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Adrenorphin, Free Acid

CAS No.
88866-92-6
Chemical Name:
Adrenorphin, Free Acid
Synonyms
Metorphacid;ADRENORPHIN;METORPHAMIDE;METORPHINAMIDE;ADRENORPHIN (FREE ACID);METORPHAMIDE (FREE ACID);Adrenorphin, ≥95% (HPLC);Tyr-Gly-Gly-Phe-Arg-Arg-Val;8-L-Valineadrenorphin (human);TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL
CBNumber:
CB6129590
Molecular Formula:
C44H68N14O10S
Molecular Weight:
985.16
MDL Number:
MFCD00076434
MOL File:
88866-92-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:30

Adrenorphin, Free Acid Properties

Density 1.42±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility ≥27.75 mg/mL in H2O with ultrasonic; ≥5.64 mg/mL in EtOH with ultrasonic; ≥98.5 mg/mL in DMSO
form solid
pka 3.34±0.10(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany  3

Adrenorphin, Free Acid price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T8156 Adrenorphin ≥95% (HPLC) 88866-92-6 1mg $163 2022-05-15 Buy
Biosynth FM109982 Metorphamide (free acid) 88866-92-6 5mg $900 2026-06-04 Buy
Biosynth FM109982 Metorphamide (free acid) 88866-92-6 2mg $900 2026-06-04 Buy
Biosynth FM109982 Metorphamide (free acid) 88866-92-6 1mg $900 2026-06-04 Buy
Biosynth FM109982 Metorphamide (free acid) 88866-92-6 10mg $1117.3 2026-06-04 Buy
Product number Packaging Price Buy
T8156 1mg $163 Buy
FM109982 5mg $900 Buy
FM109982 2mg $900 Buy
FM109982 1mg $900 Buy
FM109982 10mg $1117.3 Buy

Adrenorphin, Free Acid Chemical Properties, Uses, Production

Uses

Metorphacid Trifluoroacetate Salt is amino acid sequence; protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components.

Biological Activity

adrenorphin, also sometimes referred to as metorphamide, is an endogenous, c-terminally amidated, opioid octapeptide that is produced from proteolytic cleavage of proenkephalin a and is widely distributed throughout the mammalian brain(1). it was named based on the fact that it was originally detected in human phaeochromocytoma tumour derived from the adrenal medulla, and was subsequently found in normal human and bovine adrenal medulla as well. adrenorphin exhibits potent opioid activity, acting as a balanced μ- and κ-opioid receptor agonist while having no effects on δ-opioid receptors(2). it possesses analgesic and respiratory deppresive properties(3).figure 1 proteolytic cleavage of proenkephalin a

References

1. Matsuo H, Miyata A, Mizuno K (1983). "Novel C-terminally amidated opioid peptide in human phaeochromocytoma tumour". Nature 305 (5936): 721–3.2. Weber E, Esch FS, Böhlen P et al. (December 1983). "Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain". Proceedings of the National Academy of Sciences of the United States of America 80 (23): 7362–6.3. Xu SF, Lu WX, Zhou KR et al. (April 1985). "The analgesic and respiratory depressant actions of metorphamide in mice and rabbits". Neuropeptides 6 (2): 121–31.

Adrenorphin, Free Acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 85)
Supplier Tel Email Country ProdList Advantage
Alabiochem Tech.Co., Ltd. 512-58900862 400-0707518 sales@alabiochem.com China 988 59
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55
ApexBio Technology LLC +1-832-696-8203 info@apexbt.com United States 477 60
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Watson Biotechnology Co.,Ltd 027-59207879 1972026995 18140587686 sales@3600chem.com China 4143 55
Shanghai Xilong Biochemical Technology Co., Ltd. 021-52907766-8042 China 9928 58

View Latest Price from Adrenorphin, Free Acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	ADRENORPHIN pictures 2020-02-19 ADRENORPHIN
88866-92-6
$7.00 1KG 99% 100kg Career Henan Chemical Co
	ADRENORPHIN pictures 2020-02-19 ADRENORPHIN
88866-92-6
$7.00 1KG 99% 100kg Career Henan Chemical Co

Adrenorphin, Free Acid Spectrum

METORPHAMIDE (FREE ACID) METORPHINAMIDE METORPHAMIDE H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-OH ADRENORPHIN (FREE ACID) ADRENORPHIN TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL Adrenorphin, ≥95% (HPLC) 8-L-Valineadrenorphin (human) Metorphacid Tyr-Gly-Gly-Phe-Arg-Arg-Val Metorphamide (free acid) H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-OH L-Valine, L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl- 88866-92-6 C44H68N14O10S Biochemicals and Reagents Amino Acids and Peptides BioChemical Peptides Other Peptides Neuroscience