HUMAN PF-4
- CAS No.
- 37270-94-3
- Chemical Name:
- HUMAN PF-4
- Synonyms
- PLATELET FACTOR 4;PF-4;CXCL4;SCYB4;Ironplact;HUMAN PF-4;PF-4, HUMAN;HUMAN CXCL4;Oncostatin A;HUMAN IROPLACT
- CBNumber:
- CB6313720
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131925
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| WGK Germany | 3 |
|---|---|
| HS Code | 3504009000 |
| Storage Class | 11 - Combustible Solids |
HUMAN PF-4 price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3142 | PF-4 (CXCL4) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 37270-94-3 | 20μG | $337 | 2026-04-30 | Buy |
| Sigma-Aldrich | SRP3142 | PF-4 (CXCL4) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 37270-94-3 | 1MG | $3910 | 2026-04-30 | Buy |
| Sigma-Aldrich | RAB0402 | Human Platelet Factor-4 / CXCL4 ELISA Kit for serum, plasma, cell culture supernatant and urine | 1KIT | $608 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SRP3231 | PF-4 from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 20 μg | $356 | 2025-07-31 | Buy | |
| Sigma-Aldrich | SRP3231 | PF-4 from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 1 mg | $1400 | 2025-07-31 | Buy |
HUMAN PF-4 Chemical Properties, Uses, Production
Uses
For research use only. Not for use in diagnostic procedures.
Human Platelet Factor-4 (PF4)/ CXCL4 (chemokine (C-X-C motif) ligand 4) ELISA Kit has been used to measure PF-4 / CXCL4 serum level in chronic myelomonocytic leukemia (CMML) patients.', 'Human Platelet Factor-4 / CXCL4 ELISA Kit has also been used in the measurement of platelet factor-4 in serum samples of prostate cancer and pseudoxanthoma elasticum patients.
General Description
Platelet factor-4 (PF-4) is a CXC chemokine that is expressed in megakaryocytes and stored in the alpha-granules of platelets. The gene encoding this protein is localized on human chromosome 4. Recombinant human PF-4 is a 7.8kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.
Biochem/physiol Actions
Platelet factor-4 (PF-4) is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. This protein associates with heparin and neutralizes it. It also neutralizes various negatively charged proteoglycans.
Description
CXCL4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 70 amino acids and having a molecular mass of 7.8 kDa.
Source
Escherichia Coli
Background
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets. Its major physiologic role appears to be neutralization of molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemokine family. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.
HUMAN PF-4 Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN PF-4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9925 | 58 |
| Shanghai Yingxin Laboratory Equipment Co., Ltd. | 021-59178156 17002132182 | 3146474380@qq.com | China | 9997 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| ACROBiosystems | 13121935750 | jiaxin.zhao@acrobiosystems.com | China | 1582 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 021-60514606 18321282235 | sale1@shybsw.net | China | 8165 | 58 |
| Shanghai Xinyu Biotechnology Co., Ltd | 13301728348 | 13301728348@163.com | China | 8000 | 58 |
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