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Pentafluorobenzoyl chloride

CAS No.
2251-50-5
Chemical Name:
Pentafluorobenzoyl chloride
Synonyms
2,3,4,5,6-PENTAFLUOROBENZOYL CHLORIDE;PERFLUOROBENZOYL CHLORIDE;pentafluorobenzoychloride;SKL1300;NSC 97002;Pentafluorobenzoyl c;pentaflurobenzyl cyanide;PENTAFLUOROBENZOYL CHLORIDE;Pentafluorobenzoylchloride99%;PentafluorobenzoylChloride>
CBNumber:
CB6191348
Molecular Formula:
C7ClF5O
Molecular Weight:
230.52
MDL Number:
MFCD00000657
MOL File:
2251-50-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:29:19
Product description Number Pack Size Price
Pentafluorobenzoyl chloride for synthesis 8.41331 5ML $88.7
2,3,4,5,6-Pentafluorobenzoyl chloride 99% 103772 1g $37.9
Pentafluorobenzoyl chloride for synthesis 8.41331 25ML $322
2,3,4,5,6-Pentafluorobenzoyl chloride 99% 103772 5g $81.4
Pentafluorobenzoyl Chloride >98.0%(GC)(T) P0807 5g $79
More product size

Pentafluorobenzoyl chloride Properties

Boiling point 158-159 °C(lit.)
Density 1.601 g/mL at 25 °C(lit.)
refractive index n20/D 1.453(lit.)
Flash point None
storage temp. Store below +30°C.
solubility soluble in Chloroform
form Liquid
Specific Gravity 1.601
color Clear colorless to light yellow
Water Solubility decomposes
Sensitive Lachrymatory
BRN 2054397
Stability Moisture Sensitive
InChI 1S/C7ClF5O/c8-7(14)1-2(9)4(11)6(13)5(12)3(1)10
InChIKey MYHOHFDYWMPGJY-UHFFFAOYSA-N
SMILES Fc1c(F)c(F)c(c(F)c1F)C(Cl)=O
CAS DataBase Reference 2251-50-5(CAS DataBase Reference)
FDA UNII 4RXU8P4SDS
NIST Chemistry Reference Pentafluorobenzoyl chloride(2251-50-5)
UNSPSC Code 12352106
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  14-34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
10-19-21
Hazard Note  Corrosive/Lachrymator
HazardClass  8
PackingGroup  II
HS Code  29163900
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
0
3 0
W

Pentafluorobenzoyl chloride price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.41331 Pentafluorobenzoyl chloride for synthesis 2251-50-5 5ML $88.7 2026-04-30 Buy
Sigma-Aldrich 103772 2,3,4,5,6-Pentafluorobenzoyl chloride 99% 2251-50-5 1g $37.9 2026-04-30 Buy
Sigma-Aldrich 8.41331 Pentafluorobenzoyl chloride for synthesis 2251-50-5 25ML $322 2026-04-30 Buy
Sigma-Aldrich 103772 2,3,4,5,6-Pentafluorobenzoyl chloride 99% 2251-50-5 5g $81.4 2026-04-30 Buy
TCI Chemical P0807 Pentafluorobenzoyl Chloride >98.0%(GC)(T) 2251-50-5 5g $79 2026-04-30 Buy
Product number Packaging Price Buy
8.41331 5ML $88.7 Buy
103772 1g $37.9 Buy
8.41331 25ML $322 Buy
103772 5g $81.4 Buy
P0807 5g $79 Buy

Pentafluorobenzoyl chloride Chemical Properties,Uses,Production

Description

Pentafluorobenzoyl chloride is the acid chloride of pentafluorobenzoic acid. It is a sensitive derivatising reagent for the analysis of amines, amides and phenols by electron capture gas chromatography. It has a role as a chromatographic reagent. It is an acyl chloride and a perfluorinated compound. It derives from a pentafluorobenzoic acid.
2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivatize dimethylamine(DMA) in study to develop a rapid and accurate GC–MS method for determination of DMA in human urine. 2,3,4,5,6-Pentafluorobenzoyl chloride was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry.

