9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL
- CAS No.
- 124027-47-0
- Chemical Name:
- 9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL
- Synonyms
- PD-131620;1-Hydroxytacrine;9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL
- CBNumber:
- CB6131870
- Molecular Formula:
- C13H14N2O
- Molecular Weight:
- 214.26
- MDL Number:
- MFCD00600017
- MOL File:
- 124027-47-0.mol
| Melting point | 245℃ |
|---|---|
| Boiling point | 450.3±45.0 °C(Predicted) |
| Density | 1.315±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 13.47±0.20(Predicted) |
| FDA UNII | Y2P6NV151K |
9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0010391 | 1-HYDROXYTACRINE 95.00% | 124027-47-0 | 1G | $1439.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010391 | 1-HYDROXYTACRINE 95.00% | 124027-47-0 | 5G | $2477.48 | 2021-12-16 | Buy |
| Crysdot | CD11318925 | Velnacrine 95+% | 124027-47-0 | 25mg | $110 | 2021-12-16 | Buy |
| Ambeed | A134094 | Velnacrine 95% | 124027-47-0 | 50mg | $136 | 2021-12-16 | Buy |
| Ambeed | A134094 | Velnacrine 95% | 124027-47-0 | 100mg | $176 | 2021-12-16 | Buy |
9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL Chemical Properties,Uses,Production
Uses
Velnacrine (HP 029 free base) is an inhibitor for acetylcholinesterase (AChE), with an IC50 of 3.27 μM. Velnacrine reverses the Scopolamine (HY-N0296)-induced amnesia in rat models, and exhibits acute toxicity with LD50 of 65 mg/kg[1].
Definition
ChEBI: 9-amino-1,2,3,4-tetrahydroacridin-1-ol is a member of acridines.
IC 50
AChE: 3.27 μM (IC50)
References
[1] Tabarrini O, et al., Velnacrine thiaanalogues as potential agents for treating Alzheimer's disease. Bioorg Med Chem. 2001 Nov;9(11):2921-8. DOI:10.1016/s0968-0896(01)00171-7
9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38838 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Chembest Research Laboratories Limited | +86-21-20908456 | sales@BioChemBest.com | China | 6005 | 61 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10266 | 58 |
| Acesys Pharmatech | 18860950986 | tangmanman@zenjipharma.com | China | 1733 | 55 |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189 | mychess007@163.com | China | 1994 | 55 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9923 | 65 |
| Suzhou Ryway Biotech Co., Ltd | +86-18013160973 | info@rywaybio.com | China | 299 | 55 |
