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1,4-Dioxa-8-azaspiro[4.5]decane

CAS No.
177-11-7
Chemical Name:
1,4-Dioxa-8-azaspiro[4.5]decane
Synonyms
4-PIPERIDONE ETHYLENE KETAL;AKOS BBS-00003616;Pibrentasvir Impurity 18;4-Piperidinone ethyl ketal;PIPERIDONE 4-ETHYLENEKETAL;4-PIPERIDONE ETHYLENE ACETAL;4,4-(Ethylenedioxy)piperidine;4-PIPERIDINONE ETHYLENE KETAL;4-Piperidinone ethylene acetal;Piperidin-4-one ethylene ketal
CBNumber:
CB6185484
Molecular Formula:
C7H13NO2
Molecular Weight:
143.18
MDL Number:
MFCD00005976
MOL File:
177-11-7.mol
MSDS File:
SDS
Last updated:2025-07-04 14:23:28
Product description Number Pack Size Price
1,4-Dioxa-8-azaspiro[4.5]decane 98% 178365 10g $43
1,4-Dioxa-8-azaspiro[4.5]decane 98% 178365 50g $177
4-Piperidone Ethyleneketal >98.0%(GC)(T) P2325 5g $29
4-Piperidone Ethyleneketal >98.0%(GC)(T) P2325 25g $82
Piperidin-4-one Ethylene Ketal 165956 1g $496
More product size

1,4-Dioxa-8-azaspiro[4.5]decane Properties

Boiling point 108-111 °C26 mm Hg(lit.)
Density 1.117 g/mL at 20 °C(lit.)
refractive index n20/D 1.4819(lit.)
Flash point 179 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DCM, Ethyl Acetate, Methanol
form Liquid
pka 10.92±0.20(Predicted)
color Clear colorless to yellow
Water Solubility Soluble in water (Partly miscible).
Sensitive Air Sensitive
BRN 506799
InChI InChI=1S/C7H13NO2/c1-3-8-4-2-7(1)9-5-6-10-7/h8H,1-6H2
InChIKey KPKNTUUIEVXMOH-UHFFFAOYSA-N
SMILES O1C2(CCNCC2)OCC1
CAS DataBase Reference 177-11-7(CAS DataBase Reference)
NIST Chemistry Reference 1,4-Dioxa-8-azaspiro(4.5)decane(177-11-7)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  3
10-34
Hazard Note  Irritant
HS Code  29349990
NFPA 704
1
2 0

1,4-Dioxa-8-azaspiro[4.5]decane Chemical Properties,Uses,Production

Chemical Properties

clear colorless to yellowish liquid

Uses

Piperidin-4-one Ethylene Ketal is a derivative formed from the condensation of cyclohexanone.

Uses

1,4-Dioxa-8-azaspiro[4.5]decane was used in the synthesis of 1,4-dioxa-8-azaspiro [4,5] deca spirocyclotriphosphazenes.

5625-67-2
915702-47-5
177-11-7
Synthesis of 1,4-Dioxa-8-azaspiro[4.5]decane from 2-Piperazinone and [4,5'-Bithiazole]-2-carbonyl chloride, 2'-(acetylamino)-4'-methyl-
4,4-(Ethylenedioxy)piperidine 4-Piperidinone ethylene acetal 8-Aza-1,4-dioxaspiro[4.5]decane Piperidin-4-one ethylene ketal Piperidine-4-one ethylene acetal Spiro[piperidine-4,2'-[1,3]dioxolane] 1,4-DIOXA-8-AZASPIRO[4.5]DECANE 4-Piperidone ethylene ketal, 98+% 4-Piperidone ethylene ketal 98% 1,4-DIOXA-8-AZASPIRO(4.5)DECANE (4-PIPERIDONE ETHYLENE KETAL) 1,4-dioxa-8-azoniaspiro[4.5]decane 1,4-Dioxa-8-azaspiro(4 x 5)decane (4-Piperidone ethylene ketal) 1,4-Dioxa-8-azaspiro[4.5]decane, 98% 10GR 1,4-Dioxa-8-azaspiro[4.5]decane, 98% 50GR 1,4-Dioxa-8-azaspiro[4.5]decane,98% 1,4-Dioxa-8-azaspiro(4.5)decan 1,4-Dioxa-8-azaspiro[4.5]decane ,99% 8-Aza-1,4-dioxaspiro[4.5]decane 98% 1,4-Dioxa-8-azaspiro[4.5]decane1,4-Dioxa-8-azaspiro[4.5]decane 8-Aza-1,4-dioxaspiro[4.5]decane98% 4-Piperidinone ethyl ketal PIPERIDONE 4-ETHYLENEKETAL 4-PIPERIDONE ETHYLENE ACETAL 4-PIPERIDONE ETHYLENE KETAL 4-PIPERIDINONE ETHYLENE KETAL AKOS BBS-00003616 4-PIPERII)ONE ETHYLENE KETAL (or) 1,4 DIOXA 8-AZASPIRO [4,5] DECANE CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane 1,4-dioxa-8-azaspiro[4.5]decan-8-ium 1,4-Dioxa-8-azaspiro[4.5]decane (7CI, 8CI, 9CI, ACI) Pibrentasvir Impurity 18 1,4-Dioxa-8-azaspiro[4.5]decane - [P13574] 177-11-7 177-1-7 1051011-13-7 117-11-7 2077-11-7 Piperidones Heterocyclic Building Blocks Building Blocks AMINE Building Blocks Chemical Synthesis Heterocyclic Building Blocks Piperidones Piperidine john's