5-METHYL-2-NITROBENZONITRILE
- CAS No.
- 64113-86-6
- Chemical Name:
- 5-METHYL-2-NITROBENZONITRILE
- Synonyms
- 6-nitro-m-tolunitrile;Benzonitrile,5-Methyl-2-nitro-;5-METHYL-2-NITROBENZONITRILE ISO 9001：2015 REACH;Cyclohepta[c]pyrazole-3-carboxylicacid,2,4,5,6,7,11-hexahydro-,ethylester
- CBNumber:
- CB61484878
- Molecular Formula:
- C8H6N2O2
- Molecular Weight:
- 162.15
- MDL Number:
- MFCD00267507
- MOL File:
- 64113-86-6.mol
- MSDS File:
- SDS
5-METHYL-2-NITROBENZONITRILE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M341270 | 5-Methyl-2-nitrobenzonitrile | 64113-86-6 | 250mg | $45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0101468 | 5-METHYL-2-NITROBENZONITRILE 95.00% | 64113-86-6 | 1G | $187.95 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4754-1-0D | 5-Methyl-2-nitrobenzonitrile 95.0% | 64113-86-6 | 5G | $109 | 2021-12-16 | Buy |
| Matrix Scientific | 074354 | 5-Methyl-2-nitrobenzonitrile 95+% | 64113-86-6 | 1g | $347 | 2021-12-16 | Buy |
| AK Scientific | W7590 | 5-Methyl-2-nitrobenzonitrile | 64113-86-6 | 25g | $391 | 2021-12-16 | Buy |
5-METHYL-2-NITROBENZONITRILE Chemical Properties,Uses,Production
Synthesis
4315-12-2
64113-86-6
Phosphorus trichloride (16.96 mL, 1.1 eq.) was slowly added to a solution of N,N-dimethylformamide (329.6 mL) of 5-methyl-2-nitrobenzamide (29.8 g, 0.165 mol) via syringe over a period of 20 minutes. The reaction mixture was stirred at 25 °C for 40 min, followed by heating to 100 °C and continued stirring for 15 min. Upon completion of the reaction, the mixture was slowly poured into ice (750 g) and the pH of the aqueous solution was adjusted to 9-10 with ammonia (75 mL).The aqueous layer was extracted with ethyl acetate (1000 mL, followed by 2 x 600 mL). The organic layers were combined, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford 2-nitro-5-methylbenzonitrile (25.7 g, 96% yield) as a yellow solid, which could be used in subsequent reactions without further purification. The purity of the product was confirmed by 1H NMR: 1H NMR (CDCl3) δ 2.54 (s, 3H, CH3), 7.59 (d, J = 8.4 Hz, 1H, Ar-H), 7.71 (s, 1H, Ar-H), 8.24 (d, J = 8.4 Hz, 1H, Ar-H).
References
[1] Patent: US2004/92739, 2004, A1. Location in patent: Page 4
[2] Patent: US2009/253719, 2009, A1. Location in patent: Page/Page column 19-20
[3] Tetrahedron, 1994, vol. 50, # 18, p. 5515 - 5525
[4] Medicinal Chemistry Research, 1999, vol. 9, # 3, p. 176 - 185
[5] Patent: US2010/260825, 2010, A1. Location in patent: Page/Page column 4
5-METHYL-2-NITROBENZONITRILE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20185 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14360 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 8026 | 58 |
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from 5-METHYL-2-NITROBENZONITRILE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-25 | 6-nitro-m-tolunitrile
64113-86-6
|
US $5.00-0.50 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 6-nitro-m-tolunitrile
64113-86-6
- US $5.00-0.50 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
