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Methyl 4-fluoro-3-(trifluoroMethyl)benzoate

CAS No.
176694-36-3
Chemical Name:
Methyl 4-fluoro-3-(trifluoroMethyl)benzoate
Synonyms
Methyl 4-fluoro-3-(trifluoroMethyl)benzoate;4-Fluoro-3-trifluoromethylbenzoic acid methyl ester;Benzoic acid, 4-fluoro-3-(trifluoroMethyl)-, Methyl ester
CBNumber:
CB62550325
Molecular Formula:
C9H6F4O2
Molecular Weight:
222.14
MDL Number:
MFCD06203709
MOL File:
176694-36-3.mol
MSDS File:
SDS
Last updated:2026-05-28 03:30:26
Product description Number Pack Size Price
Methyl 4-fluoro-3-(trifluoromethyl)benzoate >98% PC201175 1g $21
Methyl 4-fluoro-3-(trifluoromethyl)benzoate >98% PC201175 5g $37
Methyl 4-fluoro-3-(trifluoromethyl)benzoate >98% PC201175 25g $176
Methyl 4-fluoro-3-(trifluoromethyl)benzoate >98% PC201175 100g $685
Methyl 4-fluoro-3-(trifluoromethyl)benzoate >98% PC201175 1g $21
More product size

Methyl 4-fluoro-3-(trifluoroMethyl)benzoate Properties

storage temp. Sealed in dry,Room Temperature
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code  2916399090

Methyl 4-fluoro-3-(trifluoroMethyl)benzoate price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC201175 Methyl 4-fluoro-3-(trifluoromethyl)benzoate >98% 176694-36-3 1g $21 2026-06-04 Buy
Apolloscientific PC201175 Methyl 4-fluoro-3-(trifluoromethyl)benzoate >98% 176694-36-3 5g $37 2026-06-04 Buy
Apolloscientific PC201175 Methyl 4-fluoro-3-(trifluoromethyl)benzoate >98% 176694-36-3 25g $176 2026-06-04 Buy
Apolloscientific PC201175 Methyl 4-fluoro-3-(trifluoromethyl)benzoate >98% 176694-36-3 100g $685 2026-06-04 Buy
Apolloscientific PC201175 Methyl 4-fluoro-3-(trifluoromethyl)benzoate >98% 176694-36-3 1g $21 2026-06-04 Buy
Product number Packaging Price Buy
PC201175 1g $21 Buy
PC201175 5g $37 Buy
PC201175 25g $176 Buy
PC201175 100g $685 Buy
PC201175 1g $21 Buy

Methyl 4-fluoro-3-(trifluoroMethyl)benzoate Chemical Properties,Uses,Production

Synthesis

Methanol

67-56-1

4-Fluoro-3-(trifluoromethyl)benzoic acid

67515-55-3

Methyl 4-fluoro-3-(trifluoroMethyl)benzoate

176694-36-3

Concentrated hydrochloric acid was slowly added to a stirred solution of 4-fluoro-3-(trifluoromethyl)benzoic acid (10.0 g, 48.1 mmol) in methanol (100 mL). Subsequently, sulfuric acid (4 mL, 73.4 mmol) was added dropwise at room temperature and the reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, 200 mL of aqueous sodium bicarbonate was added to neutralize the reaction mixture, which was then extracted with ethyl acetate (100 mL × 3). The organic phases were combined, washed with saturated saline (100 mL × 2), dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford the title compound methyl 4-fluoro-3-trifluoromethylbenzoate (9.4 g, 88% yield) as a light yellow oil.1H NMR (400 MHz, CDCl3) δ 8.33 (dd, J = 6.8, 1.6 Hz, 1H), 8.28- 8.22 (m, 1H), 7.28 (t, 1H), 3.95 (s, 3H).

References

[1] Patent: WO2014/206344, 2014, A1. Location in patent: Page/Page column 100
[2] Patent: WO2006/50830, 2006, A1. Location in patent: Page/Page column 47

Methyl 4-fluoro-3-(trifluoroMethyl)benzoate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 73)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
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Changzhou Ansciep Chemical Co., Ltd.
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Alchem Pharmtech,Inc.
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career henan chemical co
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Fuxin Pharmaceutical
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Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
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Changzhou Anxuan Chemical Co., Ltd
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Labnetwork lnc.
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View Lastest Price from Methyl 4-fluoro-3-(trifluoroMethyl)benzoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 4-fluoro-3-(trifluoroMethyl)benzoate pictures 2021-07-13 Methyl 4-fluoro-3-(trifluoroMethyl)benzoate
176694-36-3
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
Methyl 4-fluoro-3-(trifluoromethyl)benzoate pictures 2020-01-10 Methyl 4-fluoro-3-(trifluoromethyl)benzoate
176694-36-3
$1.00 1KG 99% 200kg Career Henan Chemical Co

Methyl 4-fluoro-3-(trifluoroMethyl)benzoate Spectrum

4-Fluoro-3-trifluoromethylbenzoic acid methyl ester Methyl 4-fluoro-3-(trifluoroMethyl)benzoate Benzoic acid, 4-fluoro-3-(trifluoroMethyl)-, Methyl ester 176694-36-3