Triethylene glycol dimethyl ether
- CAS No.
- 112-49-2
- Chemical Name:
- Triethylene glycol dimethyl ether
- Synonyms
- TRIGLYME;TRIETHYLENE GLYCOL DIMETHYL ETHER;2,5,8,11-TETRAOXADODECANE;1,2-BIS(2-METHOXYETHOXY)ETHANE;DIMETHYLTRIGLYCOL;glyme4;Glyme-3;riglyme;ansulether161;dimethyltrigol
- CBNumber:
- CB6326946
- Molecular Formula:
- C8H18O4
- Molecular Weight:
- 178.23
- MDL Number:
- MFCD00008504
- MOL File:
- 112-49-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Triethylene glycol dimethyl ether ReagentPlus , 99% | T59803 | 250g | $85.9 |
| Triethylene glycol dimethyl ether (stabilised) for synthesis | 8.08249 | 250ML | $54.1 |
| Triethylene glycol dimethyl ether analytical standard | 05284 | 50mg | $103 |
| Triethylene Glycol Dimethyl Ether (stabilized with BHT) >99.0%(GC) | B0496 | 25g | $26 |
| Triethylene Glycol Dimethyl Ether (stabilized with BHT) >99.0%(GC) | B0496 | 500g | $68 |
| More product size | |||
| Melting point | −45 °C(lit.) |
|---|---|
| Boiling point | 216 °C(lit.) |
| Density | 0.986 g/mL at 25 °C(lit.) |
| vapor density | >4.7 (vs air) |
| vapor pressure | 1.2 hPa (20 °C) |
| refractive index |
n |
| Flash point | 231 °F |
| storage temp. | Store below +30°C. |
| solubility | >1000g/l soluble |
| form | Liquid |
| color | APHA: ≤20 |
| PH | 7 |
| explosive limit | 0.7%(V) |
| Water Solubility | Soluble |
| Thermal Conductivity | 0.13 W/(m·K) at 25 ℃ |
| Sensitive | Hygroscopic |
| Merck | 14,9692 |
| BRN | 1700630 |
| Dielectric constant | 7.5 |
| Major Application | environmental |
| InChI | 1S/C8H18O4/c1-9-3-5-11-7-8-12-6-4-10-2/h3-8H2,1-2H3 |
| InChIKey | YFNKIDBQEZZDLK-UHFFFAOYSA-N |
| SMILES | COCCOCCOCCOC |
| LogP | -0.52 at 20℃ |
| Surface tension | 27.56mN/m at 298.15K |
| Substances of Very High Concern (SVHC) Candidate List | 1,2-bis(2-methoxyethoxy)ethane (TEGDME; triglyme) (112-49-2) |
| CAS DataBase Reference | 112-49-2(CAS DataBase Reference) |
| EWG's Food Scores | 2 |
| FDA UNII | 32YXG88KK0 |
| NIST Chemistry Reference | 2,5,8,11-Tetraoxadodecane(112-49-2) |
| EPA Substance Registry System | Triethylene glycol dimethyl ether (112-49-2) |
| UNSPSC Code | 12352112 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H319-H360Df | |||||||||
| Precautionary statements | P202-P264-P280-P305+P351+P338-P308+P313-P337+P313 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 61-19-62 | |||||||||
| Safety Statements | 53-45 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | XF0665000 | |||||||||
| F | 3 | |||||||||
| Autoignition Temperature | 375 °F | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29094990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Eye Irrit. 2 Repr. 1B |
|||||||||
| Toxicity | LD50 orally in Rabbit: 5390 mg/kg | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Triethylene glycol dimethyl ether price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T59803 | Triethylene glycol dimethyl ether ReagentPlus , 99% | 112-49-2 | 250g | $85.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.08249 | Triethylene glycol dimethyl ether (stabilised) for synthesis | 112-49-2 | 250ML | $54.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 05284 | Triethylene glycol dimethyl ether analytical standard | 112-49-2 | 50mg | $103 | 2026-04-30 | Buy |
| TCI Chemical | B0496 | Triethylene Glycol Dimethyl Ether (stabilized with BHT) >99.0%(GC) | 112-49-2 | 25g | $26 | 2026-04-30 | Buy |
| TCI Chemical | B0496 | Triethylene Glycol Dimethyl Ether (stabilized with BHT) >99.0%(GC) | 112-49-2 | 500g | $68 | 2026-04-30 | Buy |
Triethylene glycol dimethyl ether Chemical Properties,Uses,Production
Chemical Properties
Water-white liquid; mild ether odor. D 0.9862 (20/20C), refr index 1.4233 (20C), flash p 232F (111C), bp 216.0C (760mmHg), 153.6C (100 mm Hg), fp 46C. Completely soluble in water and hydrocarbons at 20C. May contain peroxides. Combustible.
