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Butyryl chloride

CAS No.
141-75-3
Chemical Name:
Butyryl chloride
Synonyms
N-BUTYRYL CHLORIDE;butyryl;BUTANOYL CHLORIDE;N-BUTYLVINYLETHER;BUTYRIC ACID CHLORIDE;N-Butyryl;Butyrylchlorid;butyricchloride;Butyric chloride;BUTYRYL CHLORIDE
CBNumber:
CB6309567
Molecular Formula:
C4H7ClO
Molecular Weight:
106.55
MDL Number:
MFCD00000752
MOL File:
141-75-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-01 16:59:24
Product description Number Pack Size Price
Butyryl chloride for synthesis 8.01977 250ML $60.1
Butyryl chloride for synthesis 8.01977 1L $165
Butyryl chloride 98% 109614 250g $69.4
Butyryl chloride 98% 109614 1kg $151
Butyryl Chloride >98.0%(GC)(T) B0770 25g $17
More product size

Butyryl chloride Properties

Melting point −89 °C(lit.)
Boiling point 102 °C(lit.)
Density 1.026 g/mL at 25 °C(lit.)
vapor density 3.7 (vs air)
vapor pressure 39 hPa (20 °C)
refractive index n20/D 1.412(lit.)
RTECS EM0595000
Flash point 71 °F
storage temp. Store below +30°C.
solubility Miscible with ether.
form Liquid
color Clear slightly yellow
Odor pungent odor
explosive limit 2.5-7.3%(V)
Water Solubility decomposes
FreezingPoint -89℃
Sensitive Moisture Sensitive
Merck 14,1598
BRN 605395
InChI 1S/C4H7ClO/c1-2-3-4(5)6/h2-3H2,1H3
InChIKey DVECBJCOGJRVPX-UHFFFAOYSA-N
SMILES CCCC(Cl)=O
LogP 0.51 at 25℃
CAS DataBase Reference 141-75-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 2XVM8E16IR
NIST Chemistry Reference Butanoyl chloride(141-75-3)
EPA Substance Registry System Butanoyl chloride (141-75-3)
UNSPSC Code 12352106
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS06,GHS09
Signal word  Danger
Hazard statements  H225-H302-H314-H331-H410
Precautionary statements  P210-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  F,C
Risk Statements  11-34
Safety Statements  16-23-26-36-45
RIDADR  UN 2353
WGK Germany  1
13
Autoignition Temperature 280 °C
TSCA  TSCA listed
HS Code  2915 90 70
HazardClass  3
PackingGroup  II
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 2
Eye Dam. 1
Flam. Liq. 2
Skin Corr. 1B
Hazardous Substances Data 141-75-3(Hazardous Substances Data)
Limited Quantities 1.0 L (0.3 gallon) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
3
3 0

Butyryl chloride price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.01977 Butyryl chloride for synthesis 141-75-3 250ML $60.1 2026-04-30 Buy
Sigma-Aldrich 8.01977 Butyryl chloride for synthesis 141-75-3 1L $165 2026-04-30 Buy
Sigma-Aldrich 109614 Butyryl chloride 98% 141-75-3 250g $69.4 2026-04-30 Buy
Sigma-Aldrich 109614 Butyryl chloride 98% 141-75-3 1kg $151 2026-04-30 Buy
TCI Chemical B0770 Butyryl Chloride >98.0%(GC)(T) 141-75-3 25g $17 2026-04-30 Buy
Product number Packaging Price Buy
8.01977 250ML $60.1 Buy
8.01977 1L $165 Buy
109614 250g $69.4 Buy
109614 1kg $151 Buy
B0770 25g $17 Buy

Butyryl chloride Chemical Properties,Uses,Production

Chemical Properties

Butyryl chloride is a colorless to light yellow liquid with a strong pungent odor. It undergoes vigorous hydrolysis with water; decomposes in water; soluble in almost aprotic organic solvents. It is used as an intermediate for organic synthesis for the preparation of pharmaceuticals, agrochemicals, dyes, cellulose esters, and peroxide compounds.

