3-Quinolineboronic acid
- CAS No.
- 191162-39-7
- Chemical Name:
- 3-Quinolineboronic acid
- Synonyms
- AKOS BRN-0151;CAS:191162-39-7;3-Boronoquinoline;3-Quinolineboronic;RARECHEM AK VD 0023;CHEMBRDG-BB 4003837;3-Quinolineboronica;3-QUINOLINYLBORONI ACID;3-QUINOLYL BORONIC ACID;3-QUINOLINEBORONIC ACID
- CBNumber:
- CB6285069
- Molecular Formula:
- C9H8BNO2
- Molecular Weight:
- 172.98
- MDL Number:
- MFCD02183527
- MOL File:
- 191162-39-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Quinolineboronic acid technical grade | 691909 | 1g | $79.6 |
| 3-Quinolineboronic acid technical grade | 691909 | 5g | $254 |
| Quinoline-3-boronic Acid (contains varying amounts of Anhydride) | Q0080 | 1g | $62 |
| Quinoline-3-boronic Acid (contains varying amounts of Anhydride) | Q0080 | 5g | $249 |
| Quinoline-3-boronic acid ≥95%(Assaybytiration) | 40373 | 1G | $84.83 |
| More product size | |||
| Melting point | 148-155°C |
|---|---|
| Boiling point | 400.3±37.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 4.61±0.30(Predicted) |
| form | Powder |
| color | Light pink or orange to light brown |
| BRN | 8764547 |
| InChI | InChI=1S/C9H8BNO2/c12-10(13)8-5-7-3-1-2-4-9(7)11-6-8/h1-6,12-13H |
| InChIKey | YGDICLRMNDWZAK-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC=CC=2)C=C(B(O)O)C=1 |
| CAS DataBase Reference | 191162-39-7(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280a-P304+P340-P405-P501a-P261-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 36/37/39-26-22-37-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | IRRITANT, KEEP COLD | |||||||||
| HS Code | 29334900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3-Quinolineboronic acid price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 691909 | 3-Quinolineboronic acid technical grade | 191162-39-7 | 1g | $79.6 | 2023-06-20 | Buy |
| Sigma-Aldrich | 691909 | 3-Quinolineboronic acid technical grade | 191162-39-7 | 5g | $254 | 2023-06-20 | Buy |
| TCI Chemical | Q0080 | Quinoline-3-boronic Acid (contains varying amounts of Anhydride) | 191162-39-7 | 1g | $62 | 2026-04-30 | Buy |
| TCI Chemical | Q0080 | Quinoline-3-boronic Acid (contains varying amounts of Anhydride) | 191162-39-7 | 5g | $249 | 2026-04-30 | Buy |
| Chem-Impex | 40373 | Quinoline-3-boronic acid ≥95%(Assaybytiration) | 191162-39-7 | 1G | $84.83 | 2026-05-19 | Buy |
3-Quinolineboronic acid Chemical Properties,Uses,Production
Chemical Properties
light pink or orange to light brown powder
Uses
May contain varying amounts of anhydride.
Uses
3-Quinolineboronic acid can be used as a reactant for: Preparation of P1-substituted symmetry-based human immunodeficiency virus protease inhibitors with antiviral activity against drug-resistant viruses Preparation of heterobiaryls via Suzuki-Miyaura cross-coupling with heteroaryl halides in co
Uses
3-Quinolineboronic acid is a member of a group of boronic acid derivatives that change fluorescence properties once they are bound to sugar molecules. 3-Quinolineboronic acid is also a potential inhibitor of the Staphylococcus aureus NorA efflux pump.
General Description
May contain varying amounts of anhydride
Synthesis
5332-24-1
191162-39-7
General procedure for the synthesis of quinoline-3-boronic acid from 3-bromoquinoline: triisopropyl borate (3.30 mL, 29.06 mmol) and 3-bromoquinoline (3.00 g, 14.49 mmol) were added to a 250 mL two-necked round-bottomed flask under nitrogen protection and dissolved in anhydrous tetrahydrofuran (100 mL). The reaction system was cooled to -78 °C and a 2M hexane solution of n-butyllithium (14.50 mL, 29.00 mmol) was slowly added dropwise through a dropping funnel over a controlled period of 1 hour. After the dropwise addition, the reaction was kept at -78 °C for 2 hours. Subsequently, the acetone/dry ice bath was removed and the reaction system was slowly warmed to 0 °C. The reaction was quenched with 2 M hydrochloric acid solution, followed by adjusting the pH with 2 M sodium bicarbonate solution to 7. The reaction mixture was extracted with ethyl acetate (3 x 100 mL). The organic phases were combined, dried over anhydrous magnesium sulfate and concentrated to dryness under reduced pressure. The product was precipitated by addition of hexane to give a white solid in 80% yield.
References
[1] Dyes and Pigments, 2013, vol. 99, # 1, p. 105 - 115
[2] Synthetic Communications, 2003, vol. 33, # 5, p. 795 - 800
[3] Journal of Organic Chemistry, 2002, vol. 67, # 15, p. 5394 - 5397
[4] Patent: US2009/181941, 2009, A1. Location in patent: Page/Page column 49-50
[5] Journal of the American Chemical Society, 2012, vol. 134, # 28, p. 11667 - 11673
3-Quinolineboronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13902 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29816 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| BAYNOE CHEM CO.,LTD | +86-21-34783353 +8615000719740 | baynoe@baynoe.com | CHINA | 934 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 954 | 58 |
View Lastest Price from 3-Quinolineboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | 3-Quinolineboronic acid
191162-39-7
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-11-18 | 3-Quinolineboronic acid
191162-39-7
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2025-04-04 | 3-Quinolineboronic acid
191162-39-7
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd.
|
-
- 3-Quinolineboronic acid
191162-39-7
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 3-Quinolineboronic acid
191162-39-7
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 3-Quinolineboronic acid
191162-39-7
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
