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JACOLINE

CAS No.
480-76-2
Chemical Name:
JACOLINE
Synonyms
Jacolin;JACOLINE;(20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
CBNumber:
CB61438381
Molecular Formula:
C18H27NO7
Molecular Weight:
369.41
MDL Number:
MFCD00871325
MOL File:
480-76-2.mol
Last updated:2023-07-12 17:04:18
Product description Number Pack Size Price
Jacoline XJ161762 1mg $285.56
Jacoline XJ161762 2mg $393.54
Jacoline XJ161762 5mg $819.8
Jacoline XJ161762 10mg $1366.4
Jacoline XJ161762 20mg $2277.4

JACOLINE Properties

Melting point 221°C
Boiling point 583.5±50.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
pka 12.40±0.60(Predicted)
FDA UNII USC51AR5V5

JACOLINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth XJ161762 Jacoline 480-76-2 1mg $285.56 2026-06-05 Buy
Biosynth XJ161762 Jacoline 480-76-2 2mg $393.54 2026-06-05 Buy
Biosynth XJ161762 Jacoline 480-76-2 5mg $819.8 2026-06-05 Buy
Biosynth XJ161762 Jacoline 480-76-2 10mg $1366.4 2026-06-05 Buy
Biosynth XJ161762 Jacoline 480-76-2 20mg $2277.4 2026-06-05 Buy
Product number Packaging Price Buy
XJ161762 1mg $285.56 Buy
XJ161762 2mg $393.54 Buy
XJ161762 5mg $819.8 Buy
XJ161762 10mg $1366.4 Buy
XJ161762 20mg $2277.4 Buy

JACOLINE Chemical Properties,Uses,Production

Description

A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D + 48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid, ClOH1S0 7. The latter contains three hydroxyl and three methyl groups.

Uses

Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea).

References

Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959)

JACOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

JACOLINE Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Didu New Materials Co. Ltd
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Amadis Chemical Company Limited
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Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632 sales@reading-chemicals.com China 15178 58
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6905 55
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EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 89686 60
Shenzhen Regent Biochemical Technology Co., Ltd. 0755-85201366 18938635012 sales@regentsciences.com China 9378 58
Nanjing Digger Medical Technology Co. Ltd. 025-025-51191215 18013836722 2399235533@qq.com China 4932 58
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 sales@reading-chemicals.com China 14081 58
JACOLINE Jacolin [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)- (20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione 480-76-2