1-(1,2R-dihexadecanoylphosphatidyl)inositol-4,5-diphosphate, tetraammonium salt
- CAS No.
- Chemical Name:
- 1-(1,2R-dihexadecanoylphosphatidyl)inositol-4,5-diphosphate, tetraammonium salt
- Synonyms
- PTDINS-(4,5)-P2 (1,2-DIPALMITOYL) AMMONIUM SALT;PHOSPHATIDYLINOSITOL-4,5-DIPHOSPHATE C-16 AMMONIUM SALT;1-(1,2R-dihexadecanoylphosphatidyl)inositol-4,5-diphosphate, tetraammonium salt
- CBNumber:
- CB6135232
- Molecular Formula:
- C41H93N4O19P3
- Molecular Weight:
- 1039.11
- MDL Number:
- MFCD05863730
- MOL File:
- Mol file
1-(1,2R-dihexadecanoylphosphatidyl)inositol-4,5-diphosphate, tetraammonium salt price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 64924 | PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (ammonium salt) ≥98% | 100μg | $70 | 2026-04-30 | Buy | |
| Cayman Chemical | 64924 | PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (ammonium salt) ≥98% | 500μg | $303 | 2026-04-30 | Buy | |
| Cayman Chemical | 64924 | PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (ammonium salt) ≥98% | 1mg | $535 | 2026-04-30 | Buy |
1-(1,2R-dihexadecanoylphosphatidyl)inositol-4,5-diphosphate, tetraammonium salt Chemical Properties,Uses,Production
Description
PtdIns-(4,5)-P2 incorporated into membrane lipids can bind to important proteins such as Group IV cPLA2 and PLCδ1, enhancing their adherence to the membrane and increasing the rate of substrate hydrolysis.1 PtdIns-(4,5)-P2 can be further phosphorylated to give triphosphates such as PtdIns-(3,4,5)-P3. It can also be cleaved by PI-specific PLC to give inositol triphosphates. The diacyl glycerol and IP3 generated by this PLC-cleavage are also part of a complex biochemical and signal transduction cascade which has not been entirely elucidated. For some additional reading, please see references 2, 3, and 4.WARNING This product is not for human or veterinary use.
References
[1] M MOSIOR E A D D A Six. Group IV cytosolic phospholipase A2 binds with high affinity and specificity to phosphatidylinositol 4,5-bisphosphate resulting in dramatic increases in activity.[J]. The Journal of Biological Chemistry, 1998, 273 4: 2184-2191. DOI: 10.1074/jbc.273.4.2184
[2] MAJERUS P W. Inositol phosphate biochemistry.[J]. Annual review of biochemistry, 1992, 61: 225-250. DOI: 10.1146/annurev.bi.61.070192.001301
[3] L J PIKE L C. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains.[J]. The Journal of Biological Chemistry, 1996, 271 43: 26453-26456. DOI: 10.1074/jbc.271.43.26453
[4] BERRIDGE M J. Inositol trisphosphate and calcium signalling[J]. Nature, 1993, 361 6410: 315-325. DOI: 10.1038/361315a0
1-(1,2R-dihexadecanoylphosphatidyl)inositol-4,5-diphosphate, tetraammonium salt Preparation Products And Raw materials
Raw materials
Preparation Products
1-(1,2R-dihexadecanoylphosphatidyl)inositol-4,5-diphosphate, tetraammonium salt Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| ChemeGen | 18818260767 | 2625930290@qq.com | China | 6966 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 18019219489 18901678489 | tech@zzbioco.com | China | 12062 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
| ChemeGen | 58 |
| SHANGHAI ZZBIO CO., LTD. | 58 |
