3-(1-Piperidinylmethyl)phenol
- CAS No.
- 73279-04-6
- Chemical Name:
- 3-(1-Piperidinylmethyl)phenol
- Synonyms
- Piperidinol;3-(1-Piperidinyl;BUTTPARK 99\50-17;Roxatidine Impurity 4;3-(1-Piperidinyl)Phenol;3-(Piperidinomethyl)phenol;m-(Piperidinomethyl)phenol;3-(1-Piperidylmethyl)phenol;3-(1-PIPERIDINOMETHYL)PHENOL;3-(1-PIPERIDINYLMETHYL)PHENOL
- CBNumber:
- CB6328672
- Molecular Formula:
- C12H17NO
- Molecular Weight:
- 191.27
- MDL Number:
- MFCD00800250
- MOL File:
- 73279-04-6.mol
- MSDS File:
- SDS
| Melting point | 137-138°C |
|---|---|
| Boiling point | 308.1±17.0 °C(Predicted) |
| Density | 1.097±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 9.97±0.10(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C12H17NO/c14-12-6-4-5-11(9-12)10-13-7-2-1-3-8-13/h4-6,9,14H,1-3,7-8,10H2 |
| InChIKey | ORGBERFQYFWYGX-UHFFFAOYSA-N |
| SMILES | C1(O)=CC=CC(CN2CCCCC2)=C1 |
| CAS DataBase Reference | 73279-04-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
3-(1-Piperidinylmethyl)phenol price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T311855 | 3-(1-PIPERIDINYLMETHYL)PHENOL AldrichCPR | 73279-04-6 | 5MG | $138 | 2023-06-20 | Buy |
| TCI Chemical | H1183 | 1-(3-Hydroxybenzyl)piperidine >98.0%(GC) | 73279-04-6 | 5g | $105 | 2025-07-31 | Buy |
| TCI Chemical | H1183 | 1-(3-Hydroxybenzyl)piperidine >98.0%(GC) | 73279-04-6 | 25g | $417 | 2025-07-31 | Buy |
| TRC | B448963 | 3-(Piperidin-1-ylmethyl)phenol | 73279-04-6 | 50mg | $45 | 2021-12-16 | Buy |
| TRC | B448963 | 3-(Piperidin-1-ylmethyl)phenol | 73279-04-6 | 100mg | $60 | 2021-12-16 | Buy |
3-(1-Piperidinylmethyl)phenol Chemical Properties,Uses,Production
Synthesis
110-89-4
100-83-4
73279-04-6
In a three-necked flask equipped with a stirrer, condenser tube and thermometer, add 2.4 g of m-hydroxybenzaldehyde dissolved in 40 mL of formic acid with stirring. The temperature was controlled to be below 60 °C and 4.2 g of hexahydropyridine was slowly added dropwise. After the dropwise addition was completed, the temperature was raised to 110 °C and the reaction was refluxed for 2 h (the progress of the reaction was monitored by thin layer chromatography). Upon completion of the reaction, the reaction solution was diluted with 150 mL of water and cooled to 15 °C. Decolorization was carried out by adding 0.1 g of activated carbon and filtered. The pH of the filtrate was adjusted with 12% ammonia to 8.5. allowed to stand and crystallized at 10 °C. The crystals were collected by filtration, washed with cold water and dried to give Intermediate III-1 (3-(1-piperidinylmethyl)phenol) 3.0 g as yellow crystals in 78% yield.
References
[1] Arzneimittel-Forschung/Drug Research, 1985, vol. 35, # 7, p. 1025 - 1029
[2] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 4, p. 989 - 994
[3] ChemMedChem, 2015, vol. 10, # 1, p. 83 - 93
[4] Patent: CN103626722, 2016, B. Location in patent: Paragraph 0049-0052
[5] Synthetic Communications, 1999, vol. 29, # 1, p. 15 - 20
3-(1-Piperidinylmethyl)phenol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 12872 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20906 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 | alfa10@alfachem.cn | China | 12932 | 58 |
View Lastest Price from 3-(1-Piperidinylmethyl)phenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-05-23 | 3-(1-Piperidinylmethyl)phenol
73279-04-6
|
US $1.10 / g | 1g | 99.0% Min | 100 Tons | Dideu Industries Group Limited | |
 |
2020-02-26 | 3-(1-Piperidinylmethyl)phenol
73279-04-6
|
US $0.00-0.00 / g | 5g | 99%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | 3-(1-Piperidinylmethyl)phenol
73279-04-6
|
US $1.00 / kg | 1kg | 96%-99% | as request | Career Henan Chemical Co |
-
- 3-(1-Piperidinylmethyl)phenol
73279-04-6
- US $1.10 / g
- 99.0% Min
- Dideu Industries Group Limited
-
- 3-(1-Piperidinylmethyl)phenol
73279-04-6
- US $0.00-0.00 / g
- 99%+
- Shaanxi Dideu Medichem Co. Ltd
-
- 3-(1-Piperidinylmethyl)phenol
73279-04-6
- US $1.00 / kg
- 96%-99%
- Career Henan Chemical Co
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