Chemical Properties

clear colorless to light yellow liquid

Uses

Pentafluorobenzoyl Chloride is a useful analytical reagent in the derivatization amphetamines as well as other primary amines.

Uses

A reagent used for deriving primary amines. 2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivative dimethylamine(DMA) in study to develop a rapid and accurate GC-MS method for determination of DMA in human urine. It was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry.

Uses

Pentafluorobenzoyl chloride can be used for the derivatization of a variety of analytes including biological amines. There is an extensive use for the derivatization of lipids.

Definition

ChEBI: The acid chloride of pentafluorobenzoic acid. It is a sensitive derivatising reagent for the analysis of amines, amides and phenols by electron capture gas chromatography.

602-94-8
2251-50-5
Synthesis of Pentafluorobenzoyl chloride from Pentafluorobenzoic acid

Pentafluorobenzoyl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 264)Suppliers
Supplier Tel Email Country ProdList Advantage
NANJING ACE CHEMICAL CO.,LTD
+8618268053070 e.wen@ace-chemical.com China 8 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
Hi-Tech Chemistry Corp
0519-86626038 yuhh@hitechem.com CHINA 810 58
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Fluoropharm Co., Ltd.
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career henan chemical co
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Changzhou Ansciep Chemical Co., Ltd.
+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618 sales@amoychem.com China 6366 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58

View Lastest Price from Pentafluorobenzoyl chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pentafluorobenzoyl chloride pictures 2026-03-26 Pentafluorobenzoyl chloride
2251-50-5
1KG 99% 50TONS NANJING ACE CHEMICAL CO.,LTD
Pentafluorobenzoyl chloride pictures 2025-09-25 Pentafluorobenzoyl chloride
2251-50-5
$8.00 1KG 99% Henan Fengda Chemical Co., Ltd
Pentafluorobenzoyl chloride pictures 2025-04-04 Pentafluorobenzoyl chloride
2251-50-5
1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
Benzoyl chloride, pentafluoro- PENTAFLUOROBENZOIC ACID CHLORIDE PENTAFLUOROBENZOYL CHLORIDE PERFLUOROBENZOYL CHLORIDE 2,3,4,5,6-PENTAFLUOROBENZOYL CHLORIDE SE T WITH 10 X 1 ML pentaflurobenzyl cyanide Pentafluorobenzoyl chloride 99% Pentafluorobenzoylchloride99% Pentafluorobenzoic acid chloride, Perfluorobenzoyl chloride 2,3,4,5,6-Pentafluorobenzoic acid chloride 2,3,4,5,6-Pentafluorobenzoyl chloride 99% Pentafluorobenzoyl chloride SynonyMs 2,3,4,5,6-Pentafluorobenzylchloride 2,3,4,5,6-Pentafluorobenzoyl choride Pentafluorobenzoyl chloride for synthesis Pentafluorobenzoyl c Pentafluorobenzoyl chloride, 98% 5GR NSC 97002 Pentafluorobenzoyl chloride,98% 2,3,4,5,6-Pentafluorobenzoychloride pentafluorobenzoychloride PentafluorobenzoylChloride> PENTAFLUOROBENZOYL CHLORIDE FOR SYNTHESI Benzoyl chloride, 2,3,4,5,6-pentafluoro- Pentafluorobenzoyl chloride ISO 9001:2015 REACH SKL1300 2.3.45,6-Penta-fluorabenzoy-chloride 2,3,4,5,6-PENTAFLUOROBENZOYL CHLORIDE 2251-50-5 2251-23-8 C7ClF5O C6F5COCl C7Cl1F5O C12H32N6O2 Acylation (GC Derivatizing Reagents) GC Derivatizing Reagents Fluorine series Acylation (GC Derivatizing Reagents) Analytical Chemistry GC Derivatizing Reagents Pyridines