tert-Butyl 3-acetoxyazetidine-1-carboxylate
- CAS No.
- 1215205-53-0
- Chemical Name:
- tert-Butyl 3-acetoxyazetidine-1-carboxylate
- Synonyms
- tert-Butyl 3-acetoxyazetidine-1-carboxylate;1-Azetidinecarboxylic acid, 3-(acetyloxy)-, 1,1-dimethylethyl ester
- CBNumber:
- CB63161834
- Molecular Formula:
- C10H17NO4
- Molecular Weight:
- 215.25
- MDL Number:
- MFCD24445131
- MOL File:
- 1215205-53-0.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
tert-Butyl 3-acetoxyazetidine-1-carboxylate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | B53236 | tert-Butyl 3-acetoxyazetidine-1-carboxylate 95% | 1215205-53-0 | 250mg | $15 | 2026-05-06 | Buy |
| Synthonix | B53236 | tert-Butyl 3-acetoxyazetidine-1-carboxylate 95% | 1215205-53-0 | 1g | $2456 | 2026-05-06 | Buy |
| Synthonix | B53236 | tert-Butyl 3-acetoxyazetidine-1-carboxylate 95% | 1215205-53-0 | 5g | $2790 | 2026-05-06 | Buy |
| Synthonix | B53236 | tert-Butyl 3-acetoxyazetidine-1-carboxylate 95% | 1215205-53-0 | 25g | $13950 | 2026-05-06 | Buy |
| aablocks | AA00HG7F | tert-Butyl 3-acetoxyazetidine-1-carboxylate 95% | 1215205-53-0 | 1g | $28 | 2026-05-29 | Buy |
tert-Butyl 3-acetoxyazetidine-1-carboxylate Chemical Properties, Uses, Production
Synthesis
108-24-7
141699-55-0
1215205-53-0
General procedure for the synthesis of tert-butyl 3-acetoxyazetidine-1-carboxylate from ethanoic anhydride and N-Boc-3-hydroxyazetidine: 0.27 g (1.559 mmol) of N-Boc-3-hydroxyazetidine, 0.61 g (4.677 mmol) of diisopropylethylamine and a catalytic amount of 4-dimethylaminopyridine were dissolved at 0 °C in 7 mL of dichloromethane in dichloromethane. To this solution 0.32 g (2 mmol) of acetic anhydride was slowly added, followed by stirring the reaction for 16 hours at room temperature. After completion of the reaction, the solvent was removed by vacuum distillation. The crude product was purified by column chromatography using a mixed solvent system of hexane and ethyl acetate (3:1, v/v) to give 0.33 g (98% yield) of tert-butyl 3-acetoxyazetidine-1-carboxylate. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 5.12 (1H, m), 4.23 (2H, dd), 4.12 (2H, dd), 2.09 (3H, s), 1.44 (9H, s).
References
[1] Patent: US2011/166121, 2011, A1. Location in patent: Page/Page column 56
tert-Butyl 3-acetoxyazetidine-1-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
tert-Butyl 3-acetoxyazetidine-1-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
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