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2-Methoxy-5-methylaniline

CAS No.
120-71-8
Chemical Name:
2-Methoxy-5-methylaniline
Synonyms
PARA CRESIDINE;P-CRESIDINE;CRESIDINE;5-METHYL-O-ANISIDINE;6-METHOXY-M-TOLUIDINE;2-Methoxy-5-methylbenzenamine;6-methoxy-m-toluidine p-cresidine;2-Methoxy-5-methylaniline,5-Methyl-o-anisidine, 6-Methoxy-m-toluidine, p-Cresidine;Kresidin;Krezidin
CBNumber:
CB6191898
Molecular Formula:
C8H11NO
Molecular Weight:
137.18
MDL Number:
MFCD00007815
MOL File:
120-71-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:29:20
Product description Number Pack Size Price
2-Methoxy-5-methylaniline 99% 103284 100g $145
2-Methoxy-5-methylaniline 99% 103284 500g $435
2-Methoxy-5-methylaniline >98.0%(GC)(T) M0115 25g $25
2-Methoxy-5-methylaniline >98.0%(GC)(T) M0115 500g $201
p-Cresidine 165781 10g $326
More product size

2-Methoxy-5-methylaniline Properties

Melting point 50-52 °C (lit.)
Boiling point 235 °C (lit.)
Density 1.0252 (rough estimate)
vapor density 4.7 (vs air)
vapor pressure 2.6Pa at 20℃
refractive index 1.5647 (estimate)
Flash point >230 °F
storage temp. Room Temperature, under inert atmosphere
solubility Chloroform (Slightly), Ethyl Acetate, Methanol (Slightly)
form Crystalline Chunks
pka 4.66±0.10(Predicted)
color Brown to black
Water Solubility Slightly soluble in hot water.
BRN 637071
Henry's Law Constant 8.0×101 mol/(m3Pa) at 25℃, HSDB (2015)
Stability Air Sensitive
Major Application cleaning products
cosmetics
environmental
food and beverages
personal care
InChI 1S/C8H11NO/c1-6-3-4-8(10-2)7(9)5-6/h3-5H,9H2,1-2H3
InChIKey WXWCDTXEKCVRRO-UHFFFAOYSA-N
SMILES COc1ccc(C)cc1N
LogP 1.65 at 23℃ and pH7
Toxicology and Carcinogenesis Bioassay of p-Cresidine for Possible Carcinogenicity (CASRN 120-71-8)
Substances of Very High Concern (SVHC) Candidate List 6-methoxy-m-toluidine (p-cresidine) (120-71-8)
CAS DataBase Reference 120-71-8(CAS DataBase Reference)
EWG's Food Scores 3
FDA UNII 4C11L78UR3
Proposition 65 List p-Cresidine
NIST Chemistry Reference Benzenamine, 2-methoxy-5-methyl-(120-71-8)
IARC 2B (Vol. 27, Sup 7) 1987
EPA Substance Registry System p-Cresidine (120-71-8)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H315-H319-H371-H341-H351
Precautionary statements  P501-P260-P270-P202-P201-P264-P280-P302+P352-P337+P313-P305+P351+P338-P308+P311-P362+P364-P332+P313-P301+P312+P330-P405
PPE Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes  T,Xi
Risk Statements  45-22
Safety Statements  53-45
WGK Germany  3
RTECS  BZ6720000
9
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29222990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 4 Oral
Carc. 1B
Eye Irrit. 2
Hazardous Substances Data 120-71-8(Hazardous Substances Data)
Toxicity rat,LD50,oral,1450mg/kg (1450mg/kg),Huntingdon Research Center Reports. Vol. -, Pg. -, 1972.
REACH Registrations Active
NFPA 704
1
2 0

2-Methoxy-5-methylaniline price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 103284 2-Methoxy-5-methylaniline 99% 120-71-8 100g $145 2026-04-30 Buy
Sigma-Aldrich 103284 2-Methoxy-5-methylaniline 99% 120-71-8 500g $435 2023-06-20 Buy
TCI Chemical M0115 2-Methoxy-5-methylaniline >98.0%(GC)(T) 120-71-8 25g $25 2026-04-30 Buy
TCI Chemical M0115 2-Methoxy-5-methylaniline >98.0%(GC)(T) 120-71-8 500g $201 2026-04-30 Buy
Usbiological 165781 p-Cresidine 120-71-8 10g $326 2026-06-03 Buy
Product number Packaging Price Buy
103284 100g $145 Buy
103284 500g $435 Buy
M0115 25g $25 Buy
M0115 500g $201 Buy
165781 10g $326 Buy

2-Methoxy-5-methylaniline Chemical Properties,Uses,Production

Description

p-Cresidine is a white crystalline solid.Molecular weight =137.20. Boiling point =235℃;Freezing/Melting point = 52℃; Flash point $ 112℃;Autoignition temperature =450℃. Hazard Identification(based on NFPA-704 M Rating System): Health 2,Flammability 1, Reactivity 0. Practically insoluble in water.

Chemical Properties

brown to black crystalline chunks

Chemical Properties

p-Cresidine is a white crystalline solid.

Uses

p-Cresidine is a reagent used in the preparation of enaminones acting as anticonvulsants. Also used in the preparation of crescent oligoamides. Dyes and metabolites, Environmental Testing.

