Lipid N2-3L
- CAS No.
- 2924606-55-1
- Chemical Name:
- Lipid N2-3L
- Synonyms
- Lipid N2-3L;9-Octadecenoic acid (9Z)-, 3-[2-[(2-hexyl-1-oxodecyl)oxy]ethyl]-14-hydroxy-12-(2-hydroxyethyl)-7-oxo-6-oxa-3,8,12-triazatetradec-1-yl ester
- CBNumber:
- CB615472302
- Molecular Formula:
- C48H93N3O8
- Molecular Weight:
- 840.27
- MDL Number:
- MOL File:
- 2924606-55-1.mol
- MSDS File:
- SDS
Lipid N2-3L price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 40911 | Lipid N2-3L ≥95% | 2924606-55-1 | 1mg | $86 | 2026-04-30 | Buy |
| Cayman Chemical | 40911 | Lipid N2-3L ≥95% | 2924606-55-1 | 5mg | $344 | 2026-04-30 | Buy |
| Cayman Chemical | 40911 | Lipid N2-3L ≥95% | 2924606-55-1 | 10mg | $515 | 2026-04-30 | Buy |
| BroadPharm | bp-42653 | Lipid N2-3L (solution in methyl acetate) | 2924606-55-1 | 1MG | $150 | 2026-05-24 | Buy |
| BroadPharm | bp-42653 | Lipid N2-3L (solution in methyl acetate) | 2924606-55-1 | 5MG | $430 | 2026-05-24 | Buy |
Lipid N2-3L Chemical Properties,Uses,Production
Description
Lipid N2-3L is an ionizable cationic lipid (pKa = 8.99) that has been used in the generation of supramolecular lipid nanoparticles (SMLNPs) encapsulating mRNA for use in vitro and in vivo.1 SMLNPs containing lipid N2-3L and encapsulating a luciferase reporter accumulate at the site of injection and in the draining lymph nodes of mice. Lipid N2-3L-containing SMLNPs encapsulating ovalbumin mRNA and the toll-like receptor 7/8 (TLR7/8) agonist R-848 (Item No. 14806) as an adjuvant promote dendritic cell maturation and antigen presentation, reduce tumor volume, and increase survival in an MC-38-OVA murine model of colon cancer.WARNING This product is not for human or veterinary use.
References
[1] SHAOLONG QI. Supramolecular Lipid Nanoparticles Based on Host–Guest Recognition: A New Generation Delivery System of mRNA Vaccines For Cancer Immunotherapy[J]. Advanced Materials, 2024, 36 23. DOI: 10.1002/adma.202311574
Lipid N2-3L Preparation Products And Raw materials
Raw materials
Preparation Products
Lipid N2-3L Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangdong Fengkang Synthetic Chemical Technology Co., Ltd | 15953196022 | fulkare@163.com | China | 119 | 58 |
| Supplier | Advantage |
|---|---|
| Guangdong Fengkang Synthetic Chemical Technology Co., Ltd | 58 |
