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ChemicalBook >> CAS DataBase List >>N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Structure
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine structure
CAS No.
102-60-3
Chemical Name:
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
Synonyms
EDTP;QUADROL;Q75;TETRAHYDROXYPROPYL ETHYLENEDIAMINE;EDETOL;entprol;quadroll;Quadrol(R);Q75 / EDTP;EDTP ( Q75)
CBNumber:
CB6287715
Molecular Formula:
C14H32N2O4
Molecular Weight:
292.41
MDL Number:
MFCD00004534
MOL File:
102-60-3.mol
MSDS File:
SDS
Last updated:2026-01-29 15:22:00
Product description Number Pack Size Price
Ethylenediamine-N,N,N′,N′-tetra-2-propanol for synthesis 8.21940 100 mL $47.6
Ethylenediamine-N,N,N′,N′-tetra-2-propanol for synthesis 8.21940 1 L $112
N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine 98% 122262 1l $166
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine >98.0%(T) T0781 25g $24
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine >98.0%(T) T0781 500g $55
More product size
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N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Properties

Melting point 32°C
Boiling point 175-181 °C0.8 mm Hg(lit.)
Density 1.03 g/mL at 20 °C(lit.)
vapor pressure 1 mm Hg ( 20 °C)
refractive index n20/D 1.4812(lit.)
Flash point >230 °F
storage temp. Store below +30°C.
solubility DMSO : ≥ 83.3 mg/mL (284.87 mM)
pka 14.23±0.20(Predicted)
form clear liquid
color Colorless to Almost colorless
Specific Gravity 1.013
PH 10.4 (10g/l, H2O, 20℃)
Water Solubility miscible
Merck 14,3599
BRN 1781143
Cosmetics Ingredients Functions CHELATING
InChI 1S/C14H32N2O4/c1-11(17)7-15(8-12(2)18)5-6-16(9-13(3)19)10-14(4)20/h11-14,17-20H,5-10H2,1-4H3
InChIKey NSOXQYCFHDMMGV-UHFFFAOYSA-N
SMILES CC(O)CN(CCN(CC(C)O)CC(C)O)CC(C)O
LogP -2.08 at 25℃
Indirect Additives used in Food Contact Substances N,N,N',N'-TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINE
CAS DataBase Reference 102-60-3(CAS DataBase Reference)
FDA 21 CFR 177.1680
EWG's Food Scores 1
FDA UNII Q4R969U9FR
EPA Substance Registry System N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine (102-60-3)
UNSPSC Code 12352104
NACRES NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
PPE Eyeshields, Faceshields, Gloves
Hazard Codes  Xi
Risk Statements  43-36
Safety Statements  36/37-37-24-26
WGK Germany  3
RTECS  UB5604000
TSCA  TSCA listed
HS Code  29221980
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Hazardous Substances Data 102-60-3(Hazardous Substances Data)
NFPA 704
0
2 0

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.21940 Ethylenediamine-N,N,N′,N′-tetra-2-propanol for synthesis 102-60-3 100 mL $47.6 2025-07-31 Buy
Sigma-Aldrich 8.21940 Ethylenediamine-N,N,N′,N′-tetra-2-propanol for synthesis 102-60-3 1 L $112 2025-07-31 Buy
Sigma-Aldrich 122262 N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine 98% 102-60-3 1l $166 2025-07-31 Buy
TCI Chemical T0781 N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine >98.0%(T) 102-60-3 25g $24 2025-07-31 Buy
TCI Chemical T0781 N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine >98.0%(T) 102-60-3 500g $55 2025-07-31 Buy
Product number Packaging Price Buy
8.21940 100 mL $47.6 Buy
8.21940 1 L $112 Buy
122262 1l $166 Buy
T0781 25g $24 Buy
T0781 500g $55 Buy

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Chemical Properties,Uses,Production

Description

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine (also known as Quadrol) is a monomer based on ethylenediamine used in the production of polyurethane coatings, adhesives, cosmetics and personal care products. It acts as a chelating agent due to the presence of four hydroxyl groups and as a cross-linking agent due to its two amino groups. It is widely used as a component of polymers and copolymers, especially those designed for UV crosslinked polyurethane polymers, dendritic aminopolymers, conductive polymers, inks and coatings. In addition, Quadrol is also used to produce resins, as well as in the manufacture of surfactants, plasticisers and other chemical products.

Chemical Properties

A clear colorless to pale yellow viscous liquid.  N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine(Tetrahydroxypropyl ethylenediamine) is a chelating agent that binds with metal ions or metallic compounds, preventing them from adhering to a surface (such as skin, hair, or clothing) or causing contamination, such as in the case of trace amounts of iron.

Uses

sweetener

Uses

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine can be used as cross-linking agent and catalyst in the manufacture of urethan foams; in epoxy resin curing; as complexing agent, humectant, emulsifier, plasticizer.

