ethyl quinoline-2-carboxylate
- CAS No.
- 4491-33-2
- Chemical Name:
- ethyl quinoline-2-carboxylate
- Synonyms
- ethyl quinoline-2-carboxylate;Ethyl quinoline-2-carboxylic acid;2-Quinoline carbocylic acid ethyl ester;2-Quinolinecarboxylic acid, ethyl ester
- CBNumber:
- CB62500355
- Molecular Formula:
- C12H11NO2
- Molecular Weight:
- 201.22
- MDL Number:
- MFCD02149441
- MOL File:
- 4491-33-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethylquinoline-2-carboxylate | E932025 | 1g | $75 |
| Ethylquinoline-2-carboxylate | Y9139 | 1g | $93 |
| Ethylquinoline-2-carboxylate | Y9139 | 250mg | $74 |
| ETHYL QUINOLINE-2-CARBOXYLATE 95.00% | CHM0307665 | 5MG | $496.61 |
| Ethylquinoline-2-carboxylate 98% | A202390 | 250mg | $11 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
ethyl quinoline-2-carboxylate price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | E932025 | Ethylquinoline-2-carboxylate | 4491-33-2 | 1g | $75 | 2021-12-16 | Buy |
| AK Scientific | Y9139 | Ethylquinoline-2-carboxylate | 4491-33-2 | 1g | $93 | 2021-12-16 | Buy |
| AK Scientific | Y9139 | Ethylquinoline-2-carboxylate | 4491-33-2 | 250mg | $74 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0307665 | ETHYL QUINOLINE-2-CARBOXYLATE 95.00% | 4491-33-2 | 5MG | $496.61 | 2021-12-16 | Buy |
| Ambeed | A202390 | Ethylquinoline-2-carboxylate 98% | 4491-33-2 | 250mg | $11 | 2021-12-16 | Buy |
ethyl quinoline-2-carboxylate Chemical Properties,Uses,Production
Chemical Properties
yellow powder
Synthesis
93-10-7
75-03-6
4491-33-2
General procedure for the synthesis of ethyl 2-quinolinecarboxylate (6) from quinaldic acid (5) (2.0 g, 11.55 mmol) and ethyl iodide: quinaldic acid (5), dry K2CO3 (3.19 g, 23.10 mmol) and anhydrous DMF (24 mL) were mixed and stirred under argon protection until completely dissolved. Ethyl iodide (2.77 mL, 34.65 mmol) was then added and the reaction was stirred at 60 °C for 18 hours. After completion of the reaction, 30% cooled aqueous HCl solution (30 mL) was added for acidification. The reaction mixture was neutralized with saturated NaHCO3 solution until gas production stopped. The reaction mixture was extracted with ethyl acetate (3 x 60 mL). The organic phases were combined, washed with brine (30 mL), dried over anhydrous Na2SO4 and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with hexane/ethyl acetate (8:2) as eluent to give ethyl 2-quinolinecarboxylate (6) as a translucent oil in quantitative yield. the TLC Rf value was 0.51 (hexane/ethyl acetate 7:3). νmax/cm-1 by IR (pure): 3061, 2982, 2938, 2904, 1714, 1463. 1368, 1312, 1133, 1103, 1016, 844, 774.1H NMR (400MHz, CDCl3) δ 7.96-7.94 (m, 1H), 7.85-7.81 (m, 1H), 7.76-7.73 (m, 1H), 7.42-7.36 (m, 2H), 7.22-7.18 (m, 1H), 4.22-7.18 (m, 1H). 1H), 4.22-4.17 (m, 2H), 1.14-1.10 (m, 3H).13C NMR (100 MHz, CDCl3) δ 164.9, 147.9, 147.2, 136.8, 130.3, 129.8, 128.9, 128.1, 127.2, 120.6, 61.7, 14.1. HRMS (ESI+) calculated value C12H11NO2 [M+H]+ 202.0868, measured value 202.0868.
References
[1] Tetrahedron Letters, 2017, vol. 58, # 33, p. 3311 - 3315
ethyl quinoline-2-carboxylate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
ethyl quinoline-2-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3590 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9546 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30227 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Shandong Liteng Biotechnology Co. , Ltd. | +86-18663721413 +86-15552573001 | rosy@litengpharm.com | China | 3280 | 58 |
| Shanghai Likang New Materials Co., Limited | +86-16631818819 +86-17736933208 | 3684455296@qq.com | China | 9300 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 6085 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| BeiJing Hwrk Chemicals Limted | 0757-86329057 18934348241 | sales4.gd@hwrkchemical.com | China | 14063 | 55 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18729 | 57 |
View Lastest Price from ethyl quinoline-2-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-12 | Ethyl 2-quinolinecarboxylate
4491-33-2
|
US $1.00-0.00 / KG | 1KG | 99% | 20000KG | Shaanxi Dideu Medichem Co. Ltd |
-
- Ethyl 2-quinolinecarboxylate
4491-33-2
- US $1.00-0.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
4491-33-2(ethyl quinoline-2-carboxylate)Related Search:
1of3
