M 8218
- CAS No.
- 87827-02-9
- Chemical Name:
- M 8218
- Synonyms
- Penehyclidine;M 8218;BENC-003;M 8218 / Penehyclidine;Benzenemethanol, α-[(1-azabicyclo[2.2.2]oct-3-yloxy)methyl]-α-cyclopentyl-;benzeneMethanol, a-[(1-azabicyclo[2.2.2]oct-3-yloxy)Methyl]-a-cyclopentyl- hydrochloride
- CBNumber:
- CB61374391
- Molecular Formula:
- C20H29NO2
- Molecular Weight:
- 315.45
- MDL Number:
- MFCD27977255
- MOL File:
- 87827-02-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Penequine 98% | 3000B | 1mg | $119 |
| Penequine 98% | 3000B | 5mg | $290 |
| Penequine 98% | 3000B | 10mg | $490 |
| Penequine 98% | 3000B | 25mg | $890 |
| Penequine 98% | 3000B | 100mg | $1890 |
| Boiling point | 461.0±35.0 °C(Predicted) |
|---|---|
| Density | 1.14±0.1 g/cm3(Predicted) |
| pka | 13+-.0.29(Predicted) |
| FDA UNII | 353CX8CSHD |
M 8218 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AvaChem | 3000B | Penequine 98% | 87827-02-9 | 1mg | $119 | 2026-05-22 | Buy |
| AvaChem | 3000B | Penequine 98% | 87827-02-9 | 5mg | $290 | 2026-05-22 | Buy |
| AvaChem | 3000B | Penequine 98% | 87827-02-9 | 10mg | $490 | 2026-05-22 | Buy |
| AvaChem | 3000B | Penequine 98% | 87827-02-9 | 25mg | $890 | 2026-05-22 | Buy |
| AvaChem | 3000B | Penequine 98% | 87827-02-9 | 100mg | $1890 | 2026-05-22 | Buy |
M 8218 Chemical Properties,Uses,Production
Uses
Penehyclidine, a anticholinergic agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation[1][2].
IC 50
mAChR1; mAChR3; NF-κB
References
[1] Zhi-Yuan Chen, et al. The Mechanism of Penehyclidine Hydrochloride and Its Effect on the Inflammatory Response of Lung Tissue in Rats with Chronic Obstructive Pulmonary Disease During Mechanical Ventilation. Int J Chron Obstruct Pulmon Dis. 2021 Mar 31;16:877-885. DOI:10.2147/COPD.S295329
[2] Xiao HT, et al. Penehyclidine hydrochloride: a potential drug for treating COPD by attenuating Toll-like receptors. Drug Des Devel Ther. 2012;6:317-22. DOI:10.2147/DDDT.S36555
M 8218 Preparation Products And Raw materials
Raw materials
Preparation Products
M 8218 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +86-15988602810 | sales@anbuchem.com | China | 3429 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9883 | 50 |
| Chengdu DingDang Pharmaceutical Co., Ltd. | 028-86040038 | market@dingdangchem.com | China | 1853 | 55 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28764 | 58 |
| Chengdu Novel Biomedical Co., Ltd. | 028-85255396 18302801538 | cdnovell@163.com | China | 2442 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| QUALITY CONTROL SOLUTIONS LTD. | +86-0755-66853366 +8613670046396 | export03@qcsrm.com | China | 24318 | 58 |
| Yulin Runtianchang Chemical Co., Ltd | 15890160877; 15890142075 | 3555133855@qq.com | China | 9972 | 58 |
View Lastest Price from M 8218 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-15 | Penehyclidine
87827-02-9
|
98% | 1000 KGS | Zhengzhou Anbu Chem Co.,Ltd |
-
- Penehyclidine
87827-02-9
- $0.00
- 98%
- Zhengzhou Anbu Chem Co.,Ltd
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