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1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl-

1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl- structure

CAS No.: 183208-22-2

Chemical Name:: 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl-

Synonyms: 5-BroMo-1-Methyl-7-azaind..;5-BroMo-1-Methyl-7-azaindole;5-BroMo-1-Methylpyrrolo[2,3-b]pyridine;5-broMo-1-Methyl-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl-

CBNumber:: CB62570321

Molecular Formula:: C8H7BrN2

Molecular Weight:: 211.06

MDL Number:: MFCD14706089

MOL File:: 183208-22-2.mol

MSDS File:: SDS

Last updated:2026-05-28 03:54:36

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1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl- Properties

Boiling point	294.3±20.0 °C(Predicted)
Density	1.60±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	3.11±0.30(Predicted)
Appearance	Light brown to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P264-P270-P301+P312-P330-P501-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405

1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl- price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	IHA20822	5-Bromo-1-methyl-7-azaindole	183208-22-2	5g	$354	2026-06-04	Buy
Matrix Scientific	112974	5-Bromo-1-methyl-7-azaindole	183208-22-2	1.00g	$227	2026-05-18	Buy
Matrix Scientific	112974	5-Bromo-1-methyl-7-azaindole	183208-22-2	5.00g	$624	2026-05-18	Buy
Synthonix	B7982	5-Bromo-1-methyl-7-azaindole 97.0%	183208-22-2	100mg	$18	2026-05-06	Buy
Synthonix	B7982	5-Bromo-1-methyl-7-azaindole 97.0%	183208-22-2	250mg	$24	2026-05-06	Buy

Product number	Packaging	Price	Buy
IHA20822	5g	$354	Buy
112974	1.00g	$227	Buy
112974	5.00g	$624	Buy
B7982	100mg	$18	Buy
B7982	250mg	$24	Buy

1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl- Chemical Properties, Uses, Production

Synthesis

183208-35-7

74-88-4

1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl-

183208-22-2

Sodium hydride (NaH, 365 mg, 9.1 mmol) was slowly added to a solution of 5-bromo-7-azaindole (1.5 g, 7.6 mmol) in N,N-dimethylformamide (DMF, 10 mL) at 0 °C. The reaction mixture was stirred at room temperature for 1.5 hours. Subsequently, iodomethane (MeI, 1.4 g, 9.8 mmol) was added and stirring was continued overnight at room temperature. Upon completion of the reaction, the reaction was quenched with saturated aqueous sodium bicarbonate (NaHCO3) solution, followed by the addition of ammonium chloride (NH4Cl, 10 mL) solution. The mixture was separated between water (20 mL) and ethyl acetate (EA, 20 mL). The organic layer was washed sequentially with water (10 mL) and saturated brine (10 mL) and dried over anhydrous sodium sulfate (Na2SO4). The solvent was removed under reduced pressure to afford 5-bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine (1.7 g, yield: quantitative) as light yellow crystals.' HNMR (300 MHz, CDCl3): δ= 8.34 (d, J = 2.1 Hz, 1H), 8.01 (d, J = 2.4 Hz, 1H), 7.18 (d, J = 3.6 Hz, 1H), 6.39 (d, J = 3.3 Hz, 1H), 3.86 (s, 3H).

References

[1] Patent: WO2016/123392, 2016, A2. Location in patent: Paragraph 00786
[2] Patent: US2017/8889, 2017, A1. Location in patent: Paragraph 0149; 0150
[3] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 17, p. 5734 - 5739
[4] Beilstein Journal of Organic Chemistry, 2016, vol. 12, p. 309 - 313
[5] Marine Drugs, 2015, vol. 13, # 1, p. 460 - 492

1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl- Preparation Products And Raw materials

Raw materials

5-Bromo-7-azaindole Iodomethane Sodium hydride N,N-Dimethylformamide

Preparation Products

1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl- Suppliers

Global Suppliers ( 60)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Keepontech Co.,Ltd	021-54849683 13601642561	sales@keepontech.com	China	998	59
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	29977	65
Shanghai Devinchem Ltd	027-65318838 13646286950	sales@devinchem.com	China	2983	58
Shanghai JONLN Reagent Co., Ltd.	400-0066400 13621662912	422131432@qq.com	China	9970	55
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
ShangHai AmK Pharmaceutical Technology Co., Ltd.	微信 18019252918 18019252918	sale@amkchem.com	China	14982	55
SuZhou ShiYa Biopharmaceuticals, Inc.	0512-0512-52358471 17715136450	sales@shiyabiopharm.com	China	9814	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
ChengDu TongChuangYuan Pharmaceutical Co.Ltd	028-83379370 13880556291	tcy@tcypharm.com	China	8696	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58

Supplier	Advantage
Shanghai Keepontech Co.,Ltd	59
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65
Shanghai Devinchem Ltd	58
Shanghai JONLN Reagent Co., Ltd.	55
Bide Pharmatech Ltd.	60
ShangHai AmK Pharmaceutical Technology Co., Ltd.	55
SuZhou ShiYa Biopharmaceuticals, Inc.	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
ChengDu TongChuangYuan Pharmaceutical Co.Ltd	58
Amadis Chemical Company Limited	58

1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl- Spectrum

5-BroMo-1-Methyl-7-azaind...(183208-22-2)¹HNMR

183208-22-2 (1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl-) Related Search:

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1H-Pyrrolo[2,3-b]pyridine, 5-broMo-1-ethenyl-

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5-BroMo-1-Methyl-7-azaindole 5-broMo-1-Methyl-1H-pyrrolo[2,3-b]pyridine 5-BroMo-1-Methylpyrrolo[2,3-b]pyridine 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-methyl- 5-BroMo-1-Methyl-7-azaind.. 183208-22-2