Uses

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine is used as a solvent and preservative. A component of the bacteria-killing substance in sugarcane, it is very alkaline and may be irritating to the skin and mucous membranes. It might also cause skin sensitization.

Definition

ChEBI: Tetrakis(2-hydroxypropyl)ethylenediamine is an amino alcohol.

Application

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine can be used as:
(1) A monomer in the synthesis of covalently cross-linked and amorphous shape memory polyurethane (SMPU) foams that are used in biomedical applications, which includes SMPU actuators for treating ischemic stroke, thrombus removal activated by laser light, self-deployable SMP neuronal electrodes, vascular stents, sutures in microsurgery, ocular implants, bandages, cell manipulation, and cell therapy.
(2) A precursor in the preparation of self-healing CFRPs (carbon fiber reinforced polymer) which are thermally responsive with excellent mechanical properties.
(3) A crosslinking agent to create a hydrogel that is biocompatible and supports the growth of neural cells. Hydrogels are specifically designed to mimic the properties of the extracellular matrix (ECM), in promoting cell proliferation. The purpose of the hydrogel in this context is to act as an extracellular matrix (ECM) substitute, providing a supportive environment for cell growth and guiding cell adhesion and outgrowth.

brand name

Neutrol TE (BASF); Quadrol (BASF).

Flammability and Explosibility

Non flammable

Synthesis

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine can be prepared by the ring-opening addition reaction of ethylenediamine and propylene oxide under the action of a catalyst.

in vitro

Results show that viability of macrophages incubated with Quadrol (N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine) at concentrations of 0.5 mM, 1 mM and 4mM are identical to that for controls. Viability, however, is reduced to 50% of control at concentrations of 16 mM to 32 mM. After four hours, at concentrations of 1 mM and 4 mM, Quadrol produces enhanced spreading of 88% and 80%, respectively, as compared to the control of 28%. Quadrol, at a concentration of 16 mM, shows reduced percentage of spreading of macrophages after four hours. Exposure of macrophages to 1.0 mM or 4.0 mM Quadrol concentrations enhances phagocytic activity, 41% and 57%, respectively, over that of the cells exposed to media alone (34%).

in vivo

On day eight after the implantation, the amount of collagen in the implants of normal mice injected with Quadrol (N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine) exceeds controls by more than 200% (p<0.025). By day 11, the collagen content increases to over 300% higher than controls (p<0.01) and by the end of two weeks after wounding, the time interval typically required for normal and complete wound healing, the collagen accumulated in the implants of the Quadrol-treated mice is about 50% above control (p<0.1). The accumulation of collagen in the implants of Quadrol treated STZ-diabetic mice about 100% above the untreated diabetic control on days 8 to 11. By day 14, the collagen deposition has increased to 200% above the controls (p<0.0 5).

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Preparation Products And Raw materials

Raw materials

Ethylenediamine

Preparation Products

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Suppliers

Global( 342)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Pinestone Fortune International Trading Co., Ltd. 		+86-027-85615902 +86-13971435335 imp.exp8@fengfan.net China 29 58
henan kanbei chemical co.,ltd
+undefined-86-1523780-4566 +undefined15237804566 henankanbeichemical@163.com China 511 58
PT CHEM GROUP LIMITED
+86-85511178; peter68@ptchemgroup.com China 35425 58
Wuhan Bright Chemical Co., Ltd
+86-02785804899 +86-15071395570 alice@brightchemical.com.cn China 93 58
WUHAN JADECHEM INTERNATIONAL TRADE CO.,LTD
+86-83527060; +undefined+86-13972901456 sales03@jadechem-intl.com China 83 58
RongNa Biotechnology Co.,Ltd 		+86-86-13583358881 +8618560316533 Brad@rongnabiotech.com China 3378 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5242 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 deasea125996@gmail.com China 2472 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3692 58
Supplier Advantage
Wuhan Pinestone Fortune International Trading Co., Ltd. 		58
henan kanbei chemical co.,ltd
58
PT CHEM GROUP LIMITED
58
Wuhan Bright Chemical Co., Ltd
58
WUHAN JADECHEM INTERNATIONAL TRADE CO.,LTD
58
RongNa Biotechnology Co.,Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Henan Bao Enluo International TradeCo.，LTD 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58

Related articles

View Lastest Price from N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine pictures 2026-02-17 N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
102-60-3
 US $10.00 / ASSAYS 1ASSAYS 99% 1 ton RongNa Biotechnology Co.,Ltd
Quadrol pictures 2026-01-28 Quadrol
102-60-3
 US $46.00 / mL 99.91% 10g TargetMol Chemicals Inc.
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine pictures 2025-06-27 N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
102-60-3
 US $0.00-0.00 / KG 50KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
  • Quadrol pictures
  • Quadrol
    102-60-3
  • US $46.00 / mL
  • 99.91%
  • TargetMol Chemicals Inc.