Uses

2-Methoxy-5-methylaniline was used in the synthesis of 4-(4-Amino-5-methoxy-2-methylphenylazo)-5-hydroxy-naphthalene-2,7-disulfonic acid. 2-Methoxy-5-methylaniline was used to analyse the application of polymeric ionic liquids as selective solid-phase microextraction sorbent coatings for the analysis of genotoxic impurities and structurally alerting compounds such as alkyl halides and aromatics. 2-Methoxy-5-methylaniline was used in a study to develop a sensitive analytical method for the determination of aromatic amines found in commercial hair dyes using high liquid chromatography coupled to an electrochemical detector by using the ionic liquid 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide in the mobile phase.

Definition

ChEBI: Para-Cresidine is a member of methoxybenzenes.

General Description

White to silver-gray odorless crystals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Methoxy-5-methylaniline is sensitive to moisture and temperatures greater than 104°F. Incompatible with strong oxidizing agents .

Hazard

A possible carcinogen.

Fire Hazard

2-Methoxy-5-methylaniline is nonflammable.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Moderately toxic by ingestion. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also ESTERS.

Potential Exposure

p-Cresidine is used as an intermediate in the production of various azodyes, printing inks, and pigments; including 11 dyes that are produced commercially in the United States. Human exposure to p-Cresidine occurs primarily through inhalation of

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
Note to physician: Treat for methemoglobinemia.Spectrophotometry may be required for precise determination of levels of methemoglobinemia in urine.

Carcinogenicity

p-Cresidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

storage

Color Code—Blue (potential carcinogen): HealthHazard/Poison: Store in a secure poison location. Prior toworking with this chemical you should be trained on itsproper handling and storage. Before entering confined spacewhere this chemical may be present, check to make surethat an explosive concentration does not exist. Store intightly closed containers in a cool, well-ventilated areaaway from oxidizers. Store in a refrigerator under an inertatmosphere for prolonged storage. A regulated, marked areashould be established where this chemical is handled, used,or stored in compliance with OSHA Standard 1910.1045.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Global( 287)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co,.LTD
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Henan Tianfu Chemical Co.,Ltd.
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Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
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SIMAGCHEM CORP
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View Lastest Price from 2-Methoxy-5-methylaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methoxy-5-Methylaniline pictures 2026-05-28 2-Methoxy-5-Methylaniline
120-71-8
$10.00 1kg 98% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
2-Methoxy-5-methylaniline pictures 2025-06-20 2-Methoxy-5-methylaniline
120-71-8
$3.00-40.00 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
2-Methoxy-5-methylaniline  120-71-8  p-Cresidine pictures 2020-06-02 2-Methoxy-5-methylaniline 120-71-8 p-Cresidine
120-71-8
1KG 99.50% in stock 550.00 MT per month Chemwill Asia Co.,Ltd.
2-Amino-4-methylphenolmethylether 2-Amino-p-cresol methyl ether 2-Amino-p-cresolmethylether m-amino-p-cresol,methylester meta-amino-para-cresol,methylether NCI-C02982 o-Anisidine, 5-methyl- o-anisidine,5-methyl-(8ci) p-Kresidin 5-METHYL-2-ANISIDINE 2-Methoxy-5-me p-Cresidine Solution, 100ppm 5-Methyl-o-anisidine (NH2=1) 5-Methyl-2-methoxyaniline 6-methoxy-m-toluidine p-cresidine 5-Methyl-o-anisidine, 6-Methoxy-m-toluidine, p-Cresidine Kresidin 2-Methoxy-5-methylaniline,99% 2-Methoxy-5-methylaniline,95% 2-Methoxy-5-methylaniline 1g [120-71-8] 2-Methoxy-5-methylan BenzenaMine, 2-Methoxy-5-Methyl- 2-Methoxy-5-Methylaniline, 95% 5GR 6-METHOXY-META-TOLUIDINE 2-METHOXY-5-METHYLANILINE / 5-METHYL-O-ANISIDINE p-Cresidine 6-Methoxy-m-toluidine 5-Methyl-o-anisidine 5-Methyl-o-anisidine 6-Methoxy-m-toluidine p-Cresidine Cresidine 2-Methoxy-5-methyl-phenylamine 2-Methoxy-5-methyL 2-Methoxy-5-methylaniline 120-71-8 p-Cresidine p-Cresidine 120-71-8 2-Methoxy-5-methylaniline 2-methoxy-5-methyl-benzenamin 2-Methoxy-5-methylbenzenamine 2-methoxy-5-methyl-Benzenamine 1-AMINO-2-METHOXY-5-METHYLBENZENE LABOTEST-BB LTBB000667 c.i. azoic red 83 CRESIDINE 3-amino-para-cresol,methylether 4-Methyl-2-aminoanisole 5-methyl-o-anisidin 5-methyl-ortho-anisidin Azoic red 36 azoicred36 Krezidin Krezidine m-Amino-p-cresol, methyl ester 2-AMINO-4-METHYLANISOLE 2-METHOXY-5-METHYLANILINE 3-Methyl-6-methoxyaniline 5-Methyl-o-anisidine 3-AMINO-P-CRESOL METHYL ETHER 3-AMINO-4-METHOXYTOLUENE 4-METHOXY-M-TOLUIDINE 4-METHOXY-3-AMINO TOLUENE 4-METHYL-O-ANISIDINE PARA CRESIDINE REGULAR 4-METHOXY-2-METHYLANILINE 98% 4-Cresidine98.5%