurity F 2-c]pyridine HCl 7-Tetrahydrothieno[3 Clopidogrel Thienopyridine Impurity Clopidogrel Impurity 24 HCl Clopidogrel-7 TTP 4,5,6,7-Tetrahydrothieno[3,2-c]Pyridine HCL Clopidogrel Thieno Impurity HCl Pragrace Impurity 23 Clopidogrel Impurity 56 4,5,6,7-Tetrahydrothieno[3,2-c]pyridine hydrochloride (Clopidogrel Impurity) Clopidogrel Impurities195 Clopidogrel Impurities6 4,5,6,7-Tetrahydrothieno[3,2,-c] pyridine hydrochlorideQ: What is 4,5,6,7-Tetrahydrothieno[3,2,-c] pyridine hydrochloride Q: What is the CAS Number of 4,5,6,7-Tetrahydrothieno[3,2,-c] pyridine hydrochloride Q: What is the storage condition of 4,5,6,7-Tetrahydrothieno[3,2,-c] pyridine hydrochloride Q: What are the applications of 4,5,6,7-Tetrahydrothieno[3,2,-c] pyridine hydrochloride Al 4,5,6,7 -Teirahydro [3,2-C] Thieno Pyridine Hydrochloride Tetrahydrothieno pyridine (THTP) 4,5,6,7-Tetrahydrothiopheno[3,2-c] Pyridine HCl (from Route-I) Clopidogrel EP Impurity 22 Prasugrel Impurity 23 HCl 4,5,6,7-TETRAHYDROTHIENO[3,2,C] PYRIDINE HCL 4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE HYDROCHLORIDE Tetrahydrothienopyridine Hydrochloride 28783-41-7 C7H9NSClH C7H9NSHClC7H10ClNS C7H9SNHCl C7H9NSHCl C7H10ClNS Prasugrel Intermediates Heterocycle-Pyridine series Heterocyclic Compounds Bases & Related Reagents Heterocycles Nucleotides Sulfur & Selenium Compounds Intermediates