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Spectrum

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine(102-60-3)MSN,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine(102-60-3)1HNMRN,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine(102-60-3)IR1N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine(102-60-3)Raman

102-60-3(N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine)Related Search:

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N,N,N'-TRIMETHYLETHYLENEDIAMINE 1-DIETHYLAMINO-2-PROPANOL N,N,N',N'-TETRAKIS(2-HYDROXYETHYL)ETHYLENEDIAMINE N-Methyldipropylamine N,N-Diethylethylenediamine
1-Dimethylamino-2-propanol N,N,N'-TRIETHYLETHYLENEDIAMINE N,N-DIMETHYL-N'-ETHYLETHYLENEDIAMINE N,N,N',N'-TETRAETHYLETHYLENEDIAMINE N,N,N',N'-Tetramethylethylenediamine
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N,N,N',N'-Tetrakis(2-hydroxyprop-1-yl)ethane-1,2-diamine Ethylenediamine-N,N,N',N'-tetra-2-propanol 1,1',1'',1'''-(Ethylenedinitrilo)tetra-2-propanol 1,1',1'',1'''-(Ethane-1,2-diylbis(azanetriyl))tetrakis(propan-2-ol) N,N,N'N'-tetra(2-hydropropyl)ethylene diaMine (EDTP) HexaMethylene traMine tra hydroxy propy chlorid N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine N,N,N,N-Tetrakis(2-Hydroxypropyl)Ethylenediamine98% Q75 Quadrol(R) (Ethylenedinitrilo)tetra-2-propanol, Quadrol(R) (Ethylenedinitril)tetra-2-propanol 1-[2-(Bis(2-hydroxypropyl)amino)ethyl-(2-hydroxypropyl)amino]propan-2-ol N,N,N,'N' -tetra(2-hydropropayl) ethylene diamine EDTP ( Q75) 2-Propanol, 1,1,1,1-(1,2-ethanediyldinitrilo)tetrakis- 1,1’,1’’,1’’’-Ethylenedini N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine, N,N,N,N-Tetrakis(2-hydroxypropyl)ethylenediamine Ethylenediamine-N,N,N',N'-tetra-2-propanol for synthesis 1,1’,1’’,1’’’-(1,2-ethanediyldinitrilo)tetrakis-2-propano 1,1’,1’’,1’’’-(1,2-ethanediyldinitrilo)tetrakis-2-Propanol 1,1’,1’’,1’’’-(ethylenedinitrilo)tetra-2-propano 1,1’,1’’,1’’’-ethane-1,2-diylbisazanediyl-tetrakis-propan-2-ol 1,1’,1’’,1’’’-ethylenedinitrilotetrapropan-2-ol 1’,1’,1’’,1’’’-(1,2-ethanediyldinitrilo)tetrakis-2-propano adekaquadrol entprol n,n,n1,n1-tetrakis n,n,n1,n1-tetrakis(2-hydroxypropyl)ethylenediamine quadroll tetrakis(2-hydroxypropyl)ethylenediamine Tetrakis-[N-(2-hydroxy-propyl)]-ethylenediamine Tetrakis-N-(2-hydroxy-propyl)-ethane-1,2-diamine Tetrakis-N-(2-hydroxy-propyl)-ethylenediamine QUADROL N,N,N',N'-TETRA(2-HYDROXY-PROPYL)ETHYLENEDIAMINE Tetra(3-hydroxypropyl)ethylene diamine EDTP EDETOL ETHYLENEDIAMINE-N,N,N',N'-TETRA-2-PROPANOL (ETHYLENEDINITRILO)TETRA-2-PROPANOL 1,1',1'',1'''-(ETHYLENEDINITRILO)TETRA-2-PROPANOL 1,1',1'',1'''-(ETHYLENEDINITRILO)TETRAKIS(2-PROPANOL) N,N,N',N'-TETRAKIS(2-HYDROXYPROPYL)-*ETH YLENEDIAMIN TETRAHYDROXYPROPYL ETHYLENEDIAMINE EDTP(EDETOL) N;N;N′;N′-TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINE;EDTP N′-Tetrakis(2-hydroxypropyl)ethylenediamine N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine> ETHYLENEDIAMINE-N,N,N',N'-TETRA-2-PROPAN N,N,N',N'-Tetrakis(2-HydroxypropyL N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine ISO 9001：2015 REACH N,N,N’N’-tetrakis (2-Hydroxypropyl) ethylenedianmine N,N,N,N-Tetrakis(2-hydroxypropyl)ethylenediamine EDTP ( Q75) Q75 / EDTP 1,1',1'',1'''-(Ethane-1,2-diylbis(azanetriyl) N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine, ≥ 98.0% Betolin Q 40 N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine