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Benzofuran-2-carboxylic acid

Benzofuran-2-carboxylic acid structure

CAS No.: 496-41-3

Chemical Name:: Benzofuran-2-carboxylic acid

Synonyms: AKOS 91692;AURORA 2460;AKOS AUF2077;COUMARILIC ACID;Compound Fr13623;RARECHEM AL BE 0556;TIMTEC-BB SBB000137;2-Carboxybenzofuran;OTAVA-BB BB0125160292;COUMARONE-2-CARBOXYLIC ACID

CBNumber:: CB6278401

Molecular Formula:: C9H6O3

Molecular Weight:: 162.14

MDL Number:: MFCD00005848

MOL File:: 496-41-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-22 18:57:36

Product description	Number	Pack Size	Price
Benzofuran-2-carboxylic acid 99%	307270	5g	$77.2
Benzofuran-2-carboxylic Acid >99.0%(GC)(T)	B1981	1g	$21
Benzofuran-2-carboxylic Acid >99.0%(GC)(T)	B1981	5g	$66
Benzofuran-2-carboxylic acid	B207743	500mg	$65
Benzofuran-2-carboxylic acid	B207743	100mg	$45
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Benzofuran-2-carboxylic acid Properties

Melting point	193-196 °C (lit.)
Boiling point	310-315°C
Density	1.2599 (rough estimate)
refractive index	1.5380 (estimate)
Flash point	310-315°C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol,Ethanol,Acetone
pka	3.12±0.30(Predicted)
form	Crystals or Powder
color	White to yellow
Water Solubility	partially soluble
Merck	14,2561
BRN	124204
InChI	1S/C9H6O3/c10-9(11)8-5-6-3-1-2-4-7(6)12-8/h1-5H,(H,10,11)
InChIKey	OFFSPAZVIVZPHU-UHFFFAOYSA-N
SMILES	OC(=O)c1cc2ccccc2o1
LogP	2.410
CAS DataBase Reference	496-41-3(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	7Z6NMG947L
NIST Chemistry Reference	Benzofuran-2-carboxylic acid(496-41-3)
EPA Substance Registry System	2-Benzofurancarboxylic acid (496-41-3)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-37/39

WGK Germany

RTECS

DF6490000

TSCA

TSCA listed

HazardClass

IRRITANT

HS Code

29329985

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Toxicity

mouse,LD50,intravenous,320mg/kg (320mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02495,

NFPA 704

	0
2		0

Benzofuran-2-carboxylic acid price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	307270	Benzofuran-2-carboxylic acid 99%	496-41-3	5g	$77.2	2026-03-19	Buy
TCI Chemical	B1981	Benzofuran-2-carboxylic Acid >99.0%(GC)(T)	496-41-3	1g	$21	2026-03-19	Buy
TCI Chemical	B1981	Benzofuran-2-carboxylic Acid >99.0%(GC)(T)	496-41-3	5g	$66	2026-03-19	Buy
TRC	B207743	Benzofuran-2-carboxylic acid	496-41-3	500mg	$65	2021-12-16	Buy
TRC	B207743	Benzofuran-2-carboxylic acid	496-41-3	100mg	$45	2021-12-16	Buy

Product number	Packaging	Price	Buy
307270	5g	$77.2	Buy
B1981	1g	$21	Buy
B1981	5g	$66	Buy
B207743	500mg	$65	Buy
B207743	100mg	$45	Buy

Benzofuran-2-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

Benzofuran-2-carboxylic acid was used in the synthesis of the oxymethyl-modified coumarinic acid-based cyclic DADLE (H-Tyr-D-Ala-Gly-Phe-D-Leu-OH) prodrug.

Synthesis Reference(s)

Journal of the American Chemical Society, 73, p. 872, 1951 DOI: 10.1021/ja01146a532
Organic Syntheses, Coll. Vol. 3, p. 209, 1955

Purification Methods

The acid crystallises from water. [Beilstein 18/6 V 419.]

