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Ethyl trichloroacetate

CAS No.
515-84-4
Chemical Name:
Ethyl trichloroacetate
Synonyms
Ethyl 2,2,2-trichloroacetate;Acetic acid, trichloro-, ethyl ester;ethyl trichlo;Trichloroaceta;RARECHEM AL BI 1451;Ethyltrichloracetat;ethyltrichloracetate;Biapenem Impurity 45;Ethyl trichloroacetat;Tadalafil Impurity 69
CBNumber:
CB6143392
Molecular Formula:
C4H5Cl3O2
Molecular Weight:
191.44
MDL Number:
MFCD00000795
MOL File:
515-84-4.mol
MSDS File:
SDS
Last updated:2026-05-28 02:06:42
Product description Number Pack Size Price
Ethyl trichloroacetate 97% 163155 100g $118
Ethyl Trichloroacetate >97.0%(GC) T1504 25g $41
Ethyl Trichloroacetate >97.0%(GC) T1504 500g $224
Ethyl 2,2,2-Trichloroacetate TRC-E078315-5G 5g $91
Ethyl 2,2,2-Trichloroacetate TRC-E078315-2.5G 2.5g $74
More product size

Ethyl trichloroacetate Properties

Melting point 237 °C
Boiling point 168 °C (lit.)
Density 1.378 g/mL at 25 °C (lit.)
vapor pressure 2.34hPa at 25℃
refractive index n20/D 1.453(lit.)
Flash point 149 °F
storage temp. Store below +30°C.
solubility alcohol: miscible(lit.)
form clear liquid
color Colorless to Almost colorless
Water Solubility immiscible
Merck 14,9627
BRN 1761567
Dielectric constant 7.8(20℃)
InChI 1S/C4H5Cl3O2/c1-2-9-3(8)4(5,6)7/h2H2,1H3
InChIKey SJMLNDPIJZBEKY-UHFFFAOYSA-N
SMILES CCOC(=O)C(Cl)(Cl)Cl
LogP 2.22 at 25℃
CAS DataBase Reference 515-84-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII BR8FKN5Z55
NIST Chemistry Reference Acetic acid, trichloro-, ethyl ester(515-84-4)
EPA Substance Registry System Acetic acid, trichloro-, ethyl ester (515-84-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315
Precautionary statements  P264-P270-P280-P301+P312-P302+P352-P332+P313
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-37/39-24/25
RIDADR  2810
WGK Germany  1
TSCA  TSCA listed
HS Code  29154000
Storage Class 10 - Combustible liquids
Hazard Classifications Acute Tox. 4 Oral
Skin Irrit. 2
REACH Registrations Active
NFPA 704
2
2 0

Ethyl trichloroacetate price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 163155 Ethyl trichloroacetate 97% 515-84-4 100g $118 2026-04-30 Buy
TCI Chemical T1504 Ethyl Trichloroacetate >97.0%(GC) 515-84-4 25g $41 2026-04-30 Buy
TCI Chemical T1504 Ethyl Trichloroacetate >97.0%(GC) 515-84-4 500g $224 2026-04-30 Buy
TRC TRC-E078315-5G Ethyl 2,2,2-Trichloroacetate 515-84-4 5g $91 2026-06-03 Buy
TRC TRC-E078315-2.5G Ethyl 2,2,2-Trichloroacetate 515-84-4 2.5g $74 2026-06-03 Buy
Product number Packaging Price Buy
163155 100g $118 Buy
T1504 25g $41 Buy
T1504 500g $224 Buy
TRC-E078315-5G 5g $91 Buy
TRC-E078315-2.5G 2.5g $74 Buy

Ethyl trichloroacetate Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid with a menthol-like odor. It is miscible with ethanol, ether and benzene, but insoluble in water.

Uses

Ethyl trichloroacetate was used in the synthesis of dichlorocarbon precursor, phenyl(trichloromethyl)methyl.

Preparation

Ethyl trichloroacetate is synthesized from trichloroacetic acid and ethyl alcohol by the esterification reaction.
synthesis steps: Trichloroacetic acid(TCA), anhydrous ethyl alcohol and sulfuric acid are heated together and refluxed for 6 h. After cooling, the ester layer is separated by pouring into water, neutralized with 5-10% sodium carbonate solution, washed with water and dried overnight with anhydrous calcium chloride. After filtration, distillation was carried out to obtain the finished product. Yield 75%.

Application

Ethyl trichloroacetate can be used as solvent, organic synthesis, perfume and pharmaceutical intermediates.

Synthesis Reference(s)

The Journal of Organic Chemistry, 46, p. 3519, 1981 DOI: 10.1021/jo00330a028

General Description

Ethyl trichloroacetate undergoes atom-transfer radical addition reaction with styrene catalyzed by the Ru-pentamethylcyclopentadienyl complexes.

Purification Methods

Shake the ester with saturated aqueous Na2CO3 (three times), aqueous 50% CaCl2 (three times), saturated aqueous NaCl (twice), then distil over CaCl2 and redistil it under reduced pressure. [Beilstein 2 IV 514.]

Global( 291)Suppliers
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Hebei Chuanghai Biotechnology Co,.LTD
+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5228 58
Hebei Chuanghai Biotechnology Co., Ltd
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Henan Fengda Chemical Co., Ltd
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Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58

View Lastest Price from Ethyl trichloroacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl Trichloroacetate pictures 2026-05-28 Ethyl Trichloroacetate
515-84-4
$2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
Ethyl trichloroacetate pictures 2025-09-25 Ethyl trichloroacetate
515-84-4
$30.00 1KG 99% Henan Fengda Chemical Co., Ltd
Ethyl trichloroacetate pictures 2025-08-20 Ethyl trichloroacetate
515-84-4
1kg 99.99% 20 tons Chongqing Soarwin Technology Co., Ltd
ETHYL TRICHLOROACETATE TRICHLOROACETATE ETHYL ESTER TRICHLOROACETIC ACID ETHYL ESTER Acetic acid, 2,2,2-trichloroethyl ester Acetic acid, ester with trichloroethanol ethanoicacid,trichloro-,ethylester ethyltrichloracetate Ethyl trichloroacetate, 97.5% Trichloroaceta 2,2,2-trichloroacetic acid ethyl ester trichloro-aceticaciethylester Trichloroethyl acetate ETHYL TRICHLOROACETATE 98% (GC) ETHYL TRICHLOROACETATE PESTANAL, 250 MG Ethyl trichloroacetate, stabilized, 97% RARECHEM AL BI 1451 Acetic acid, trichloro-, ethyl ester Ethyl trichloroacetate, 97%, stab. with epoxy resin Ethyltrichloracetat ETHYL TRICHLOROACETATE , STABILIZED WITH EPOXY RESIN ETHYL TRICHLOROACETATE, STABILSED WITH EPOXY RESIN Ethyl trichloroacetate, 97%, stabilized Ethyl trichloroacetat Tadalafil Impurity 69 Ethyl Trichloroacetate, ≥ 97.0% Biapenem Impurity 45 Ethyl trichloroacetate, 96% ethyl trichlo Ethyl 2,2,2-trichloroacetate 515-84-4 C4H5Cl3O2 CCl3CO2CH2CH3 C4H5O2Cl3 C4H5C13O2 Cl3CCO2CH2CH3 Cl3CCOOC2H5 Building Blocks Carbonyl Compounds C2 to C5 Esters Organic Building Blocks C2 to C5 Carbonyl Compounds Esters Pharmaceutical Intermediates