Uses
Triethylene glycol dimethyl ether is used as a solvent for gases and coupling immiscible liquid. It is also used to prepare perfluoro-triethyleneglycoldimethylether.
Uses
Triethylene glycol dimethyl ether may be used as an analytical standard for the quantification of the analyte in water samples using in vitro bioassays and chemical screening technique.
Uses
Labelled Triglyme. It is used as a solvent.
Definition
ChEBI: A polyether that consists of dodecane in which the carbon atoms at positions 2, 5, 8 and 11 are replaced by oxygen atoms.
Application
Triethylene glycol dimethyl ether is a member of the glycol ether class of industrial solvents. These solvents are widely used to manufacture protective coatings such as lacquers, metal coatings, baking enamels, phenolic varnishes, epoxy resin coatings, and alkyl resins[1].
Reactivity Profile
TRIETHYLENE GLYCOL DIMETHYL ETHER forms explosive peroxides on prolonged exposure to air. Its decomposition products may be sensitive to shock. The bulk chemical is stable for 2 weeks at temperatures up to 140° F when protected from light. TRIETHYLENE GLYCOL DIMETHYL ETHER is incompatible with strong oxidizers. TRIETHYLENE GLYCOL DIMETHYL ETHER is also incompatible with strong acids. TRIETHYLENE GLYCOL DIMETHYL ETHER may react with peroxides, oxygen, nitric acid and sulfuric acid. .
Flammability and Explosibility
Non flammable
Toxicology
Triethylene glycol dimethyl ether (triEGdiME) is a widely used organic solvent. It is structurally related to several compounds that produce reproductive and developmental toxicity, including teratogenicity in laboratory animals. In the present studies, triEGdiME (0, 75, 125, 175, or 250 mg/kg/day) is administered by gavage in distilled water to timed-pregnant New Zealand white rabbits (15-25 dams/group) during major organogenesis [Gestational Days (gd) 6-19]. In the triEGdiME study, clinical signs of toxicity were minimal, and there was no increased maternal mortality. Maternal body weight and gravid uterine weight were significantly reduced at 250 mg/kg/day, whereas maternal weight gain during treatment was significant. They were depressed at doses of 175 mg/kg/day and above. Prenatal mortality was significantly increased at 250 mg triEGdiME/kg/day. TriEGdiME at doses of 175 and 250 mg/kg/day caused a significant increase in the incidence of malformed fetuses per litter. Malformations noted most frequently in fetuses of normal size included anonychia (missing toenails with no digital abnormalities), abnormally small spleen, and hydronephrosis[1].
Purification Methods
Reflux it with, and distil it from sodium hydride or LiAlH4. [Beilstein 1 IV 2401.]
Triethylene glycol dimethyl ether Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui lixing chemical co.,ltd | +86-5638152626 +86-17756305689 | gdq@lixingchem.com | China | 10 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5225 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Yunjian (Guangzhou) Import Export Trade Co., Ltd | +86-13322801610 +86-15521457061 | catherina@yunjianmaoyi.com | China | 248 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
View Lastest Price from Triethylene glycol dimethyl ether manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-15 | Triethylene glycol dimethyl ether
112-49-2
|
$5.00 | 1kg | ≥99% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2026-05-28 | TRIETHYLENE GLYCOL DIMETHYL ETHER
112-49-2
|
$10.60 | 1KG | 99% | 5000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-01-24 | 1,1-Di(2-methoxy ethoxy)ethane
112-49-2
|
200kg | 99% | 20 Ton | Yunjian (Guangzhou) Import Export Trade Co., Ltd |
-
- Triethylene glycol dimethyl ether
112-49-2
- $5.00
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- TRIETHYLENE GLYCOL DIMETHYL ETHER
112-49-2
- $10.60
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 1,1-Di(2-methoxy ethoxy)ethane
112-49-2
- $0.00
- 99%
- Yunjian (Guangzhou) Import Export Trade Co., Ltd
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