2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE
- CAS No.
- 239087-06-0
- Chemical Name:
- 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE
- Synonyms
- OTF-BYM-6F;RARECHEM AL BW 0538;elagolix intermediate 1;2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE;2-Chloro-6-(trifluoromethyl)benzylamine,97%;2-Fluoro-6-(trifluoromethyl)benzenemethanamine;(2-fluoro-6-(trifluoroMethyl)phenyl)MethanaMine;Benzenemethanamine, 2-fluoro-6-(trifluoromethyl)-;2-Chloro-6-(trifluoroMethyl)benzylaMine, JRD, 97%;1-[2-Fluoro-6-(trifluoromethyl)phenyl]methanamine
- CBNumber:
- CB6303868
- Molecular Formula:
- C8H7F4N
- Molecular Weight:
- 193.14
- MDL Number:
- MFCD00061165
- MOL File:
- 239087-06-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Fluoro-6-(trifluoromethyl)benzylamine | F594795 | 5g | $315 |
| 2-Fluoro-6-(trifluoromethyl)benzylamine | F594795 | 500mg | $65 |
| 2-Fluoro-6-(trifluoromethyl)benzylamine 98% | 3830-3-26 | 5G | $105 |
| 2-Fluoro-6-(trifluoromethyl)benzylamine 98% | 3830-3-26 | 1g | $35 |
| 2-Fluoro-6-(trifluoromethyl)benzylamine | 1682AB | 1g | $47 |
| More product size | |||
| Boiling point | 173.2±35.0 °C(Predicted) |
|---|---|
| Density | 1.312±0.06 g/cm3(Predicted) |
| refractive index | 1.4925 |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| pka | 7.84±0.10(Predicted) |
| form | liquid |
| color | Clear, colourless |
| Sensitive | Air Sensitive |
| InChI | InChI=1S/C8H7F4N/c9-7-3-1-2-6(5(7)4-13)8(10,11)12/h1-3H,4,13H2 |
| InChIKey | FCYVKQRWNQRCFE-UHFFFAOYSA-N |
| SMILES | C1(CN)=C(C(F)(F)F)C=CC=C1F |
| FDA UNII | VTH5K8PW7U |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H314-H318 | |||||||||
| Precautionary statements | P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| Hazard Note | Corrosive/Store under nitrogen | |||||||||
| HazardClass | 8 | |||||||||
| HS Code | 2921490090 | |||||||||
| NFPA 704 |
|
2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | F594795 | 2-Fluoro-6-(trifluoromethyl)benzylamine | 239087-06-0 | 5g | $315 | 2021-12-16 | Buy |
| TRC | F594795 | 2-Fluoro-6-(trifluoromethyl)benzylamine | 239087-06-0 | 500mg | $65 | 2021-12-16 | Buy |
| SynQuest Laboratories | 3830-3-26 | 2-Fluoro-6-(trifluoromethyl)benzylamine 98% | 239087-06-0 | 5G | $105 | 2021-12-16 | Buy |
| SynQuest Laboratories | 3830-3-26 | 2-Fluoro-6-(trifluoromethyl)benzylamine 98% | 239087-06-0 | 1g | $35 | 2021-12-16 | Buy |
| AK Scientific | 1682AB | 2-Fluoro-6-(trifluoromethyl)benzylamine | 239087-06-0 | 1g | $47 | 2021-12-16 | Buy |
2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE Chemical Properties,Uses,Production
Chemical Properties
Colorless to pale yellow liquid
Uses
(2-Fluoro-6-(trifluoromethyl)phenyl)methanamine Hydrochloride is used in preparation method and application of Elagolix intermediate and its salts.
Synthesis
581072-15-3
239087-06-0
In a 5L three-neck flask, Intermediate B (207.0 g, 1.0 mol) was added. Ethanol (500 mL), water (200 mL) and concentrated hydrochloric acid (400 mL) were added sequentially to the reaction system and stirred for 0.5 h. The reaction mixture was cooled to 0-5 °C. Zinc powder (390 g, 6.0 mol) was slowly added while maintaining the temperature at 0-5 °C, and the rate of addition was controlled to ensure that the reaction temperature did not exceed 5 °C. After the addition of zinc powder, the reaction system was warmed up to 80-85 °C and the reaction was maintained at this temperature for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature, filtered and the filter cake was washed with ethanol (300 mL). The filtrates were combined and concentrated under reduced pressure until a significant amount of solid precipitated. The solid was collected by filtration and dried to give the target product 2-fluoro-6-(trifluoromethyl)benzylamine (169.5 g, 87.8% yield).
References
[1] Patent: CN107935863, 2018, A. Location in patent: Paragraph 0048-0051; 0055-0056; 0064-0065
2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30227 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
View Lastest Price from 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-17 | 1-[2-Fluoro-6-(trifluoromethyl)phenyl]methanamine
239087-06-0
|
US $22.00-88.00 / kg | 1kg | 99% | 50kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
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2020-01-09 | 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE
239087-06-6
|
US $2.00 / KG | 1KG | 98% | 1kg, 5kg ,50kg | Career Henan Chemical Co | |
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2019-07-06 | 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE
239087-06-0
|
US $1.00 / KG | 1G | 99% | 100KG | Career Henan Chemical Co |
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![1-[2-Fluoro-6-(trifluoromethyl)phenyl]methanamine pictures](/ProductImageEN1/2025-06/Small/e578ed5a-74a2-4d42-a8fe-91dca7279a7f.png)
- 1-[2-Fluoro-6-(trifluoromethyl)phenyl]methanamine
239087-06-0
- US $22.00-88.00 / kg
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE
239087-06-6
- US $2.00 / KG
- 98%
- Career Henan Chemical Co
-

- 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE
239087-06-0
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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