ChemicalBook >> CAS DataBase List >>AZD5991
AZD5991
- CAS No.
- 2143010-83-5
- Chemical Name:
- AZD5991
- Synonyms
- AZD5991;AZD5991 ，S8643;AZD-5991 Racemate;AZD 5991 Racemate,AZD5991 Racemate;22H-9,4,8-(Metheniminomethyno)-14,20:26,23-dimetheno-10H,20H-pyrazolo[4,3-l][2,15,22,18,19]benzoxadithiadiazacyclohexacosine-32-carboxylic acid, 5-chloro-2,11,12,24,27,29-hexahydro-2,3,24,33-tetramethyl-
- CBNumber:
- CB63364606
- Molecular Formula:
- C35H34ClN5O3S2
- Molecular Weight:
- 672.26
- MDL Number:
- MFCD31807622
- MOL File:
- 2143010-83-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-04-24 14:58:57
| Product description | Number | Pack Size | Price |
| AZD5991 | TKD01083 | 5mg | $1670.55 |
| AZD5991 | TKD01083 | 10mg | $2672.8 |
| AZD5991 | TKD01083 | 25mg | $5011.5 |
| AZD5991 | TKD01083 | 50mg | $8018.5 |
| AZD-5991 Racemate | CS-0077938 | 1mg | $184 |
| Boiling point | 949.6±65.0 °C(Predicted) |
|---|---|
| Density | 1.42±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| FDA UNII | E3T5XXY9HX |
AZD5991 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | TKD01083 | AZD5991 | 2143010-83-5 | 5mg | $1670.55 | 2026-06-05 | Buy |
| Biosynth | TKD01083 | AZD5991 | 2143010-83-5 | 10mg | $2672.8 | 2026-06-05 | Buy |
| Biosynth | TKD01083 | AZD5991 | 2143010-83-5 | 25mg | $5011.5 | 2026-06-05 | Buy |
| Biosynth | TKD01083 | AZD5991 | 2143010-83-5 | 50mg | $8018.5 | 2026-06-05 | Buy |
| ChemScene | CS-0077938 | AZD-5991 Racemate | 2143010-83-5 | 1mg | $184 | 2026-06-04 | Buy |
AZD5991 Chemical Properties,Uses,Production
Uses
AZD-5991 Racemate is the racemate of AZD-5991. AZD-5991 Racemate is a Mcl-1 inhibitor with an IC50 of <3 nM in FRET assay.
IC 50
Mcl-1: 3 nM (IC50)
References
[1] Tron AE, et al. Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nat Commun. 2018 Dec 17;9(1):5341. DOI:10.1038/s41467-018-07551-w
AZD5991 Preparation Products And Raw materials
Raw materials
Preparation Products
AZD5991 Suppliers
Global( 38)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +8613382787392 | sales@aeechem.com | China | 10002 | 58 |
| ChemCell Biomedicine Co.,Ltd. | 020-13556033878 2965585218 13556033878 | chemcell@hotmail.com | China | 369 | 52 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2975 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 18101056239 | 3193328036@qq.com | China | 29660 | 68 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| TOSUN PHARM | 020-66392521-118 18922260391 | 3004261881@qq.com | China | 7973 | 58 |
AZD5991
AZD-5991 Racemate
22H-9,4,8-(Metheniminomethyno)-14,20:26,23-dimetheno-10H,20H-pyrazolo[4,3-l][2,15,22,18,19]benzoxadithiadiazacyclohexacosine-32-carboxylic acid, 5-chloro-2,11,12,24,27,29-hexahydro-2,3,24,33-tetramethyl-
AZD 5991 Racemate,AZD5991 Racemate
AZD5991 ，S8643
2143010-83-5
C35H34ClN5O3S2