Uses

Butyryl chloride is used as an intermediate for the synthesis of active pharmaceutical ingredients benzoyl peroxide, t-butyl perbenzoate, and benzophenone. It is also used as an acylation reagent. Further, it is used in the preparation of peroxides such as benzoyl peroxide, benzophenone and t-butyl perbenzoate. In addition to this, it is involved in the preparation of chromones and antiproliferative agents.
Butyryl chloride has been used to esterify wood meal dissolved in the ionic liquid, 1-butyl-3-methylimidazolium chloride.

General Description

A clear colorless liquid with a sharp odor. Slightly denser than water. Flash point near 20°F. Severely irritates skin, eyes, and mucous membranes. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Fumes in air. Decomposes exothermically in water to give corrosive hydrochloric acid.

Reactivity Profile

Butyryl chloride slowly dissolves in water with decomposition and formation of a weakly acidic solution. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Health Hazard

Extremely destructive to the mucous membranes, upper respiratory tract, eyes, and skin. Inhalation may cause death as a result of spasm, inflammation and edema of the larynx and bronchi, chemical pneumonitis, and pulmonary edema. Symptoms of exposure include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.

Fire Hazard

Special Hazards of Combustion Products: Emits toxic fumes of chlorine gas

Flammability and Explosibility

Flammable

Purification Methods

Check IR to see if there is a significant peak at 3000-3500 cm-1 (br) for OH. If OH is present then reflux with less than one mole equivalent of SOCl2 for 1hour and distil directly. The fraction boiling between 85-100o is then refractionated at atmospheric pressure. Keep all apparatus free from moisture and store the product in sealed glass ampoules under N2. LACHRYMATORY; handle in a good fume hood. [Hefferich & Schaeffer Org Synth Coll Vol I 147 1941, Beilstein 2 IV 803.]

Global( 388)Suppliers
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Hebei Chuanghai Biotechnology Co., Ltd
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View Lastest Price from Butyryl chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Butyryl Chloride pictures 2026-03-20 Butyryl Chloride
141-75-3
US $10.00 / kg 1kg 99.5% 100 TON Hebei Chuanghai Biotechnology Co., Ltd
Butyryl chloride pictures 2025-12-25 Butyryl chloride
141-75-3
US $0.00 / KG 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
Butyryl chloride pictures 2025-08-20 Butyryl chloride
141-75-3
US $0.00-0.00 / kg 1kg 99.99% 20 tons Chongqing Soarwin Technology Co., Ltd
  • Butyryl Chloride pictures
  • Butyryl Chloride
    141-75-3
  • US $10.00 / kg
  • 99.5%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • Butyryl chloride pictures
  • Butyryl chloride
    141-75-3
  • US $0.00-0.00 / kg
  • 99.99%
  • Chongqing Soarwin Technology Co., Ltd
BUTYRIC ACID CHLORIDE BUTYROYL CHLORIDE BUTYRYL CHLORIDE BUTANOYL CHLORIDE N-BUTYRIC ACID CHLORIDE N-BUTYROYL CHLORIDE N-BUTYRYL CHLORIDE N-BUTANOYL CHLORIDE AKOS BBS-00003913 TETRANOYL CHLORIDE Butyric chloride BUTYRYL CHLORIDE FOR SYNTHESIS Butyryl chloride(Butanoyl chloride) BUTIRYL CHLORIDE n-Butyryl chloride Butanoyl chloride butyricchloride butyryl Butyrylchlorid BUTYRYL CHLORIDE, 99+% N-Butyryl N-BUTYLVINYLETHER BUTYRYL CHLORIDE extrapure N-butyrylchlovide Butyryl Chloride > 1. n-Butyryl Chloride Butyryl chloride, 98% 141-75-3 14-75-3 C3H7COCl C2H5CH2COCl CH3CH22COCl CH3CH2CH2COCl Acid Halides Building Blocks Carbonyl Compounds Organic Building Blocks Pharmaceutical Intermediates Organics Acid Halides Carbonyl Compounds Organic Building Blocks pharmaceutical, pesticide intermediate