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JNJ-28312141

CAS No.
885692-52-4
Chemical Name:
JNJ-28312141
Synonyms
CS-2012;JNJ-28312141;JNJ-28312141(JNJ-141);JNJ 28312141; JNJ28312141;JNJ-28312141; JNJ28312141; JNJ 28312141.;4-Cyano-N-(5-(1-(2-(dimethylamino)acetyl)piperidin-4-yl)-2',3',4',5'-tetrahydro-[1,1'-biphenyl;4-CYANO-N-[2-(CYCLOHEX-1-EN-1-YL)-4-{1-[2-(DIMETHYLAMINO)ACETYL]PIPERIDIN-4-YL}PHENYL]-1H-IMIDAZOLE-2-CARBOXAMIDE;1H-Imidazole-2-carboxamide, 5-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[2-(dimethylamino)acetyl]-4-piperidinyl]phenyl]-
CBNumber:
CB62621140
Molecular Formula:
C26H32N6O2
Molecular Weight:
460.57
MDL Number:
MFCD22631505
MOL File:
885692-52-4.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
JNJ-28312141 KKB69252 10mg $986.4
JNJ-28312141 KKB69252 25mg $1608.25
JNJ-28312141 KKB69252 50mg $2572.5
JNJ-28312141 CS-0007079 1mg $379
JNJ-28312141 CS-0007079 5mg $948

JNJ-28312141 Properties

Density 1.27±0.1 g/cm3(Predicted)
pka 7.30±0.10(Predicted)
form White powder.
FDA UNII YKQ241VJ92

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

JNJ-28312141 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth KKB69252 JNJ-28312141 885692-52-4 10mg $986.4 2026-06-04 Buy
Biosynth KKB69252 JNJ-28312141 885692-52-4 25mg $1608.25 2026-06-04 Buy
Biosynth KKB69252 JNJ-28312141 885692-52-4 50mg $2572.5 2026-06-04 Buy
ChemScene CS-0007079 JNJ-28312141 885692-52-4 1mg $379 2026-06-04 Buy
ChemScene CS-0007079 JNJ-28312141 885692-52-4 5mg $948 2026-06-04 Buy
Product number Packaging Price Buy
KKB69252 10mg $986.4 Buy
KKB69252 25mg $1608.25 Buy
KKB69252 50mg $2572.5 Buy
CS-0007079 1mg $379 Buy
CS-0007079 5mg $948 Buy

JNJ-28312141 Chemical Properties,Uses,Production

Uses

JNJ-28312141 is an inhibitor for colony-stimulating factor-1 receptor (CSF-1R or FMS), with an IC50 of 0.69 nM. JNJ-28312141 inhibits proliferation of BDBM, MV-4-11, M-o7e, TF-1 with an IC50s of 2.6, 21, 41 and 150 nM, respectively. JNJ-28312141 exhibits anti-inflammatory activity in mouse arthritis model[1].

References

[1] Illig CR, et al., Optimization of a potent class of arylamide colony-stimulating factor-1 receptor inhibitors leading to anti-inflammatory clinical candidate 4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141). J Med Chem. 2011 Nov 24;54(22):7860-83. DOI:10.1021/jm200900q

JNJ-28312141 Preparation Products And Raw materials

Raw materials

Preparation Products

JNJ-28312141 Suppliers

Global( 45)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc.
13564774135 marketing@targetmol.com United States 19950 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131885 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai XingMo Biotechnology Co., Ltd. +86 13524779951; 13524779951 2075692521@qq.com China 294 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4565 58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd. 13611835272 13611835272 mmwang@sunwaypharm.com China 44090 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 024-88590548 18698872706 757984502@qq.com China 960 58

View Lastest Price from JNJ-28312141 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
JNJ-28312141 pictures 2026-07-27 JNJ-28312141
885692-52-4
$1520.00-2500.00 10g TargetMol Chemicals Inc.
  • JNJ-28312141 pictures
  • JNJ-28312141
    885692-52-4
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.
CS-2012 JNJ-28312141; JNJ28312141; JNJ 28312141. JNJ 28312141; JNJ28312141 JNJ-28312141 JNJ-28312141(JNJ-141) 4-Cyano-N-(5-(1-(2-(dimethylamino)acetyl)piperidin-4-yl)-2',3',4',5'-tetrahydro-[1,1'-biphenyl 4-CYANO-N-[2-(CYCLOHEX-1-EN-1-YL)-4-{1-[2-(DIMETHYLAMINO)ACETYL]PIPERIDIN-4-YL}PHENYL]-1H-IMIDAZOLE-2-CARBOXAMIDE 1H-Imidazole-2-carboxamide, 5-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[2-(dimethylamino)acetyl]-4-piperidinyl]phenyl]- 885692-52-4 C26H32N6O2