3-ACETYL-5-BROMOPYRIDINE
- CAS No.
- 38940-62-4
- Chemical Name:
- 3-ACETYL-5-BROMOPYRIDINE
- Synonyms
- 5-Acetyl-3-bromopyridine;3-BROMO-5-ACETYLPYRIDINE;3-ACETYL-5-BROMOPYRIDINE;5-Bromo-3-acetylpyridine;3-Acetyl-5-bromopyridine,97%;3-Acetyl-5-bromopyridine >1-(5-Bromo-3-pyridyl)ethanone;1-(5-bromo-3-pyridinyl)ethanone;1-(5-BROMOPYRIDIN-3-YL)ETHANONE;Ethanone, 1-(5-bromo-3-pyridinyl)-
- CBNumber:
- CB6272959
- Molecular Formula:
- C7H6BrNO
- Molecular Weight:
- 200.03
- MDL Number:
- MFCD03086033
- MOL File:
- 38940-62-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Acetyl-5-bromopyridine 97% | 703893 | 5g | $184 |
| 3-Acetyl-5-bromopyridine 97% | 703893 | 1g | $157 |
| 3-Acetyl-5-bromopyridine >97.0%(GC) | A2376 | 1g | $56 |
| 3-Acetyl-5-bromopyridine >97.0%(GC) | A2376 | 5g | $171 |
| 3-Acetyl-5-bromopyridine | A168510 | 1g | $50 |
| More product size | |||
| Melting point | 77-79°C |
|---|---|
| Boiling point | 279.3±25.0 °C(Predicted) |
| Density | 1.534±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Methanol |
| pka | 1.08±0.20(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
| BRN | 112808 |
| InChI | 1S/C7H6BrNO/c1-5(10)6-2-7(8)4-9-3-6/h2-4H,1H3 |
| InChIKey | LDBPZEQZCOUYFT-UHFFFAOYSA-N |
| SMILES | CC(=O)c1cncc(Br)c1 |
| CAS DataBase Reference | 38940-62-4(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39-36/37-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3-ACETYL-5-BROMOPYRIDINE price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 703893 | 3-Acetyl-5-bromopyridine 97% | 38940-62-4 | 5g | $184 | 2023-06-20 | Buy |
| Sigma-Aldrich | 703893 | 3-Acetyl-5-bromopyridine 97% | 38940-62-4 | 1g | $157 | 2022-05-15 | Buy |
| TCI Chemical | A2376 | 3-Acetyl-5-bromopyridine >97.0%(GC) | 38940-62-4 | 1g | $56 | 2026-03-19 | Buy |
| TCI Chemical | A2376 | 3-Acetyl-5-bromopyridine >97.0%(GC) | 38940-62-4 | 5g | $171 | 2026-03-19 | Buy |
| TRC | A168510 | 3-Acetyl-5-bromopyridine | 38940-62-4 | 1g | $50 | 2021-12-16 | Buy |
3-ACETYL-5-BROMOPYRIDINE Chemical Properties,Uses,Production
Chemical Properties
Hoar or pale yellow solid
Uses
3-Acetyl-5-bromopyridine is used in the synthesis of benzimidazole CYP11B2 inhibitors. Potent and selective aldosterone inhibitors are used to treat diseases such as those resulting in the stiffening of the heart.
Synthesis
75-16-1
183608-47-1
38940-62-4
To a solution of 5-bromo-N-methoxy-N-methylnicotinamide (2.08 g, 8.5 mmol) in tetrahydrofuran (THF, 20 mL) was slowly added methylmagnesium bromide (MeMgBr, 1.52 g, 12.75 mmol) at -78 °C. The reaction mixture was stirred at room temperature for 2 h before the reaction was quenched with deionized water. Subsequently, the reaction mixture was extracted with ethyl acetate (EtOAc) and the organic layer was washed with saturated brine and dried over anhydrous sodium sulfate (Na2SO4). After filtration, the filtrate was concentrated under reduced pressure and the resulting residue was purified by fast column chromatography to afford the target product 3-acetyl-5-bromopyridine (1.5 g, 88% yield).
References
[1] Patent: US2013/72679, 2013, A1. Location in patent: Paragraph 0893; 0894
[2] Patent: WO2013/37779, 2013, A1. Location in patent: Page/Page column 235; 236
3-ACETYL-5-BROMOPYRIDINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29820 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
View Lastest Price from 3-ACETYL-5-BROMOPYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 3-ACETYL-5-BROMOPYRIDINE
38940-62-4
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
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2021-07-02 | 3-ACETYL-5-BROMOPYRIDINE
38940-62-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
![]() |
2020-01-13 | 3-ACETYL-5-BROMOPYRIDINE
38940-62-4
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-

- 3-ACETYL-5-BROMOPYRIDINE
38940-62-4
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-

- 3-ACETYL-5-BROMOPYRIDINE
38940-62-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-

- 3-ACETYL-5-BROMOPYRIDINE
38940-62-4
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co
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