CL2-SN38
- CAS No.
- 1036969-20-6
- Chemical Name:
- CL2-SN38
- Synonyms
- CS-2807;CL2-SN38;CL2-SN-38(DCA);L-Lysinamide, N-[32-[4-[[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]methyl]-1H-1,2,3-triazol-1-yl]-1,5-dioxo-3,9,12,15,18,21,24,27,30-nonaoxa-6-azadotriacont-1-yl]-L-phenylalanyl-N-[4-[[[[[(4S)-4,11-diethyl-3,4,12,14-tetrahydro-9-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,...
- CBNumber:
- CB63379932
- Molecular Formula:
- C82H106N12O23
- Molecular Weight:
- 1627.81
- MDL Number:
- MFCD32201108
- MOL File:
- 1036969-20-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| CL2-SN-38 (dichloroacetic acid salt) ≥90% | 28215 | 1mg | $36 |
| CL2-SN-38 (dichloroacetic acid salt) ≥90% | 28215 | 5mg | $153 |
| CL2-SN-38 (dichloroacetic acid salt) ≥90% | 28215 | 10mg | $268 |
| CL2-SN-38 (dichloroacetic acid salt) ≥90% | 28215 | 25mg | $587 |
| CL2-SN-38 98.68% | CS-0102763 | 25mg | $580 |
CL2-SN38 price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28215 | CL2-SN-38 (dichloroacetic acid salt) ≥90% | 1036969-20-6 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 28215 | CL2-SN-38 (dichloroacetic acid salt) ≥90% | 1036969-20-6 | 5mg | $153 | 2026-04-30 | Buy |
| Cayman Chemical | 28215 | CL2-SN-38 (dichloroacetic acid salt) ≥90% | 1036969-20-6 | 10mg | $268 | 2026-04-30 | Buy |
| Cayman Chemical | 28215 | CL2-SN-38 (dichloroacetic acid salt) ≥90% | 1036969-20-6 | 25mg | $587 | 2026-04-30 | Buy |
| ChemScene | CS-0102763 | CL2-SN-38 98.68% | 1036969-20-6 | 25mg | $580 | 2021-12-16 | Buy |
CL2-SN38 Chemical Properties,Uses,Production
Uses
CL2-SN-38 is a cleavable linker-based agent-Linker conjugate, it can conjugate with the anti-Trop-2-humanized antibody hRS7. CL2-SN-38 can be used for the reasearch of cancer[1].
IC 50
Camptothecins
References
[1] Cardillo TM, et al. Humanized anti-Trop-2 IgG-SN-38 conjugate for effective treatment of diverse epithelial cancers: preclinical studies in human cancer xenograft models and monkeys. Clin Cancer Res. 2011 May 15;17(10):3157-69. DOI:10.1158/1078-0432.CCR-10-2939
[2] SUNG-JU MOON. Antibody Conjugates of 7-Ethyl-10-hydroxycamptothecin (SN-38) for Targeted Cancer Chemotherapy[J]. Journal of Medicinal Chemistry, 2008, 51 21: 6916-6926. DOI: 10.1021/jm800719t
CL2-SN38 Preparation Products And Raw materials
Raw materials
Preparation Products
CL2-SN38 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| ChemExpress | +86-19370970350 +86-021-58950125 | info@chemexpress.com | China | 788 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +8613382787392 | sales@aeechem.com | China | 10000 | 58 |
| Henan Rane Chemical Co., Ltd. | +8618738066252 | info@ranechem.com | China | 2999 | 58 |
| Shanghai Chaolan Chemical Technology Center | 021-QQ：65489617 15618227136 | Sales@ATKchemical.com | China | 9550 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| Cool Pharm, Ltd | 021-58581007 18019463053 | sales@coolpharm.com | China | 10000 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
