ChemicalBook >> CAS DataBase List >>ETHYL 3-AMINOCROTONATE
ETHYL 3-AMINOCROTONATE
- CAS No.
- 626-34-6
- Chemical Name:
- ETHYL 3-AMINOCROTONATE
- Synonyms
- (Z)-3-aminobut-2-enoate;(Z)-ETHYL 3-AMINOBUT-2-ENOATE;Ethyl (2Z)-3-amino-2-butenoate;AURORA KA-7376;Ethyl 3-aMinocroton;3-amino-2-hexenoate;ETHYL 3-AMINOCROTONA;Impurity of nifedipine;3-Aminocrotonate ethyl;Ethyl (Z)-3-aminocrotonate
- CBNumber:
- CB6302533
- Molecular Formula:
- C6H11NO2
- Molecular Weight:
- 129.16
- MDL Number:
- MFCD02730138
- MOL File:
- 626-34-6.mol
- MSDS File:
- SDS
Last updated:2026-01-13 11:23:41
| Product description | Number | Pack Size | Price |
| Ethyl 3-aminocrotonate 98% | E10807 | 100g | $60.1 |
| Ethyl 3-aminocrotonate 98% | E10807 | 500g | $154 |
| (Z)-Ethyl 3-aminobut-2-enoate 97% | E92236 | 5g | $14 |
| (Z)-Ethyl 3-aminobut-2-enoate 97% | E92236 | 10g | $18 |
| (Z)-Ethyl 3-aminobut-2-enoate 97% | E92236 | 25g | $20 |
| More product size | |||
| Melting point | 33-35 °C (lit.) |
|---|---|
| Boiling point | 210-215 °C (lit.) |
| Density | 1.022 g/mL at 25 °C (lit.) |
| refractive index | 1.4990 |
| Flash point | 207 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 5.32±0.70(Predicted) |
| Appearance | Off-white to light yellow <33°C Solid,>35°C Liquid |
| Water Solubility | Soluble in water (26 g/L) (25°C). |
| Sensitive | Air & Moisture Sensitive & Hygroscopic |
| BRN | 471284 |
| InChI | InChI=1S/C6H11NO2/c1-3-9-6(8)4-5(2)7/h4H,3,7H2,1-2H3/b5-4- |
| InChIKey | YPMPTULBFPFSEQ-PLNGDYQASA-N |
| SMILES | C(OCC)(=O)/C=C(\N)/C |
| LogP | 0.390 (est) |
| CAS DataBase Reference | 626-34-6(CAS DataBase Reference) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H335 | |||||||||
| Precautionary statements | P260-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34-36/37 | |||||||||
| Safety Statements | 26-27-28-36/37/39-45 | |||||||||
| RIDADR | UN 3263 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29224999 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Corr. 1B STOT SE 3 |
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| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
ETHYL 3-AMINOCROTONATE price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E10807 | Ethyl 3-aminocrotonate 98% | 626-34-6 | 100g | $60.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | E10807 | Ethyl 3-aminocrotonate 98% | 626-34-6 | 500g | $154 | 2023-06-20 | Buy |
| Synthonix | E92236 | (Z)-Ethyl 3-aminobut-2-enoate 97% | 626-34-6 | 5g | $14 | 2026-05-06 | Buy |
| Synthonix | E92236 | (Z)-Ethyl 3-aminobut-2-enoate 97% | 626-34-6 | 10g | $18 | 2026-05-06 | Buy |
| Synthonix | E92236 | (Z)-Ethyl 3-aminobut-2-enoate 97% | 626-34-6 | 25g | $20 | 2026-05-06 | Buy |
ETHYL 3-AMINOCROTONATE Chemical Properties,Uses,Production
Uses
Ethyl 3-aminocrotonate, is used as an intermediate in organic synthesis. It is also used as an active ingredient in pharmaceutical synthesis and feed auxiliary agent. It is also used as an active pharmaceutical intermediate.
