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1,4-Dioxa-8-azaspiro[4.5]decane

1,4-Dioxa-8-azaspiro[4.5]decane structure

CAS No.: 177-11-7

Chemical Name:: 1,4-Dioxa-8-azaspiro[4.5]decane

Synonyms: 4-PIPERIDONE ETHYLENE KETAL;8-Aza-1,4-dioxaspiro[4.5]decane;4-PIPERIDONE ETHYLENE ACETAL;AKOS BBS-00003616;Pibrentasvir Impurity 18;4-Piperidinone ethyl ketal;PIPERIDONE 4-ETHYLENEKETAL;4-Piperidone ethylene glycol;4,4-(Ethylenedioxy)piperidine;4-PIPERIDINONE ETHYLENE KETAL

CBNumber:: CB6185484

Molecular Formula:: C7H13NO2

Molecular Weight:: 143.18

MDL Number:: MFCD00005976

MOL File:: 177-11-7.mol

MSDS File:: SDS

Last updated:2026-05-28 02:16:47

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1,4-Dioxa-8-azaspiro[4.5]decane Properties

Boiling point	108-111 °C26 mm Hg(lit.)
Density	1.117 g/mL at 20 °C(lit.)
refractive index	n20/D 1.4819(lit.)
Flash point	179 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DCM, Ethyl Acetate, Methanol
form	Liquid
pka	10.92±0.20(Predicted)
color	Clear colorless to yellow
Water Solubility	Soluble in water (Partly miscible).
Sensitive	Air Sensitive
BRN	506799
InChI	InChI=1S/C7H13NO2/c1-3-8-4-2-7(1)9-5-6-10-7/h8H,1-6H2
InChIKey	KPKNTUUIEVXMOH-UHFFFAOYSA-N
SMILES	O1C2(CCNCC2)OCC1
CAS DataBase Reference	177-11-7(CAS DataBase Reference)
NIST Chemistry Reference	1,4-Dioxa-8-azaspiro(4.5)decane(177-11-7)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-24/25

WGK Germany

10-34

Hazard Note

Irritant

HS Code

29349990

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

1,4-Dioxa-8-azaspiro[4.5]decane price More Price(50)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	178365	1,4-Dioxa-8-azaspiro[4.5]decane 98%	177-11-7	10g	$43	2023-06-20	Buy
Sigma-Aldrich	178365	1,4-Dioxa-8-azaspiro[4.5]decane 98%	177-11-7	50g	$177	2023-06-20	Buy
TCI Chemical	P2325	4-Piperidone Ethyleneketal >98.0%(GC)(T)	177-11-7	5g	$29	2024-03-01	Buy
TCI Chemical	P2325	4-Piperidone Ethyleneketal >98.0%(GC)(T)	177-11-7	25g	$82	2024-03-01	Buy
Apolloscientific	OR6940	8-Aza-1,4-dioxaspiro[4.5]decane ≥97%	177-11-7	5g	$21	2026-06-04	Buy

Product number	Packaging	Price	Buy
178365	10g	$43	Buy
178365	50g	$177	Buy
P2325	5g	$29	Buy
P2325	25g	$82	Buy
OR6940	5g	$21	Buy

1,4-Dioxa-8-azaspiro[4.5]decane Chemical Properties, Uses, Production

Chemical Properties

clear colorless to yellowish liquid

Uses

Piperidin-4-one Ethylene Ketal is a derivative formed from the condensation of cyclohexanone.

Uses

1,4-Dioxa-8-azaspiro[4.5]decane was used in the synthesis of 1,4-dioxa-8-azaspiro [4,5] deca spirocyclotriphosphazenes.

