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PGK

CAS No.
Chemical Name:
PGK
Synonyms
PGK;cGK;PKG;AAT8;CGKI;cGK1;cGK 1;PKG Iα;MGC71944;FLJ36117
CBNumber:
CB62898623
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD00285623
MOL File:
Mol file
Last updated:2026-01-13 11:23:08

PGK Properties

storage temp. -20°C
form buffered aqueous glycerol solution
Specific Activity 663-897nmol/min·mg
UNSPSC Code 12352200
NACRES NA.32

SAFETY

Risk and Safety Statements

WGK Germany  WGK 1
Storage Class 10 - Combustible liquids

PGK price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R8282 PRKG1, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution 10 μg $433 2026-04-30 Buy
Product number Packaging Price Buy
R8282 10 μg $433 Buy

PGK Chemical Properties, Uses, Production

Biological Activity

PRKG1 is a homodimer, with each monomer containing a regulatory cGMP-binding domain and a catalytic domain. By Northern blot analysis PRKG1 was shown to be expressed at highest levels in bladder, uterus, adrenal gland, and fallopian tube. PRKG1 plays an important stimulatory role in platelet activation. Expression of recombinant PRKG1 in a reconstituted cell model enhanced von Willebrand factor-induced activation of the platelet integrin alpha-IIb/beta-3. Prkg1 knockout mice showed impaired platelet responses to VWF or low doses of thrombin and prolonged bleeding time. Human platelet aggregation induced by VWF or low-dose thrombin was inhibited by PRKG1 inhibitors but enhanced by cGMP.

PGK Preparation Products And Raw materials

Raw materials

Preparation Products

PGK Suppliers

Global Suppliers ( 7)
Supplier Tel Email Country ProdList Advantage
Shanghai Huzhen Industrial Co., LTD 021-60345367 13916550749 sales@shzbio.com China 9965 58
Shanghai Bohu Biological Technology Co., Ltd. 57763112 18930344717 3004987436@qq.com China 9989 58
Shanghai Yansheng Industrial Co., Ltd. 021-59989018 15201736385 3004965319@qq.com China 8248 58
DKFZp686K042 FLJ36117 MGC71944 PGK CGKI PRKG1, active, GST tagged human PKG Iα AAT8 cGK cGK 1 cGK1 cGKI-alpha cGKI-BETA PKG