1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID
- CAS No.
- 139755-99-0
- Chemical Name:
- 1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID
- Synonyms
- TIMTEC-BB SBB010494;CHEMBRDG-BB 4402460;Sildenafil Impurity 57;ASINEX-REAG BAS 02107705;Methisosildenafil Impurity 14;2-methyl-5-propyl-3-pyrazolecarboxylate;1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID;2-methyl-5-propylpyrazole-3-carboxylic acid;1-METHYL-3-PROPYL-5-PYRAZOLE CARBOXYLIC ACID;1-Methyl-3-propyl-1H-pyrazole-5-carboxylicaci
- CBNumber:
- CB6337087
- Molecular Formula:
- C8H12N2O2
- Molecular Weight:
- 168.19
- MDL Number:
- MFCD02169703
- MOL File:
- 139755-99-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Methyl-3-propyl-1H-pyrazole-5-carboxylic Acid | TRC-M320655-250MG | 250mg | $133 |
| 2-Methyl-5-propyl-2H-pyrazole-3-carboxylic acid | 032788 | 1.00g | $67 |
| 2-Methyl-5-propyl-2H-pyrazole-3-carboxylic acid | 032788 | 5.00g | $253 |
| 2-Methyl-5-propyl-2H-pyrazole-3-carboxylic acid | 032788 | 10.00g | $432 |
| 1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid 95+% | M46991 | 250mg | $90 |
| More product size | |||
| Melting point | 150-154 °C |
|---|---|
| Boiling point | 330.3±30.0 °C(Predicted) |
| Density | 1.19±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.10±0.25(Predicted) |
| color | Off-White to Pale Beige |
| CAS DataBase Reference | 139755-99-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H290-H302-H314 |
| Precautionary statements | P264b-P270-P271-P280-P304+P340-P305+P351+P338-P310-P330-P331-P363-P390-P402-P403+P233-P406b-P501c |
| Risk Statements | 20/21/22 |
| Safety Statements | 3/9-24/25-36/37 |
| HazardClass | IRRITANT |
| HS Code | 29331990 |
1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-M320655-250MG | 1-Methyl-3-propyl-1H-pyrazole-5-carboxylic Acid | 139755-99-0 | 250mg | $133 | 2026-06-03 | Buy |
| Matrix Scientific | 032788 | 2-Methyl-5-propyl-2H-pyrazole-3-carboxylic acid | 139755-99-0 | 1.00g | $67 | 2026-05-18 | Buy |
| Matrix Scientific | 032788 | 2-Methyl-5-propyl-2H-pyrazole-3-carboxylic acid | 139755-99-0 | 5.00g | $253 | 2026-05-18 | Buy |
| Matrix Scientific | 032788 | 2-Methyl-5-propyl-2H-pyrazole-3-carboxylic acid | 139755-99-0 | 10.00g | $432 | 2026-05-18 | Buy |
| Synthonix | M46991 | 1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid 95+% | 139755-99-0 | 250mg | $90 | 2026-05-06 | Buy |
1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID Chemical Properties,Uses,Production
Chemical Properties
White solid
Uses
Intermediate in the production of Sildenafil and respective analogs.
Synthesis
133261-07-1
139755-99-0
Preparation of Intermediate I-04a: Ethyl 1-methyl-3-n-propyl-pyrazole-5-carboxylate (11 g, 56.12 mmol) was dissolved in 6 M hydrochloric acid solution (121 mL) and heated to 100°C for overnight reaction. Upon completion of the reaction, the mixture was concentrated under vacuum and subsequently extracted with ethyl acetate (EA) and the organic layer was washed with water. Finally, the organic layer was concentrated in vacuum to afford the target product 1-methyl-3-propyl-1H-pyrazole-5-carboxylic acid (I-04a) (9.4 g, 98% yield).ESI-MS (M + 1): 169; calculated value C8H12N2O2: 168.1.
References
[1] Patent: WO2014/131855, 2014, A1. Location in patent: Page/Page column 80
[2] Patent: WO2016/20307, 2016, A1. Location in patent: Page/Page column 50
[3] Patent: US2008/194529, 2008, A1. Location in patent: Page/Page column 56-57
[4] Patent: WO2015/114647, 2015, A1. Location in patent: Page/Page column 46; 47
[5] Patent: US5250534, 1993, A
1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Hunan Jibang Biological Technology Co., LTD | +8613776644403 | sales02@kingboomtech.com | China | 1804 | 58 |
View Lastest Price from 1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID
139755-99-0
|
$1.00 | 1kg | 98% | 100KG | Career Henan Chemical Co |
-
- 1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID
139755-99-0
- $1.00
- 98%
- Career Henan Chemical Co
139755-99-0(1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID)Related Search:
1of4
