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2-Bromo-4-chlorophenol

CAS No.
695-96-5
Chemical Name:
2-Bromo-4-chlorophenol
Synonyms
O-broMo-chloro-phenol;2-BROMO-4-CHLOROPHENOL;Phenol, 2-bromo-4-chloro-;2-Bromo-4-chlorophenol 98%;2-Bromo-4-chlorophenol >2-Bromo-4-chlorophenol, 98+%;2-Bromo-4-chlorophenol, 99+%;2-BroMo-4-chlorophenol, 99+% 25GR;2-Bromo-4-chlorophenol,695-96-5,OLED Intermediates,organic synthetic intermediate
CBNumber:
CB6215851
Molecular Formula:
C6H4BrClO
Molecular Weight:
207.45
MDL Number:
MFCD00002319
MOL File:
695-96-5.mol
MSDS File:
SDS
Last updated:2026-05-28 03:07:15
Product description Number Pack Size Price
2-Bromo-4-chlorophenol 98% B62005 25g $96.1
2-Bromo-4-chlorophenol >98.0%(GC) B1522 25g $41
2-Bromo-4-chlorophenol Asreported 264070 25g $336
2-Bromo-4-chlorophenol Asreported 264070 50g $460
2-Bromo-4-chlorophenol Asreported 264070 100g $573
More product size

2-Bromo-4-chlorophenol Properties

Melting point 31-33 °C (lit.)
Boiling point 121-123 °C/10 mmHg (lit.)
Density 1.6027 (rough estimate)
refractive index 1.5730 (estimate)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility methanol: 0.1 g/mL, clear
pka 7.98±0.18(Predicted)
form powder to lump to clear liquid
color White or Colorles to Yellow to Orange
BRN 2042871
InChI InChI=1S/C6H4BrClO/c7-5-3-4(8)1-2-6(5)9/h1-3,9H
InChIKey ZIYRDJLAJYTELF-UHFFFAOYSA-N
SMILES C1(O)=CC=C(Cl)C=C1Br
CAS DataBase Reference 695-96-5(CAS DataBase Reference)
NIST Chemistry Reference Phenol, 2-bromo-4-chloro-(695-96-5)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-28-36/39-24/25
RIDADR  UN 2020 6.1/PG 3
WGK Germany  3
HazardClass  IRRITANT
HS Code  29081000
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
3 0

2-Bromo-4-chlorophenol price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B62005 2-Bromo-4-chlorophenol 98% 695-96-5 25g $96.1 2023-01-07 Buy
TCI Chemical B1522 2-Bromo-4-chlorophenol >98.0%(GC) 695-96-5 25g $41 2026-04-30 Buy
Usbiological 264070 2-Bromo-4-chlorophenol Asreported 695-96-5 25g $336 2026-06-03 Buy
Usbiological 264070 2-Bromo-4-chlorophenol Asreported 695-96-5 50g $460 2026-06-03 Buy
Usbiological 264070 2-Bromo-4-chlorophenol Asreported 695-96-5 100g $573 2026-06-03 Buy
Product number Packaging Price Buy
B62005 25g $96.1 Buy
B1522 25g $41 Buy
264070 25g $336 Buy
264070 50g $460 Buy
264070 100g $573 Buy

2-Bromo-4-chlorophenol Chemical Properties,Uses,Production

Chemical Properties

White to slightly beige low melting solid

Uses

2-Bromo-4-chlorophenol is a reactant in the preparation of 3-(2-(2,4-dichlorophenoxy)ethoxy)-6-methyl-2-nitropyridine selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonist.

Application

The main use of 2-bromo-4-chlorophenol in the pesticide field is as a key intermediate in the synthesis of profenofos. Profenofos is a highly effective broad-spectrum organophosphorus insecticide with contact and stomach poison effects, and also possesses some fumigation activity. It is widely used to control various pests on crops such as cotton and vegetables.

Synthesis

(4-chlorophenoxy)trimethylsilane

17005-59-3

2-Bromo-4-chlorophenol

695-96-5

The general procedure for the synthesis of 2-bromo-4-chlorophenol from the compound (CAS:17005-59-3) is as follows: in a 10 mL round-bottomed flask with a magnetic stir bar, phenols or olefins (0.1 mmol), carbon tetrabromide (CBr4, 33 mg, 0.1 mmol), anhydrous acetonitrile (CH3CN, 1 mL), and dichloro tris(2,2'-) bipyridine)ruthenium(II) (Ru(bpy)3Cl2, 3.8 mg, 0.005 mmol). The reaction mixture was irradiated at room temperature using a blue LED lamp (1 W) and air was continuously passed until the complete disappearance of the raw material was shown by thin layer chromatography (TLC). After completion of the reaction, the solvent was removed by distillation under reduced pressure. Finally, the residue was purified by fast column chromatography to obtain the target product 2-bromo-4-chlorophenol.

References

[1] Beilstein Journal of Organic Chemistry, 2014, vol. 10, p. 622 - 627

95-56-7
695-96-5
2040-88-2
Synthesis of 2-Bromo-4-chlorophenol from 2-Bromophenol
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View Lastest Price from 2-Bromo-4-chlorophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-4-chlorophenol pictures 2026-08-17 2-Bromo-4-chlorophenol
695-96-5
$1.20-34.00 1kg 99% Henan Fengda Chemical Co., Ltd
2-Bromo-4-chlorophenol pictures 2026-04-27 2-Bromo-4-chlorophenol
695-96-5
1kg 98% 100tons Shandong Vital Biotechnology Co., Ltd.
2-Bromo-4-chlorophenol pictures 2025-06-27 2-Bromo-4-chlorophenol
695-96-5
1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
2-Bromo-4-chlorophenol, 99+% 2-BROMO-4-CHLOROPHENOL 2-Bromo-4-chlorophenol, 98+% Phenol, 2-bromo-4-chloro- 2-Bromo-4-chlorophenol 98% O-broMo-chloro-phenol 2-BroMo-4-chlorophenol, 99+% 25GR 2-Bromo-4-chlorophenol > 2-Bromo-4-chlorophenol,695-96-5,OLED Intermediates,organic synthetic intermediate 695-96-5 BrC6H3ClOH C6H4BrClO C6H4OBrCl Building Blocks Oxygen Compounds Organic Building Blocks Phenols Aromatic Phenols Phenol&Thiophenol&Mercaptan Bromine Compounds Chlorine Compounds Phenols Organic Building Blocks Oxygen Compounds 695-96-5