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4-Amino-6-chloropyrimidine-5-carbaldehyde

4-Amino-6-chloropyrimidine-5-carbaldehyde Structure
4-Amino-6-chloropyrimidine-5-carbaldehyde structure
CAS No.
14160-93-1
Chemical Name:
4-Amino-6-chloropyrimidine-5-carbaldehyde
Synonyms
RARECHEM AK ML 0569;4-aMino-6-chloropyriMidin-5-carbaldehyde;4-AMI-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE;4-AMINO-6-CHLORO-5-PYRIMIDINECARBALDEHYDE;4-Chloro-6-aminopyrimidine-5-carbaldehyde;4-aMino-6-chloro-pyriMidine-5-carbaledhyde;5-PyriMidinecarbaldehyde, 4-aMino-6-chloro;4-AMINO-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE;4-Amino-6-chloropyrimidine-5-carboxaldehyde;4-AMINO-6-CHLORO-5-PYRIMIDINECARBOXALDEHYDE
CBNumber:
CB6139821
Molecular Formula:
C5H4ClN3O
Molecular Weight:
157.56
MDL Number:
MFCD03789626
MOL File:
14160-93-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-11 15:09:41
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4-Amino-6-chloropyrimidine-5-carbaldehyde Properties

Melting point >300°C
Boiling point 355.9±42.0 °C(Predicted)
Density 1.548±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form Solid
pka 0.72±0.10(Predicted)
Appearance Off-white to light yellow Solid
Sensitive Air Sensitive
InChI InChI=1S/C5H4ClN3O/c6-4-3(1-10)5(7)9-2-8-4/h1-2H,(H2,7,8,9)
InChIKey GOJNFUXEBVBARW-UHFFFAOYSA-N
SMILES C1=NC(Cl)=C(C=O)C(N)=N1
EPA Substance Registry System 5-Pyrimidinecarboxaldehyde, 4-amino-6-chloro- (14160-93-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  43-36/37/38
Safety Statements  36/37-36/37/39-26
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29335990
NFPA 704
0
2 0

4-Amino-6-chloropyrimidine-5-carbaldehyde price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 295385 4-Amino-6-chloropyrimidine-5-carbaldehyde Asreported 14160-93-1 500mg $333 2026-06-03 Buy
Usbiological 295385 4-Amino-6-chloropyrimidine-5-carbaldehyde Asreported 14160-93-1 1g $483 2026-06-03 Buy
Usbiological 295385 4-Amino-6-chloropyrimidine-5-carbaldehyde Asreported 14160-93-1 2g $654 2026-06-03 Buy
Usbiological 295385 4-Amino-6-chloropyrimidine-5-carbaldehyde Asreported 14160-93-1 5g $1248 2026-06-03 Buy
Usbiological 295385 4-Amino-6-chloropyrimidine-5-carbaldehyde Asreported 14160-93-1 10g $1793 2026-06-03 Buy
Product number Packaging Price Buy
295385 500mg $333 Buy
295385 1g $483 Buy
295385 2g $654 Buy
295385 5g $1248 Buy
295385 10g $1793 Buy

4-Amino-6-chloropyrimidine-5-carbaldehyde Chemical Properties, Uses, Production

Chemical Properties

Yellow solid

Uses

4-Amino-6-chloropyrimidine-5-carbaldehyde is an important pharmaceutical intermediate compound that can be used in the preparation of ENPP1 inhibitors [1]. Furthermore, it serves as a key starting material for the synthesis of novel 4-amino-pyrimidine-5-formyl oxime VEGFR-2 inhibitors [2].

References

[1] Sun, Y., Chen, M., Han, Y. (2024). Discovery of Pyrido[2,3-d]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment. Journal of Medicinal Chemistry, 67 5, 3986–4006. https://doi.org/10.1021/acs.jmedchem.3c02288
[2] Huang, S., Li, R., LaMontagne, K. R., Greenberger, L. M., & Connolly, P. J. (2011). 4-Aminopyrimidine-5-carbaldehyde oximes as potent VEGFR-2 inhibitors. Part II. Bioorganic & Medicinal Chemistry Letters, 21 6, Pages 1815-1818. https://doi.org/10.1016/j.bmcl.2011.01.053

4-Amino-6-chloropyrimidine-5-carbaldehyde Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide Toluene 4,6-Dihydroxypyrimidine Phosphorus oxitrichloride

Preparation Products

4-Amino-6-chloropyrimidine-5-carbaldehyde Suppliers

Global Suppliers ( 163)
Supplier Tel Email Country ProdList Advantage
Nanjing Nohon Biological Technology Co., Ltd. 025-85767923 18512596075; sales@nuoxibio.com China 978 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7880 64
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
EnciPharmatech Co., Ltd 025-52714267-66 13813902930 stephen_shengll@hotmail.com China 231 64
Supplier Advantage
Nanjing Nohon Biological Technology Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
Wuhan Chemwish Technology Co., Ltd 56
Jia Xing Isenchem Co.,Ltd 66
Pure Chemistry Scientific Inc. 62
Tetranov Biopharm 64
Shanghai Longsheng chemical Co.,Ltd. 59
Chemsky（shanghai）International Co.,Ltd. 50
EnciPharmatech Co., Ltd 64

View Latest Price from 4-Amino-6-chloropyrimidine-5-carbaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-AMINO-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE pictures 2026-08-20 4-AMINO-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE
14160-93-1
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
4-AMINO-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE pictures 2019-07-06 4-AMINO-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE
14160-93-1
 $1.00 1kg as customer's need 1000kg Career Henan Chemical Co

4-Amino-6-chloropyrimidine-5-carbaldehyde Spectrum

4-AMINO-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE(14160-93-1)1HNMR

14160-93-1 (4-Amino-6-chloropyrimidine-5-carbaldehyde) Related Search:

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RARECHEM AK ML 0569 4-AMINO-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE 4-AMINO-6-CHLORO-5-PYRIMIDINECARBALDEHYDE 4-AMINO-6-CHLORO-5-PYRIMIDINECARBOXALDEHYDE 4-Amino-6-chloropyrimidine-5-carboxaldehyde 4-Amino-6-chloro-5-pyrimidinecarboxaldehyde ,96% 4-aMino-6-chloropyriMidin-5-carbaldehyde 5-PyriMidinecarbaldehyde, 4-aMino-6-chloro 4-Chloro-6-aminopyrimidine-5-carbaldehyde 5-PyriMidinecarboxaldehyde, 4-aMino-6-chloro- 4-aMino-6-chloro-pyriMidine-5-carbaledhyde 4-Amino-6-chloro-5-formylpyrimidine, 4-Amino-6-chloro-5-formyl-1,3-diazine 4-Amino-6-chloropyrimidine-5-carboxaldehyde,97% 4-AMINO-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE ISO 9001：2015 REACH 4-AMI-6-CHLORO-PYRIMIDINE-5-CARBALDEHYDE 14160-93-1 C5H4ClN3O Heterocycle-Pyrimidine series pyrimidine