Exendin (5-39)
- CAS No.
- 196109-27-0
- Chemical Name:
- Exendin (5-39)
- Synonyms
- Exendin (5-39);Exendin4(5-39);Exendin 4 (5-39)amide;THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
- CBNumber:
- CB6186087
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01634833
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
Exendin (5-39) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | PEX-4345-V | Exendin (5-39) | 0.5mg | $1253.33 | 2026-06-04 | Buy | |
| ChemScene | CS-0135041 | Exendin 5-39 99.43% | 196109-27-0 | 1mg | $125 | 2026-06-04 | Buy |
| ChemScene | CS-0135041 | Exendin 5-39 99.43% | 196109-27-0 | 5mg | $303 | 2026-06-04 | Buy |
| ChemScene | CS-0135041 | Exendin 5-39 99.43% | 196109-27-0 | 10mg | $487 | 2026-06-04 | Buy |
| aablocks | AA02509D | Exendin (5-39) >98% | 196109-27-0 | 1mg | $163 | 2026-06-01 | Buy |
Exendin (5-39) Chemical Properties, Uses, Production
Uses
Exendin (5-39) is a potent glucagon-like peptide 1 (GLP-1) receptor antagonist. Exendin (5-39) improves memory impairment in β-amyloid protein-treated rats[1].
in vivo
Exendin (5-39) (intracerebroventricular injection; 0.3 μg; once daily; 1-week) increases GLT-1 protein levels in the hippocampus of male Wistar rats. Additionally, hippocampal slices are prepared from Ex-treated or vehicle rats,Exendin (5-39) decreases fEPSP decay time and increases the input-output relation and decreased the paired-pulse ratio in the dentate gyrus (DG). Furthermore, Ex inhibits long-term depression but not long-term potentiation in the DG[1].
| Animal Model: | Wistar rats (3 weeks old and 18 days pregnant)[1] |
| Dosage: | 0.3 μg |
| Administration: | Intracerebroventricular injection; 0.3 μg; once daily; 1-week |
| Result: | Inhibited GLT-1 protein levels and inhibited long-term depression in rats. |
References
[1] Kazuma Kobayashi, et al. Exendin (5-39), an antagonist of GLP-1 receptor, modulates synaptic transmission via glutamate uptake in the dentate gyrus. Brain Res. 2013 Apr 10;1505:1-10. DOI:10.1016/j.brainres.2013.01.012
Exendin (5-39) Preparation Products And Raw materials
Raw materials
Preparation Products
Exendin (5-39) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 7446 | 58 |
| Shanghai?Medlife?Pharm-Tech?Co.,?Ltd | 4000862158 18117107507 | vip@med-life.cn | China | 4999 | 58 |
| Hangzhou ALLPEPTIDE Biotechnology Co., Ltd. | 17342063383 | sales@allpeptide.com | China | 5319 | 58 |
| YantaiBio | 13758194781; 13758194781 | 764619768@qq.com | China | 1773 | 58 |
| Fuan Bio | 15002819872 | 2845971812@qq.com | China | 2103 | 58 |
| LEON (NANJING) BIOTECHNOLOGY CO., LTD. | 15051830413 | sales.njleonbiotech@gmail.com | China | 5482 | 58 |
