ChemicalBook >> CAS DataBase List >>1-(3-Methoxypropyl)-4-piperidinamine
1-(3-Methoxypropyl)-4-piperidinamine
- CAS No.
- 179474-79-4
- Chemical Name:
- 1-(3-Methoxypropyl)-4-piperidinamine
- Synonyms
- Prucalopride intermediateB;4-AMino-1-(3-Methoxypropy...;3-methoxy propyl piperidinamine;Prucalopride Succinate iMpuritO;1-(3-methoxypropyl) -4-piperidine;1-(3-Methoxypropyl)-4-piperidimine;1-(3-Methoxypropyl)piperidin-4-aMine;1-(3-Methoxypropyl)-4-piperidinamine;Prucalopride Succinate interMediate B;4-AMino-1-(3-Methoxypropyl)piperidine
- CBNumber:
- CB62589756
- Molecular Formula:
- C9H20N2O
- Molecular Weight:
- 172.27
- MDL Number:
- MFCD11104531
- MOL File:
- 179474-79-4.mol
- MSDS File:
- SDS
Last updated:2025-07-24 18:11:59
| Product description | Number | Pack Size | Price |
| 1-(3-methoxypropyl)piperidin-4-amine | Y1133 | 1g | $95 |
| 1-(3-methoxypropyl)piperidin-4-amine | Y1133 | 10g | $236 |
| 4-Amino-1-(3-methoxypropyl)piperidine 95+% | 115680 | 1g | $572 |
| 4-Amino-1-(3-methoxypropyl)piperidine 95+% | 115680 | 5g | $1580 |
| 4-Amino-1-(3-methoxypropyl)piperidine 95+% | 115680 | 10g | $2222 |
| More product size | |||
| Boiling point | 249℃ |
|---|---|
| Density | 0.946 |
| Flash point | 105℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 10.49±0.20(Predicted) |
| form | Oil |
| color | Colourless to Pale Yellow |
| InChI | InChI=1S/C9H20N2O/c1-12-8-2-5-11-6-3-9(10)4-7-11/h9H,2-8,10H2,1H3 |
| InChIKey | HIXAJGFVNMKLML-UHFFFAOYSA-N |
| SMILES | N1(CCCOC)CCC(N)CC1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
1-(3-Methoxypropyl)-4-piperidinamine price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | Y1133 | 1-(3-methoxypropyl)piperidin-4-amine | 179474-79-4 | 1g | $95 | 2021-12-16 | Buy |
| AK Scientific | Y1133 | 1-(3-methoxypropyl)piperidin-4-amine | 179474-79-4 | 10g | $236 | 2021-12-16 | Buy |
| Matrix Scientific | 115680 | 4-Amino-1-(3-methoxypropyl)piperidine 95+% | 179474-79-4 | 1g | $572 | 2021-12-16 | Buy |
| Matrix Scientific | 115680 | 4-Amino-1-(3-methoxypropyl)piperidine 95+% | 179474-79-4 | 5g | $1580 | 2021-12-16 | Buy |
| Matrix Scientific | 115680 | 4-Amino-1-(3-methoxypropyl)piperidine 95+% | 179474-79-4 | 10g | $2222 | 2021-12-16 | Buy |
1-(3-Methoxypropyl)-4-piperidinamine Chemical Properties,Uses,Production
Uses
1-(3-Methoxypropyl)-4-piperidinamine is a useful synthetic intermediate in the synthesis of Prucalopride Succinate (P838950); a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
Synthesis
N-(1-(3-methoxypropyl)piperidin-4-yl)acetamide (10.72g, 0.05mol) was added to HCl-methanol solution (0.5M, 180ml), and the temperature was controlled at 2025°C After the reaction was detected, it was filtered, and the filter cake was washed with dichloromethane and dried to obtain 1-(3-Methoxypropyl)-4-piperidinamine with a yield of 96.4% and a purity of 99.7%.
References
[1] Patent: CN106146386, 2016, A. Location in patent: Paragraph 0064; 0065; 0066; 0067
1-(3-Methoxypropyl)-4-piperidinamine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 173)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Innopharm Industrial Co., Ltd. | +86-21-59960785 +86-17701845089 | sales@hoyaopharm.com | China | 338 | 58 |
| Hefei TianRui Pharmaceutical Chemical Co., Ltd. | +86-0551-68665055 +86-+86-18616906106 | sales@trywchem.com | China | 187 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 4000 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +8617392709771 | 1097@dideu.com | China | 3996 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21591 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29820 | 58 |
View Lastest Price from 1-(3-Methoxypropyl)-4-piperidinamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | 1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
|
US $0.00-0.00 / KG | 1KG | 99.0% | 1000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-09-25 | 1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
|
US $6.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2025-04-29 | 1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
|
US $1.00 / KG | 1KG | 99% | 1T | Shaanxi Dideu Medichem Co. Ltd |
-
- 1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
- US $6.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 1-(3-Methoxypropyl)-4-piperidinamine
179474-79-4
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
1-(3-Methoxypropyl)-4-piperidinamine
4-AMino-1-(3-Methoxypropyl)piperidine
4-AMino-1-(3-Methoxypropy...
4-PiperidinaMine, 1-(3-Methoxypropyl)-
1-(3-Methoxypropyl)piperidin-4-aMine
Prucalopride Succinate interMediate B
Prucalopride intermediateB
1-(3-Methoxypropyl)-4-piperidimine
1-(3-Methoxypropyl)-4-piperidinamine (Plucabili impurity)
Prucalopride Succinate iMpuritO
3-methoxy propyl piperidinamine
1-(3-methoxypropyl) -4-piperidine
1- (3-methoxypropyl) -4-piperidine amine
179474-79-4
179474-97-4
