2-(TRIFLUOROACETYL)CYCLOHEXANONE
- CAS No.
- 387-89-3
- Chemical Name:
- 2-(TRIFLUOROACETYL)CYCLOHEXANONE
- Synonyms
- AKOS B029513;2-(TRIFLUOROACETYL)CYCLOHEXANONE;2-(trifluoroacetyl)cyclohexan-1-one;2-(2,2,2-trifluoroacetyl)cyclohexanone;Cyclohexanone, 2-(2,2,2-trifluoroacetyl)-;2-(2,2,2-trifluoroethanoyl)cyclohexan-1-one
- CBNumber:
- CB6266196
- Molecular Formula:
- C8H9F3O2
- Molecular Weight:
- 194.15
- MDL Number:
- MFCD07779548
- MOL File:
- 387-89-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2914790090 |
2-(TRIFLUOROACETYL)CYCLOHEXANONE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | T793713 | 2-(2,2,2-Trifluoroacetyl)cyclohexanone | 387-89-3 | 50mg | $45 | 2021-12-16 | Buy |
| Apolloscientific | PC904873 | 2-(Trifluoroacetyl)cyclohexanone | 387-89-3 | 5g | $93 | 2021-12-16 | Buy |
| AK Scientific | W5936 | 2-(Trifluoroacetyl)cyclohexanone | 387-89-3 | 100mg | $227 | 2021-12-16 | Buy |
| Matrix Scientific | 090506 | 2-(2,2,2-Trifluoroacetyl)cyclohexanone 95+% | 387-89-3 | 250mg | $227 | 2021-12-16 | Buy |
| AK Scientific | W5936 | 2-(Trifluoroacetyl)cyclohexanone | 387-89-3 | 2.5g | $368 | 2021-12-16 | Buy |
2-(TRIFLUOROACETYL)CYCLOHEXANONE Chemical Properties,Uses,Production
Uses
2-(2,2,2-Trifluoroacetyl)cyclohexanone is a useful reactant for the synthesis of fluorinated 1-?desazapurines.
Synthesis
383-63-1
108-94-1
387-89-3
GENERAL PROCEDURE: In a dry Schlenk tube, NaH (6.0 mmol) was stirred with ethyl trifluoroacetate (6.0 mmol) in THF (5 mL) for 10 minutes at room temperature under argon protection. Subsequently, a THF (5 mL) solution of cyclohexanone (5.0 mmol) was added dropwise to the above mixture at 0 °C and under argon protection. The reaction mixture was stirred at the set temperature for 2-6 h. After that, it was cooled to 0 °C again and the reaction was quenched with 6 mL of 1 mol/L HCl solution. After continued stirring for 15 min, the reaction mixture was neutralized with saturated NaHCO3 solution. After conventional post-treatment, the residue was purified by silica gel column chromatography to afford the target product 2-(trifluoroacetyl)cyclohexanone.
References
[1] Tetrahedron, 2014, vol. 70, # 31, p. 4668 - 4674
[2] Magnetic Resonance in Chemistry, 1993, vol. 31, # 4, p. 323 - 328
[3] Journal of the American Chemical Society, 1953, vol. 75, p. 4753
[4] New Journal of Chemistry, 2007, vol. 31, # 6, p. 936 - 946
[5] RSC Advances, 2016, vol. 6, # 46, p. 40277 - 40286
2-(TRIFLUOROACETYL)CYCLOHEXANONE Preparation Products And Raw materials
2-(TRIFLUOROACETYL)CYCLOHEXANONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 12932 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20342 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 | alfa10@alfachem.cn | China | 12932 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20191 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
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