Benzofuran-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Ethanol Potassium hydroxide Potassium carbonate 2-Butanone 3-Hydroxybenzaldehyde

Diethyl ether Benzene DIETHYL BROMOMALONATE Sulfuric acid 3-HYDROXYCOUMARIN

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Preparation Products

2,3-Dihydro-1-benzofuran-2-carboxylic acid N-(2-Bromophenyl)benzofuran-2-carboxamide N-(Benzofuran-2-yl)-4-chlorobenzaMide

Benzofuran-2-carboxylic acid Suppliers

Global( 268)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-18192627656	1059@dideu.com	China	3590	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	9546	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10236	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
ATK CHEMICAL COMPANY LIMITED	60
Jinan Carbotang Biotech Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Zhengzhou Alfa Chemical Co.,Ltd	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58

View Lastest Price from Benzofuran-2-carboxylic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-22	Benzofuran-2-carboxylic acid 496-41-3	US $31.00-76.00 / mg		99.84%	10g	TargetMol Chemicals Inc.
2026-04-22	Benzofuran-2-carboxylic acid 496-41-3	US $31.00-76.00 / mg		99.84%	10g	TargetMol Chemicals Inc.
2026-04-17	Benzofuran-2-carboxylic acid 496-41-3	US $2.00-5.00 / KG	0.1KG	99%	g-kg-tons	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Benzofuran-2-carboxylic acid
496-41-3
US $31.00-76.00 / mg
99.84%
TargetMol Chemicals Inc.

Benzofuran-2-carboxylic acid
496-41-3
US $31.00-76.00 / mg
99.84%
TargetMol Chemicals Inc.

Benzofuran-2-carboxylic acid
496-41-3
US $2.00-5.00 / KG
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Benzofuran-2-carboxylic acid Spectrum

Benzofuran-2-carboxylic acid(496-41-3)MS Benzofuran-2-carboxylic acid(496-41-3)¹HNMR Benzofuran-2-carboxylic acid(496-41-3)¹³CNMR Benzofuran-2-carboxylic acid(496-41-3)IR1 Benzofuran-2-carboxylic acid(496-41-3)IR2 Benzofuran-2-carboxylic acid(496-41-3)Raman

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4,5-BENZOFURAN-2-CARBOXYLIC ACID COUMARILIC ACID COUMARONE-2-CARBOXYLIC ACID BENZOFURAN-2-CARBOXYLIC ACID BENZO[B]FURAN-2-CARBOXYLIC ACID AURORA 2460 RARECHEM AL BE 0556 OTAVA-BB BB0125160292 TIMTEC-BB SBB000137 AKOS AUF2077 AKOS 91692 2,3-BENZOFURAN-2-CARBOXYLIC ACID 2-BENZOFURANCARBOXYLIC ACID 1-BENZOFURAN-2-CARBOXYLIC ACID 2-Carboxybenzofuran benzfuran-2-Carboxylic acid 2,3-Benzofuran-2-carboxylic acid, 98+% Benzofuran-2-carboxylicacid=Coumarilicacid Benzofuran-2-carboxylic acid 97% Benzo[b]furan-2-carboxylic acid, HPLC 98% Benzo[b]furan-2-carboxylic acid, 98+% Benzobüfuran-2-carboxylic acid, 98+% Coumarilic acid, Coumarone-2-carboxylic acid Benzofuran-2-carboxylic acid ,99% 2-Benzofurancarboxylicacid,99% Benzo[b]furan-2-carboxylic acid 97% Coumarilic acid, 1-Benzofuran-2-carboxylic acid benxofuran-2-carboxylic acid Benzofuran-2-carboxylic Acid > benzofurane-2-carboxylic acid Compound Fr13623 Benzofuran-2-carboxylic acid Benzofuran-2-carboxylic acid, 97% 496-41-3 C8H5OCOOH Benzofurans Building Blocks Heterocyclic Building Blocks Benzofurans Building Blocks Chemical Synthesis Heterocyclic Building Blocks Carboxylic Acids Furans, Benzofurans & Dihydrobenzofurans Carboxylic Acids Furans, Benzofurans & Dihydrobenzofurans Furan&Benzofuran