4-Chloro-N-methylpicolinamide
- CAS No.
- 220000-87-3
- Chemical Name:
- 4-Chloro-N-methylpicolinamide
- Synonyms
- 4-Chloro-N-methylpicolinamide;4-CHLORO-N-METHYL-2-PYRIDINECARBOXAMIDE;4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE;oro-N-methyL;Sorafenib INT3;CAS:220000-87-3;4-Chloropyridine-2;IFLAB-BB F2108-0189;Sorafenib Impurity 06;-2-pyridinecarboxamide
- CBNumber:
- CB6134053
- Molecular Formula:
- C7H7ClN2O
- Molecular Weight:
- 170.6
- MDL Number:
- MFCD02185921
- MOL File:
- 220000-87-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T) | C2793 | 1g | $27 |
| 4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T) | C2793 | 5g | $106 |
| 4-Chloro-N-methylpyridine-2-carboxamide (>90%) | TRC-C379950-250MG | 250mg | $84 |
| 4-CHLORO-N-METHYLPICOLINAMIDE 97% | CL0248 | 5G | $23 |
| 4-CHLORO-N-METHYLPICOLINAMIDE 97% | CL0248 | 25G | $29 |
| More product size | |||
| Melting point | 41-43°C |
|---|---|
| Boiling point | 317.8±27.0 °C(Predicted) |
| Density | 1.264±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met |
| form | Solid |
| pka | 13.41±0.46(Predicted) |
| color | Off-White to Light Yellow |
| InChI | InChI=1S/C7H7ClN2O/c1-9-7(11)6-4-5(8)2-3-10-6/h2-4H,1H3,(H,9,11) |
| InChIKey | BGVBBMZMEKXUTR-UHFFFAOYSA-N |
| SMILES | C1(C(NC)=O)=NC=CC(Cl)=C1 |
| CAS DataBase Reference | 220000-87-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36 | |||||||||
| Safety Statements | 26 | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
4-Chloro-N-methylpicolinamide price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2793 | 4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T) | 220000-87-3 | 1g | $27 | 2026-04-30 | Buy |
| TCI Chemical | C2793 | 4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T) | 220000-87-3 | 5g | $106 | 2026-04-30 | Buy |
| TRC | TRC-C379950-250MG | 4-Chloro-N-methylpyridine-2-carboxamide (>90%) | 220000-87-3 | 250mg | $84 | 2026-06-03 | Buy |
| AstaTech | CL0248 | 4-CHLORO-N-METHYLPICOLINAMIDE 97% | 220000-87-3 | 5G | $23 | 2026-04-30 | Buy |
| AstaTech | CL0248 | 4-CHLORO-N-METHYLPICOLINAMIDE 97% | 220000-87-3 | 25G | $29 | 2026-04-30 | Buy |
4-Chloro-N-methylpicolinamide Chemical Properties,Uses,Production
Description
4-Chloro-N-methylpicolinamide is a polar organic compound that interacts with hydrogen bonds. It has been shown to inhibit the value-added of cancer cells by inhibiting protein synthesis to inhibit the growth of human hepatocellular carcinoma cells, bcr/abl kinase, and hct116 cells, and is a candidate for cancer treatment. Studies have shown that it also inhibits the proliferation of MDA-MB231 breast cancer cells by blocking growth factor activity. In addition, 4-Chloro-N-methylpicolinamide is a pharmaceutical intermediate component used in the preparation of the antineoplastic drugs regorafenib and sorafenib.
Chemical Properties
Pale-Yellow Solid
Uses
4-Chloro-N-methylpyridine-2-carboxamide (>90%) (cas# 220000-87-3) is a compound useful in organic synthesis.
4-Chloro-N-methylpicolinamide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yangzhou Qinyuan Pharmatech Co.,ltd | +86-18752526868 +86-18752526868 | jennysun@yzqyyykj.com | China | 80 | 58 |
| Shandong Jihui Chemical Co., Ltd. | +86-15053042019 | sales@jihuichem.com | China | 34 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21533 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2993 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2945 | 58 |
| Lotusland Life Sciences | +8615821988213 | info@longyupharma.com | China | 2411 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 |
View Lastest Price from 4-Chloro-N-methylpicolinamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-09-07 | N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
|
$12.00 | 1KG | 99% | 100mt | Jinan Finer Chemical Co., Ltd | |
![]() |
2026-09-07 | N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
|
10g | 99%min | 10000g | WUHAN FORTUNA CHEMICAL CO., LTD | ||
![]() |
2026-08-20 | N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-

- N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
- $12.00
- 99%
- Jinan Finer Chemical Co., Ltd
-

- N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
- $1.10
- 99.00%
- Dideu Industries Group Limited








