3-Amino-1,2-benzenediol
- CAS No.
- 20734-66-1
- Chemical Name:
- 3-Amino-1,2-benzenediol
- Synonyms
- 3-aMinobenzene-1,2-diol;3-Amino-1,2-benzenediol;1,2-Benzenediol, 3-aMino-;3-Amino benzene-1,2-diol / 3-Amino catechol hydrochloride
- CBNumber:
- CB62528751
- Molecular Formula:
- C6H7NO2
- Molecular Weight:
- 125.13
- MDL Number:
- MFCD14584779
- MOL File:
- 20734-66-1.mol
- MSDS File:
- SDS
| Melting point | 142-145 °C |
|---|---|
| Boiling point | 297.0±25.0 °C(Predicted) |
| Density | 1.412±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 1 mg/ml |
| form | A solid |
| pka | 9.59±0.10(Predicted) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2908190090 | |||||||||
| NFPA 704 |
|
3-Amino-1,2-benzenediol price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 36366 | 3-Aminocatechol ≥95% | 20734-66-1 | 5mg | $32 | 2026-04-30 | Buy |
| Cayman Chemical | 36366 | 3-Aminocatechol ≥95% | 20734-66-1 | 10mg | $61 | 2026-04-30 | Buy |
| Cayman Chemical | 36366 | 3-Aminocatechol ≥95% | 20734-66-1 | 50mg | $186 | 2026-04-30 | Buy |
| Cayman Chemical | 36366 | 3-Aminocatechol ≥95% | 20734-66-1 | 100mg | $341 | 2026-04-30 | Buy |
| ChemScene | CS-0030172 | 3-Aminobenzene-1,2-diol ≥98% | 20734-66-1 | 250mg | $296 | 2026-06-04 | Buy |
3-Amino-1,2-benzenediol Chemical Properties, Uses, Production
Uses
Degradation of Acid Black 1 reveals the formation of 3-Aminocatechol as one of the intermediates.
Synthesis
6299-67-8
20734-66-1
2,3-Dimethoxyaniline (438 μL, 3.26 mmol) was used as raw material and dissolved in dichloromethane (5.0 mL). A 1 mol/L solution of boron tribromide/dichloromethane (11.4 mL, 11.4 mmol) was slowly added dropwise at -78 °C under argon protection. After the dropwise addition, the reaction system was slowly warmed to room temperature and stirred overnight. Upon completion of the reaction, the reaction was quenched with saturated aqueous sodium bicarbonate solution and subsequently neutralized with saturated aqueous ammonium chloride solution. The reaction mixture was extracted with ethyl acetate and the organic phase was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate) to afford the target product 3-aminobenzene-1,2-diol (67 mg, 16% yield).
IC 50
MMP-2: 20 μM (IC50); MMP-8: 26 μM (IC50); MMP-9: 16 μM (IC50); MMP-14: 16.3 μM (IC50)
References
[1] Patent: JP2016/124812, 2016, A. Location in patent: Paragraph 0098
[2] Patent: US2003/65018, 2003, A1
[3] Patent: WO2007/71434, 2007, A1. Location in patent: Page/Page column 60-61
3-Amino-1,2-benzenediol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Nanjing JinruiJiuAn Biotechnology Co., Ltd. | 025-58196018 800028039 | sales@fartop.net | China | 2227 | 55 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9954 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4975 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