1,4-Dioxa-8-azaspiro[4.5]decane synthesis

Synthesis of 1,4-Dioxa-8-azaspiro[4.5]decane from 2-Piperazinone and [4,5'-Bithiazole]-2-carbonyl chloride, 2'-(acetylamino)-4'-methyl-

1,4-Dioxa-8-azaspiro[4.5]decane Preparation Products And Raw materials

Raw materials

p-Toluenesulfonic acid Hexane Sodium sulfate Diethyl ether Benzene

Ethyl acetate Sodium bicarbonate Ethylene glycol 4-Piperidinone

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Preparation Products

(1-Benzylpiperidin-4-ylidene)acetic acid ethyl ester N-Acetyl-4-piperidone Pazinaclone 1,4-Dioxa-8-azaspiro[4.5]decane, 8-acetyl- (9CI) 8-Phenethyl-1,4-dioxa-8-aza-spiro[4.5]decane

1-(4-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)phenyl)ethanone

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1,4-Dioxa-8-azaspiro[4.5]decane Spectrum

1,4-Dioxa-8-azaspiro[4.5]decane(177-11-7)¹HNMR 1,4-Dioxa-8-azaspiro[4.5]decane(177-11-7)FT-IR 1,4-Dioxa-8-azaspiro[4.5]decane(177-11-7)IR 1,4-Dioxa-8-azaspiro[4.5]decane(177-11-7)Raman

177-11-7 (1,4-Dioxa-8-azaspiro[4.5]decane) Related Search:

ETHYLENE Decane Haloperidol Ethylene thiourea Diethylene glycol

Triethylene glycol Thalidomide 2-Bromomethyl-1,3-dioxolane Polyethylene Ethylene glycol

Ethylene oxide Pazinaclone Cronidipine 4-Piperidinone 1-Nonene

4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-1,1,1-trifluoro-butan-2-ol 8-Phenethyl-1,4-dioxa-8-aza-spiro[4.5]decane 7,7,9,9-Tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane-2-methanol

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4,4-(Ethylenedioxy)piperidine 4-Piperidinone ethylene acetal Piperidin-4-one ethylene ketal Piperidine-4-one ethylene acetal Spiro[piperidine-4,2'-[1,3]dioxolane] 1,4-DIOXA-8-AZASPIRO[4.5]DECANE 4-Piperidone ethylene ketal, 98+% 4-Piperidone ethylene ketal 98% 1,4-DIOXA-8-AZASPIRO(4.5)DECANE (4-PIPERIDONE ETHYLENE KETAL) 1,4-dioxa-8-azoniaspiro[4.5]decane 1,4-Dioxa-8-azaspiro(4 x 5)decane (4-Piperidone ethylene ketal) 1,4-Dioxa-8-azaspiro[4.5]decane, 98% 10GR 1,4-Dioxa-8-azaspiro[4.5]decane, 98% 50GR 1,4-Dioxa-8-azaspiro[4.5]decane,98% 1,4-Dioxa-8-azaspiro(4.5)decan 1,4-Dioxa-8-azaspiro[4.5]decane ,99% 8-Aza-1,4-dioxaspiro[4.5]decane 98% 1,4-Dioxa-8-azaspiro[4.5]decane1,4-Dioxa-8-azaspiro[4.5]decane 8-Aza-1,4-dioxaspiro[4.5]decane98% 4-Piperidinone ethyl ketal PIPERIDONE 4-ETHYLENEKETAL 4-PIPERIDINONE ETHYLENE KETAL AKOS BBS-00003616 4-PIPERII)ONE ETHYLENE KETAL (or) 1,4 DIOXA 8-AZASPIRO [4,5] DECANE CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane 1,4-dioxa-8-azaspiro[4.5]decan-8-ium 1,4-Dioxa-8-azaspiro[4.5]decane (7CI, 8CI, 9CI, ACI) Pibrentasvir Impurity 18 1,4-Dioxa-8-azaspiro[4.5]decane - [P13574] 4-PIPERIDONE ETHYLENE ACETAL 4-PIPERIDONE ETHYLENE KETAL 8-Aza-1,4-dioxaspiro[4.5]decane 4-Piperidone ethylene glycol 177-11-7 177-1-7 1051011-13-7 117-11-7 2077-11-7 Piperidones Heterocyclic Building Blocks Building Blocks AMINE Building Blocks Chemical Synthesis Heterocyclic Building Blocks Piperidones Piperidine john's