PIPETHANATE ETHOBROMIDE

CAS No.
Chemical Name:
PIPETHANATE ETHOBROMIDE
Synonyms
PIPETHANATE ETHOBROMIDE
CBNumber:
CB6281096
Molecular Formula:
C23H30BrNO3
Molecular Weight:
448.39
MDL Number:
MFCD01699810
MOL File:
Mol file

PIPETHANATE ETHOBROMIDE Properties

FDA UNII ZA38L5WD1K

PIPETHANATE ETHOBROMIDE Chemical Properties,Uses,Production

Originator

Panpurol ,Nippon Shinyaku, Japan

Manufacturing Process

Pipethanate hydrochloride is dissolved in water and the solution is made alkaline by adding 10% sodium hydroxide solution. The crystals that are separated are filtered off and recrystallized from dilute ethanol. The monohydrate thereby obtained is dehydrated at 100°C under reduced pressure for 20 minutes. The products that are now in the form of a syrup due to loss of water of crystallization are further dehydrated for 2 days in a desiccator over phosphorus pentoxide whereupon the anhydrous pipethanate is obtained.
3.8 g of the anhydrous pipethanate prepared by the method described is dissolved in 15 cc of acetone, 18 g of purified ethyl bromide is added, and the mixture heated for 8 hours in a sealed tube at 100°C to 110°C. After cooling the crystals are separated and isolated by filtration. They are then washed with acetone to give 5.2 g (95.6%) of pipethanate ethylbromide with a decomposition point of 218°C to 220°C. The crystals are almost pure.

Therapeutic Function

Anticholinergic, Antiulcer

PIPETHANATE ETHOBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

PIPETHANATE ETHOBROMIDE Suppliers

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PIPETHANATE ETHOBROMIDE