2-Methyl-indan-2-ylamine hydrochloride
- CAS No.
- 91817-66-2
- Chemical Name:
- 2-Methyl-indan-2-ylamine hydrochloride
- Synonyms
- 2-Methyl-indan-2-ylamine hydrochloride;2-Methyl-2,3-dihydro-1H-inden-2-amine hydrochloride
- CBNumber:
- CB62746241
- Molecular Formula:
- C10H14ClN
- Molecular Weight:
- 183.67786
- MDL Number:
- MFCD18432518
- MOL File:
- 91817-66-2.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-Methyl-indan-2-ylamine hydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | RDA81766 | 2-Methyl-2,3-dihydro-1H-inden-2-amine hydrochloride | 91817-66-2 | 100mg | $304 | 2026-06-05 | Buy |
| Biosynth | RDA81766 | 2-Methyl-2,3-dihydro-1H-inden-2-amine hydrochloride | 91817-66-2 | 1g | $767 | 2026-06-05 | Buy |
| Activate Scientific | AS121517-B | 2-Amino-2-methylindan HCl 98% | 91817-66-2 | 1g | $370 | 2026-06-04 | Buy |
| Matrix Scientific | 312485 | 2-Methyl-2,3-dihydro-1H-inden-2-amine hydrochloride | 91817-66-2 | 100.00mg | $115 | 2026-05-19 | Buy |
| Matrix Scientific | 312485 | 2-Methyl-2,3-dihydro-1H-inden-2-amine hydrochloride | 91817-66-2 | 250.00mg | $171 | 2026-05-19 | Buy |
2-Methyl-indan-2-ylamine hydrochloride Chemical Properties, Uses, Production
Synthesis
91142-58-4
91817-66-2
2-Methyl-2,3-dihydro-1H-indene-2-carboxylic acid (1.63 g, 9.26 mmol) was dissolved in acetone (15 mL), stirred and cooled to 0°C. To this cooled solution was sequentially added triethylamine (1.47 mL, 10.46 mmol) and ethyl chloroformate (1.00 mL, 10.46 mmol). The reaction mixture was stirred continuously at 0 °C for 40 min. Subsequently, a solution of sodium azide (903 mg, 13.89 mmol) in water (5 mL) was added slowly and dropwise over 1 min and stirring was continued for 1 h at 0°C. Upon completion of the reaction, the cooled suspension was partitioned between ethyl acetate and saturated brine, and the aqueous layer was extracted with additional ethyl acetate. The organic layers were combined and dried with anhydrous magnesium sulfate, followed by evaporation of the solvent to give an oily intermediate. This oily substance was dissolved in toluene (10 mL), heated to 100 °C and maintained for 20 min until nitrogen stopped escaping. After removing the solvent, the residue was dissolved in 5 M hydrochloric acid (20 mL) and heated to reflux overnight. After cooling, the reaction mixture was diluted with water and the insoluble material was extracted with ethyl acetate. The organic layer was again dried with anhydrous magnesium sulfate and evaporated to recover unreacted material (550 mg, 34%). The aqueous phase was evaporated to dryness under reduced pressure to afford the target product 2-methyl-2,3-dihydro-1H-inden-2-amine hydrochloride as a white powder (870 mg, 51%). The product was characterized by 1H-NMR (400 MHz, DMSO-d6): δ 8.42 (3H, broad single peak), 7.26 (2H, multiple peaks overlapping), 7.19 (2H, multiple peaks overlapping), 3.20 (2H, double peaks, J = 16.4 Hz), 2.99 (2H, double peaks, J = 16.4 Hz), 1.44 (3H, single peaks).
References
[1] Patent: WO2010/57865, 2010, A1. Location in patent: Page/Page column 25-26
[2] Patent: US2011/124559, 2011, A1
2-Methyl-indan-2-ylamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methyl-indan-2-ylamine hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JW & Y Pharmlab Co., Ltd. | 021-64340559 | xinyu_shi@jwypharmlab.com.cn | China | 11999 | 58 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Shanghai zhigan biotechnology co., LTD | zhiqianbio@126.com | China | 19765 | 58 | |
| Zhengzhou Alpha Chemical Co. LTD | 0371-53732842 13383863444 | 3838551451@qq.com | China | 9996 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +86-15658003402 | sales@newcanbio.com | China | 2087 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Bide Pharmatech Ltd. | 400-6005915 | sales@picasso-e.com | China | 39662 | 58 |
| Shanghai Yingxin laboratory equipment Co., Ltd | 021-021-59178156 15300768757 | 359382369@qq.com | China | 10667 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 17801761073 | Gsiyu@solarbio.com | China | 50460 | 58 |
| Beijing Famozi Pharmaceutical Technology Co., Ltd | 15811073878 | 2559355526@qq.com | China | 9996 | 58 |