Synthesis
141-97-9
626-34-6
Example 9: Preparation of ethyl 3-aminocrotonate was carried out using continuous flow experiments. The experiments were carried out in a 1.58 mm OD SS316 tubular reactor. By using a simple T-mixer and a 1 m long reactor, ethyl acetoacetate was mixed with ammonia (25% solution) in a ratio of 1:3 with a residence time of 22 min. The yield of the product ethyl 3-aminocrotonate was 94% at 50 °C.
References
[1] Comptes Rendus Chimie, 2011, vol. 14, # 5, p. 511 - 515
[2] Patent: WO2012/147103, 2012, A2. Location in patent: Page/Page column 7
[3] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986, vol. 35, p. 1438 - 1442
[4] Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986, # 7, p. 1586 - 1592
[5] European Journal of Medicinal Chemistry, 2018, vol. 155, p. 946 - 960
ETHYL 3-AMINOCROTONATE Preparation Products And Raw materials
Global( 271)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Ever Galaxy Chemical Co.,Ltd | +86-0527-81083685; +8618602515822 | info@egchemical.com | China | 79 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13903 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29817 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3980 | 58 |
View Lastest Price from ETHYL 3-AMINOCROTONATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | Ethyl 3-aminocrotonate
626-34-6
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-07-13 | ETHYL 3-AMINOCROTONATE
626-34-6
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-10 | ETHYL 3-AMINOCROTONATE
626-34-6
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Ethyl 3-aminocrotonate
626-34-6
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- ETHYL 3-AMINOCROTONATE
626-34-6
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- ETHYL 3-AMINOCROTONATE
626-34-6
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
626-34-6(ETHYL 3-AMINOCROTONATE)Related Search:
Isopropyl 3-aminocrotonate
Methyl 3-aminocrotonate
3-Aminocrotononitrile
Ethyl 2-amino-1-cyclopentene-1-carboxylate
Ethyl 3-amino-4,4,4-trifluorocrotonate
tert-Butyl cyanoacetate
Ethyl crotonate
3-Amino-2-butenoic acid ethyl ester
Crotonic acid
Crotonic acid
2,2-DIMETHYL-5-(2-HEXAHYDROAZEPINYLIDENE)-1,3-DIOXAN-4,6-DIONE
2,2-DIMETHYL-5-(2-TETRAHYDROPYRROLYLIDENE)-1,3-DIOXANE-4,6-DIONE
5-[1-AMINO-2-(4-CHLOROPHENYL)ETHYLIDENE]-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE
ETHYL 2-(3-OXO-2-PIPERAZINYLIDENE)ACETATE
2,2-Dimethyl-5-(2-piperidinylidene)-1,3-dioxane-4,6-dione
1of4
(Z)-ETHYL 3-AMINOBUT-2-ENOATE
3-AMINOCROTONIC ACIDETHYL ESTER
Ethyl 3-aminocrotonate, 98+%
2-Butenoic acid, 3-amino-, ethyl ester, (2Z)-
trans-3-amino-but-2-enoic acid ethyl ester
AURORA KA-7376
(2Z)-3-Amino-2-butenoic acid ethyl ester
(Z)-3-Aminocrotonic acid ethyl
(Z)-3-Aminocrotonic acid ethyl ester
Ethyl (Z)-3-amino-2-butenoate
ETHYL 3-AMINOCROTONA
Ethyl (Z)-3-aminocrotonate
Ethyl 3-aMinocroton
Ethyl 3-aminocrotonate 98%
(Z)-Ethyl 3-aminocrotonate
Ethyl(Z)-3-aminobut-2-enoate
3-amino-2-hexenoate
Ethyl (2Z)-3-aminocrotonate
Ethyl 3-Aminocrotonate (2 x 200 mg) (Ethyl (Z)-3-aminobut-2-enoate)
Impurity of nifedipine
(Z)-Ethyl 3-aminobut-2-enoate - [E92236]
Ethyl (2Z)-3-amino-2-butenoate
(Z)-3-aminobut-2-enoate
3-Aminocrotonate ethyl ester
3-Aminocrotonate ethyl
626-34-6
CH3CNH2CHCO2C2H5
C6H12NO2
Building Blocks
Carbonyl Compounds
C6 to C7
Organic Building Blocks
Esters
Starting Raw Materials & Intermediates
Organic acids
C6 to C7
Carbonyl Compounds
Esters
