Poly(2-hydroxyethyl methacrylate)
- CAS No.
- 25249-16-5
- Chemical Name:
- Poly(2-hydroxyethyl methacrylate)
- Synonyms
- POLY-HEMA;POLY(2-HEMA);12%solutioninethanol;CELLFORM(TM) POLYMER;Poly(2-HEMA), Poly-HEMA;polyhydroxyethylmethacrylate;Poly(2-hydroxyethyl methacrylate);2-HYDROXYETHYL METHACRYLATE POLYMER;Poly(2-hydroxyethylmethacrylate)powder;2-hydroxyethyl methacrylate homopolymer
- CBNumber:
- CB6301127
- Molecular Formula:
- C6H10O3
- Molecular Weight:
- 130.14
- MDL Number:
- MFCD00084374
- MOL File:
- 25249-16-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Density | 1.15 g/mL at 25 °C(lit.) |
|---|---|
| Tg | 55 |
| refractive index | 1.5119 |
| storage temp. | 4°C, away from moisture |
| solubility | ethanol: 120 mg/mL |
| form | powder |
| color | White to off-white |
| biological source | synthetic (organic) |
| Cosmetics Ingredients Functions | BINDING |
| InChI | 1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3 |
| InChIKey | WOBHKFSMXKNTIM-UHFFFAOYSA-N |
| SMILES | CC(=C)C(=O)OCCO |
| Indirect Additives used in Food Contact Substances | POLY(2-HYDROXYETHYL METHACRYLATE) |
| FDA 21 CFR | 175.105 |
| EWG's Food Scores | 1 |
| EPA Substance Registry System | 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, homopolymer (25249-16-5) |
| UNSPSC Code | 12352207 |
| NACRES | NA.75 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| Storage Class | 11 - Combustible Solids |
Poly(2-hydroxyethyl methacrylate) price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 192066 | Poly(2-hydroxyethyl methacrylate) average Mv 300,000, crystalline | 25249-16-5 | 10g | $216 | 2026-04-30 | Buy |
| Sigma-Aldrich | 192066 | Poly(2-hydroxyethyl methacrylate) average Mv 300,000, crystalline | 25249-16-5 | 25g | $419 | 2026-04-30 | Buy |
| ChemScene | CS-1234328 | Poly(2-hydroxyethyl methacrylate) Mv 300000 | 25249-16-5 | 1g | $70 | 2026-06-04 | Buy |
| ChemScene | CS-1234328 | Poly(2-hydroxyethyl methacrylate) Mv 300000 | 25249-16-5 | 5g | $217 | 2026-06-04 | Buy |
| ChemScene | CS-1234328 | Poly(2-hydroxyethyl methacrylate) Mv 300000 | 25249-16-5 | 10g | $357 | 2026-06-04 | Buy |
Poly(2-hydroxyethyl methacrylate) Chemical Properties, Uses, Production
Uses
Poly(2-hydroxyethyl methacrylate) has been used:
- as a nonadhesive substrate in the preparation of single cell suspensions
- to implant into mice cornea for corneal micropocket assay
- to coat the well plates for sphere assay using adipose-derived mesenchymal stem cells
Uses
pHEMA scaffolds are used in tissue engineering. It can be used in hydrogels for biomedical applications, as sorbents for metal ions.pHEMA has been used in applications such as soft contact lenses, in drug delivery systems, and in kidney dialysis membranes.Nanoparticles of pHEMA may be employed as a carrier for controlled delivery of anticancer and antitumor drugs.
Definition
ChEBI: An acrylate macromolecule, composed of repeating 2-hydroxyethyl 2-methylpropanoate units.
General Description
Solid Poly(2-hydroxyethyl methacrylate) (pHEMA) is brittle, while pHEMA hydrogel is a soft material. Glass transition temperature for pHEMA hydrogels is reduced by increasing a content of water in the matrix. Macromolecular properties in pHEMA are characterized by non-covalent interactions of hydrogen-bonds among the polymer chains as well as the hydrated water molecules. The presence of polar groups of hydroxyl and carboxyl on each repeat unit makes this polymer compatible with water. The hydrophobic a-methyl groups of the backbone convey hydrolytic stability to the polymer and enhance mechanical strength of the polymer matrix.
Biochem/physiol Actions
Poly(2-hydroxyethyl methacrylate) is an acrylic compound and has dental usage. It is mainly used to inhibit cell adhesion to growth surfaces in culture vessels.
Solubility in organics
DMF, methanol, methyl cellosolve
Poly(2-hydroxyethyl methacrylate) Preparation Products And Raw materials
Raw materials
Preparation Products
Poly(2-hydroxyethyl methacrylate) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Wanna Juhe Polymer Technology Co., Ltd | 13661897211 | hecongze@wannapolymer.com | China | 113 | 58 |
| Jinan Ruiyao Mingzhi Medical Technology Co., Ltd | 15662630077 15662630077 | 958367155@qq.com | China | 570 | 58 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Shanghai Qianhao Biotechnology Co., LTD | 13524877553 | 13524877553@163.com | China | 122 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| HangZhou YuHao Chemical Technology Co., Ltd. | 0571-82693216 | info@yuhaochemical.com | China | 1999 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
View Latest Price from Poly(2-hydroxyethyl methacrylate) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-25 | poly(2-hydroxyethyl methacrylate)
25249-16-5
|
$3.90-5.90 | 1KG | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | ||
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2026-08-20 | POLY(2-HYDROXYETHYL METHACRYLATE)
25249-16-5
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
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2026-03-20 | POLY(2-HYDROXYETHYL METHACRYLATE)
25249-16-5
|
$10.00 | 100KG | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-

- poly(2-hydroxyethyl methacrylate)
25249-16-5
- $3.90-5.90
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- POLY(2-HYDROXYETHYL METHACRYLATE)
25249-16-5
- $1.10
- 99.00%
- Dideu Industries Group Limited
-

- POLY(2-HYDROXYETHYL METHACRYLATE)
25249-16-5
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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