3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID
- CAS No.
- 67-30-1
- Chemical Name:
- 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID
- Synonyms
- TETRAC;Tetrac, 10 mM in DMSO;tetraiodothyroaceticacid;Liothyronine EP Impurity D;Levothyroxine – Impurity D;Levothyroxine EP Impurity D;Linagliptin Impurity CD10097;Liothyronine Sodium Impurity D;3,5,3’,5’-tetraiodothyroacetique;Liothyronine Sodium EP Impurity D
- CBNumber:
- CB6124010
- Molecular Formula:
- C14H8I4O4
- Molecular Weight:
- 747.83
- MDL Number:
- MFCD00055932
- MOL File:
- 67-30-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3,3′,5,5′-Tetraiodothyroacetic acid | T3787 | 25mg | $134.9 |
| 3,3′,5,5′-Tetraiodothyroacetic acid | T3787 | 100mg | $420 |
| 3,3',5,5'-Tetraiodothyroacetic Acid | T3730 | 100MG | $229 |
| 3,3',5,5'-Tetraiodothyroacetic Acid | T3730 | 500MG | $695 |
| 3,5,3'',5''-TetraiodoThyroaceticAcid | T296125 | 50mg | $100 |
| More product size | |||
| Melting point | 219-220 °C (decomp) |
|---|---|
| Boiling point | 544.8±50.0 °C(Predicted) |
| Density | 2.727±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | acetone: soluble19.60 - 20.40mg/mL, clear, colorless (or faintly yellow to yellow) |
| pka | 3.98±0.10(Predicted) |
| form | powder to crystal |
| color | White to Yellow to Green |
| InChI | InChI=1S/C14H8I4O4/c15-8-4-7(5-9(16)13(8)21)22-14-10(17)1-6(2-11(14)18)3-12(19)20/h1-2,4-5,21H,3H2,(H,19,20) |
| InChIKey | PPJYSSNKSXAVDB-UHFFFAOYSA-N |
| SMILES | C1(CC(O)=O)=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1 |
| FDA UNII | PA7UX1FFYQ |
| UNSPSC Code | 12352106 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300 | |||||||||
| Precautionary statements | P264-P301+P310 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T+ | |||||||||
| Risk Statements | 28 | |||||||||
| Safety Statements | 45 | |||||||||
| RIDADR | UN 2811 6.1/PG 1 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CY1585800 | |||||||||
| HS Code | 2916.39.7900 | |||||||||
| HazardClass | 6.1 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Acute Tox. 2 Oral | |||||||||
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (300g or 300ml) | |||||||||
| NFPA 704 |
|
3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T3787 | 3,3′,5,5′-Tetraiodothyroacetic acid | 67-30-1 | 25mg | $134.9 | 2025-07-31 | Buy |
| Sigma-Aldrich | T3787 | 3,3′,5,5′-Tetraiodothyroacetic acid | 67-30-1 | 100mg | $420 | 2025-07-31 | Buy |
| TCI Chemical | T3730 | 3,3',5,5'-Tetraiodothyroacetic Acid | 67-30-1 | 100MG | $229 | 2025-07-31 | Buy |
| TCI Chemical | T3730 | 3,3',5,5'-Tetraiodothyroacetic Acid | 67-30-1 | 500MG | $695 | 2025-07-31 | Buy |
| TRC | T296125 | 3,5,3'',5''-TetraiodoThyroaceticAcid | 67-30-1 | 50mg | $100 | 2021-12-16 | Buy |
3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Chemical Properties,Uses,Production
Uses
Thyroid hormone analogue
Uses
3,3′,5,5′-Tetraiodothyroacetic acid has been used:
- as a positive control to study the effects of ioxynil (IOX)
- diethylstilbestrol (DES) exposure on zebrafish embryos
- to study its effects on long-term potentiation (LTP) and long-term depression (LTD) in the dentate gyrus in urethane-anesthetized male rats
- to determine its influence on the actions of thyroid-stimulating hormone
- thyroid-stimulating immunoglobulins in orbital fibroblast
Definition
ChEBI: A monocarboxylic acid that is thyroacetic acid carrying four iodo substituents at positions 3, 3', 5 and 5'.
Biochem/physiol Actions
Studies in rats have reported that Tetrac may regulate TSH secretion under in vivo conditions1.
in vivo
Tetrac (35 μg; p.o. for 40 days) inhibits tumor inoculation, growth and integrin expression in mice[4].
| Animal Model: | Wild-type male Balb/C mice aged 8 weeks are inoculated with 102B16F10 or B16LS9 cells[4] |
| Dosage: | 35 μg per day |
| Administration: | P.o. (added to the drinking water) daily for 40 days |
| Result: | Delayed the onset of ocular melanoma. Reduced the S-100 and integrin staining level in the B16F10 mice model. |
3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Moxin Chemicals | +86-17320513646 +8617320513646 | anna@molcoo.com | China | 10000 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3982 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2251 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9629 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
View Lastest Price from 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-01-20 | Tetrac
67-30-1
|
US $39.00-118.00 / mg | 99.04% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2025-12-16 | Levothyroxine EP Impurity D
67-30-1
|
US $0.00-0.00 / mg | 30mg | 95 | 100000 | Moxin Chemicals | |
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2020-01-10 | 2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid
67-30-1
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-

- Tetrac
67-30-1
- US $39.00-118.00 / mg
- 99.04%
- TargetMol Chemicals Inc.
-

- Levothyroxine EP Impurity D
67-30-1
- US $0.00-0.00 / mg
- 95
- Moxin Chemicals
-
![2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/ba922577-bf1b-4b22-8c08-439a461c857d.jpg)
- 2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid
67-30-1
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
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