JNJ-28312141
- CAS No.
- 885692-52-4
- Chemical Name:
- JNJ-28312141
- Synonyms
- CS-2012;JNJ-28312141;JNJ-28312141(JNJ-141);JNJ 28312141; JNJ28312141;JNJ-28312141; JNJ28312141; JNJ 28312141.;4-Cyano-N-(5-(1-(2-(dimethylamino)acetyl)piperidin-4-yl)-2',3',4',5'-tetrahydro-[1,1'-biphenyl;4-CYANO-N-[2-(CYCLOHEX-1-EN-1-YL)-4-{1-[2-(DIMETHYLAMINO)ACETYL]PIPERIDIN-4-YL}PHENYL]-1H-IMIDAZOLE-2-CARBOXAMIDE;1H-Imidazole-2-carboxamide, 5-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[2-(dimethylamino)acetyl]-4-piperidinyl]phenyl]-
- CBNumber:
- CB62621140
- Molecular Formula:
- C26H32N6O2
- Molecular Weight:
- 460.57
- MDL Number:
- MFCD22631505
- MOL File:
- 885692-52-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| JNJ-28312141 | KKB69252 | 10mg | $986.4 |
| JNJ-28312141 | KKB69252 | 25mg | $1608.25 |
| JNJ-28312141 | KKB69252 | 50mg | $2572.5 |
| JNJ-28312141 | CS-0007079 | 1mg | $379 |
| JNJ-28312141 | CS-0007079 | 5mg | $948 |
| Density | 1.27±0.1 g/cm3(Predicted) |
|---|---|
| pka | 7.30±0.10(Predicted) |
| form | White powder. |
| FDA UNII | YKQ241VJ92 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
JNJ-28312141 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | KKB69252 | JNJ-28312141 | 885692-52-4 | 10mg | $986.4 | 2026-06-04 | Buy |
| Biosynth | KKB69252 | JNJ-28312141 | 885692-52-4 | 25mg | $1608.25 | 2026-06-04 | Buy |
| Biosynth | KKB69252 | JNJ-28312141 | 885692-52-4 | 50mg | $2572.5 | 2026-06-04 | Buy |
| ChemScene | CS-0007079 | JNJ-28312141 | 885692-52-4 | 1mg | $379 | 2026-06-04 | Buy |
| ChemScene | CS-0007079 | JNJ-28312141 | 885692-52-4 | 5mg | $948 | 2026-06-04 | Buy |
JNJ-28312141 Chemical Properties,Uses,Production
Uses
JNJ-28312141 is an inhibitor for colony-stimulating factor-1 receptor (CSF-1R or FMS), with an IC50 of 0.69 nM. JNJ-28312141 inhibits proliferation of BDBM, MV-4-11, M-o7e, TF-1 with an IC50s of 2.6, 21, 41 and 150 nM, respectively. JNJ-28312141 exhibits anti-inflammatory activity in mouse arthritis model[1].
References
[1] Illig CR, et al., Optimization of a potent class of arylamide colony-stimulating factor-1 receptor inhibitors leading to anti-inflammatory clinical candidate 4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141). J Med Chem. 2011 Nov 24;54(22):7860-83. DOI:10.1021/jm200900q
JNJ-28312141 Preparation Products And Raw materials
Raw materials
Preparation Products
JNJ-28312141 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai XingMo Biotechnology Co., Ltd. | +86 13524779951; 13524779951 | 2075692521@qq.com | China | 294 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 4565 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 13611835272 13611835272 | mmwang@sunwaypharm.com | China | 44090 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | 024-88590548 18698872706 | 757984502@qq.com | China | 960 | 58 |
View Lastest Price from JNJ-28312141 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-27 | JNJ-28312141
885692-52-4
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
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- JNJ-28312141
885692-52-4
- $1520.00-2500.00
- TargetMol Chemicals Inc.





