ChemicalBook >> CAS DataBase List >>2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE

2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE

CAS No.
239087-06-0
Chemical Name:
2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE
Synonyms
OTF-BYM-6F;RARECHEM AL BW 0538;elagolix intermediate 1;2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE;2-Chloro-6-(trifluoromethyl)benzylamine,97%;2-Fluoro-6-(trifluoromethyl)benzenemethanamine;(2-fluoro-6-(trifluoroMethyl)phenyl)MethanaMine;Benzenemethanamine, 2-fluoro-6-(trifluoromethyl)-;2-Chloro-6-(trifluoroMethyl)benzylaMine, JRD, 97%;1-[2-Fluoro-6-(trifluoromethyl)phenyl]methanamine
CBNumber:
CB6303868
Molecular Formula:
C8H7F4N
Molecular Weight:
193.14
MDL Number:
MFCD00061165
MOL File:
239087-06-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:30
Product description Number Pack Size Price
2-Fluoro-6-(trifluoromethyl)benzylamine F594795 5g $315
2-Fluoro-6-(trifluoromethyl)benzylamine F594795 500mg $65
2-Fluoro-6-(trifluoromethyl)benzylamine 98% 3830-3-26 5G $105
2-Fluoro-6-(trifluoromethyl)benzylamine 98% 3830-3-26 1g $35
2-Fluoro-6-(trifluoromethyl)benzylamine 1682AB 1g $47
More product size

2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE Properties

Boiling point 173.2±35.0 °C(Predicted)
Density 1.312±0.06 g/cm3(Predicted)
refractive index 1.4925
storage temp. Keep in dark place,Inert atmosphere,2-8°C
pka 7.84±0.10(Predicted)
form liquid
color Clear, colourless
Sensitive Air Sensitive
InChI InChI=1S/C8H7F4N/c9-7-3-1-2-6(5(7)4-13)8(10,11)12/h1-3H,4,13H2
InChIKey FCYVKQRWNQRCFE-UHFFFAOYSA-N
SMILES C1(CN)=C(C(F)(F)F)C=CC=C1F
FDA UNII VTH5K8PW7U

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Warning
Hazard statements  H314-H318
Precautionary statements  P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a
Hazard Codes  C
Risk Statements  36/37/38
Safety Statements  26-36
Hazard Note  Corrosive/Store under nitrogen
HazardClass  8
HS Code  2921490090
NFPA 704
0
3 0

2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F594795 2-Fluoro-6-(trifluoromethyl)benzylamine 239087-06-0 5g $315 2021-12-16 Buy
TRC F594795 2-Fluoro-6-(trifluoromethyl)benzylamine 239087-06-0 500mg $65 2021-12-16 Buy
SynQuest Laboratories 3830-3-26 2-Fluoro-6-(trifluoromethyl)benzylamine 98% 239087-06-0 5G $105 2021-12-16 Buy
SynQuest Laboratories 3830-3-26 2-Fluoro-6-(trifluoromethyl)benzylamine 98% 239087-06-0 1g $35 2021-12-16 Buy
AK Scientific 1682AB 2-Fluoro-6-(trifluoromethyl)benzylamine 239087-06-0 1g $47 2021-12-16 Buy
Product number Packaging Price Buy
F594795 5g $315 Buy
F594795 500mg $65 Buy
3830-3-26 5G $105 Buy
3830-3-26 1g $35 Buy
1682AB 1g $47 Buy

2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE Chemical Properties,Uses,Production

Chemical Properties

Colorless to pale yellow liquid

Uses

(2-Fluoro-6-(trifluoromethyl)phenyl)methanamine Hydrochloride is used in preparation method and application of Elagolix intermediate and its salts.

Synthesis

Benzaldehyde, 2-fluoro-6-(trifluoromethyl)-, oxime

581072-15-3

2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE

239087-06-0

In a 5L three-neck flask, Intermediate B (207.0 g, 1.0 mol) was added. Ethanol (500 mL), water (200 mL) and concentrated hydrochloric acid (400 mL) were added sequentially to the reaction system and stirred for 0.5 h. The reaction mixture was cooled to 0-5 °C. Zinc powder (390 g, 6.0 mol) was slowly added while maintaining the temperature at 0-5 °C, and the rate of addition was controlled to ensure that the reaction temperature did not exceed 5 °C. After the addition of zinc powder, the reaction system was warmed up to 80-85 °C and the reaction was maintained at this temperature for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature, filtered and the filter cake was washed with ethanol (300 mL). The filtrates were combined and concentrated under reduced pressure until a significant amount of solid precipitated. The solid was collected by filtration and dried to give the target product 2-fluoro-6-(trifluoromethyl)benzylamine (169.5 g, 87.8% yield).

References

[1] Patent: CN107935863, 2018, A. Location in patent: Paragraph 0048-0051; 0055-0056; 0064-0065

60611-24-7
239087-06-0
Synthesis of 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE from 2-FLUORO-6-(TRIFLUOROMETHYL)BENZALDEHYDE
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View Lastest Price from 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-[2-Fluoro-6-(trifluoromethyl)phenyl]methanamine pictures 2026-04-17 1-[2-Fluoro-6-(trifluoromethyl)phenyl]methanamine
239087-06-0
US $22.00-88.00 / kg 1kg 99% 50kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE pictures 2020-01-09 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE
239087-06-6
US $2.00 / KG 1KG 98% 1kg, 5kg ,50kg Career Henan Chemical Co
2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE pictures 2019-07-06 2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE
239087-06-0
US $1.00 / KG 1G 99% 100KG Career Henan Chemical Co
2-FLUORO-6-(TRIFLUOROMETHYL)BENZYLAMINE 2-Chloro-6-(trifluoroMethyl)benzylaMine, JRD, 97% 2-(Aminomethyl)-3-fluorobenzotrifluoride, [2-Fluoro-6-(trifluoromethyl)phenyl]methylamine (2-fluoro-6-(trifluoroMethyl)phenyl)MethanaMine (2-fluoro-6-(trifluoroMethyl)phenyl)MethanaMine hydrochloride elagolix intermediate 1 1-[2-Fluoro-6-(trifluoromethyl)phenyl]methanamine OTF-BYM-6F RARECHEM AL BW 0538 2-Fluoro-6-(trifluoromethyl)benzenemethanamine Benzenemethanamine, 2-fluoro-6-(trifluoromethyl)- 2-Chloro-6-(trifluoromethyl)benzylamine,97% Elagolix Impurity 2 2-Fluoro-6-(trifluoromethyl)benzylamine 239087-06-0 239087-06-6 C8H7F4NHCl C9H10NF3 Amine