1,3-oxazinane
- CAS No.
- 14558-49-7
- Chemical Name:
- 1,3-oxazinane
- Synonyms
- 1,3-oxazinane;tetrahydro-2H-1,3-Oxazine;2H-1,3-Oxazine, tetrahydro-
- CBNumber:
- CB61465804
- Molecular Formula:
- C4H9NO
- Molecular Weight:
- 87.12
- MDL Number:
- MFCD13191587
- MOL File:
- 14558-49-7.mol
- MSDS File:
- SDS
| Melting point | 132-133 °C |
|---|---|
| Boiling point | 135-136 °C |
| Density | 0.9920 g/cm3 |
| storage temp. | 2-8°C |
| pka | 8.08±0.20(Predicted) |
| FDA UNII | 2WM6T7ZJ9H |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501 |
1,3-oxazinane price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 292635 | 1,3-Oxazinane | 14558-49-7 | 250.00mg | $100 | 2026-05-19 | Buy |
| Matrix Scientific | 292635 | 1,3-Oxazinane | 14558-49-7 | 1.00g | $230 | 2026-05-19 | Buy |
| Matrix Scientific | 292635 | 1,3-Oxazinane | 14558-49-7 | 5.00g | $804 | 2026-05-19 | Buy |
| Synthonix | X40263 | 1,3-Oxazinane 96% | 14558-49-7 | 100mg | $150 | 2026-05-06 | Buy |
| Synthonix | X40263 | 1,3-Oxazinane 96% | 14558-49-7 | 250mg | $250 | 2026-05-06 | Buy |
1,3-oxazinane Chemical Properties,Uses,Production
Synthesis
50-00-0
156-87-6
14558-49-7
Synthesis of 1,3-oxazinane (41): 3-amino-1-propanol (15 mmol) and paraformaldehyde (15 mmol) were dissolved in 20 mL of anhydrous ethanol. The reaction mixture was stirred at room temperature overnight under nitrogen protection. Upon completion of the reaction, the ethanol solvent was removed by distillation under reduced pressure. Subsequently, the product was subjected to decompression distillation (37-39 °C, 1.2 mmHg) to afford 1,3-oxazinane in the form of a colorless liquid in 57% yield. The structure of the product was confirmed by the following characterization data: 1H NMR (CDCl3) δ 4.29 (s, 2H), 3.79 (t, 2H, J = 5.3 Hz), 2.91 (t, 2H, J = 5.5 Hz), 1.50 (qu, 2H, J = 5.4 Hz); 13C NMR (CDCl3) δ 80.1, 67.7, 44.1, 28.2 ; HRMS (FAB) calculated value C4H10NO ([M + H]+): 88.0756, measured value: 88.0760.
References
[1] Journal of Organic Chemistry, 2008, vol. 73, # 15, p. 5766 - 5775
[2] Patent: WO2008/144933, 2008, A1. Location in patent: Page/Page column 77-78
[3] Recueil des Travaux Chimiques des Pays-Bas, 1959, vol. 78, p. 289,309
1,3-oxazinane Preparation Products And Raw materials
Raw materials
Preparation Products
1,3-oxazinane Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
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| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
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| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Shanghai WangFa Chemical Technology Co., Ltd. | 13918479294 | xiebenfa@163.com | China | 4352 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
