4-Chloro-N-methylpicolinamide
- CAS No.
- 220000-87-3
- Chemical Name:
- 4-Chloro-N-methylpicolinamide
- Synonyms
- 4-Chloro-N-methylpicolinamide;4-CHLORO-N-METHYL-2-PYRIDINECARBOXAMIDE;4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE;oro-N-methyL;Sorafenib INT3;CAS:220000-87-3;4-Chloropyridine-2;IFLAB-BB F2108-0189;Sorafenib Impurity 06;-2-pyridinecarboxamide
- CBNumber:
- CB6134053
- Molecular Formula:
- C7H7ClN2O
- Molecular Weight:
- 170.6
- MDL Number:
- MFCD02185921
- MOL File:
- 220000-87-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T) | C2793 | 1g | $33 |
| 4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T) | C2793 | 5g | $132 |
| 4-Chloro-N-methylpyridine-2-carboxamide(>90%) | C379950 | 25g | $440 |
| 4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE 95.00% | HCH0013173 | 1G | $671.75 |
| 4-Chloro-N-methyl-2-pyridinecarboxamide 99.52% | CS-M2758 | 500g | $353 |
| More product size | |||
| Melting point | 41-43°C |
|---|---|
| Boiling point | 317.8±27.0 °C(Predicted) |
| Density | 1.264±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met |
| form | Solid |
| pka | 13.41±0.46(Predicted) |
| color | Off-White to Light Yellow |
| InChI | InChI=1S/C7H7ClN2O/c1-9-7(11)6-4-5(8)2-3-10-6/h2-4H,1H3,(H,9,11) |
| InChIKey | BGVBBMZMEKXUTR-UHFFFAOYSA-N |
| SMILES | C1(C(NC)=O)=NC=CC(Cl)=C1 |
| CAS DataBase Reference | 220000-87-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36 | |||||||||
| Safety Statements | 26 | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
4-Chloro-N-methylpicolinamide price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2793 | 4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T) | 220000-87-3 | 1g | $33 | 2025-07-31 | Buy |
| TCI Chemical | C2793 | 4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T) | 220000-87-3 | 5g | $132 | 2025-07-31 | Buy |
| TRC | C379950 | 4-Chloro-N-methylpyridine-2-carboxamide(>90%) | 220000-87-3 | 25g | $440 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0013173 | 4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE 95.00% | 220000-87-3 | 1G | $671.75 | 2021-12-16 | Buy |
| ChemScene | CS-M2758 | 4-Chloro-N-methyl-2-pyridinecarboxamide 99.52% | 220000-87-3 | 500g | $353 | 2021-12-16 | Buy |
4-Chloro-N-methylpicolinamide Chemical Properties,Uses,Production
Description
4-Chloro-N-methylpicolinamide is a polar organic compound that interacts with hydrogen bonds. It has been shown to inhibit the value-added of cancer cells by inhibiting protein synthesis to inhibit the growth of human hepatocellular carcinoma cells, bcr/abl kinase, and hct116 cells, and is a candidate for cancer treatment. Studies have shown that it also inhibits the proliferation of MDA-MB231 breast cancer cells by blocking growth factor activity. In addition, 4-Chloro-N-methylpicolinamide is a pharmaceutical intermediate component used in the preparation of the antineoplastic drugs regorafenib and sorafenib.
Chemical Properties
Pale-Yellow Solid
Uses
4-Chloro-N-methylpyridine-2-carboxamide (>90%) (cas# 220000-87-3) is a compound useful in organic synthesis.
4-Chloro-N-methylpicolinamide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yangzhou Qinyuan Pharmatech Co.,ltd | +86-18752526868 +86-18752526868 | jennysun@yzqyyykj.com | China | 83 | 58 |
| Shandong Jihui Chemical Co., Ltd. | +8615053042019 | sales@jihuichem.com | China | 34 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21595 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
View Lastest Price from 4-Chloro-N-methylpicolinamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-04 | N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
|
US $12.00 / KG | 1KG | 99% | 100mt | Jinan Finer Chemical Co., Ltd | |
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2026-03-04 | N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
|
US $0.00-0.00 / g | 10g | 99%min | 10000g | WUHAN FORTUNA CHEMICAL CO., LTD | |
![]() |
2026-02-28 | N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
|
US $0.00-0.00 / kg | 1kg | Purity: 98% | 50tons | Shandong Jihui Chemical Co., Ltd. |
-

- N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
- US $12.00 / KG
- 99%
- Jinan Finer Chemical Co., Ltd
-

- N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
- US $0.00-0.00 / g
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
- US $0.00-0.00 / kg
- Purity: 98%
- Shandong Jihui Chemical Co., Ltd.
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