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4-nitrobenzaldehyde thiosemicarbazone

CAS No.
180864-33-9
Chemical Name:
4-nitrobenzaldehyde thiosemicarbazone
Synonyms
Tyrosinase-IN-2;Tyrosinase-IN-2, 10 mM in DMSO;(E)-2-(4-Nitrobenzylidene)hydrazine-1-carbothioamide;Hydrazinecarbothioamide, 2-[(4-nitrophenyl)methylene]-, (2E)-
CBNumber:
CB63600177
Molecular Formula:
C8H8N4O2S
Molecular Weight:
224.24
MDL Number:
MOL File:
180864-33-9.mol
Last updated:2025-09-17 14:35:14

4-nitrobenzaldehyde thiosemicarbazone Properties

Melting point 234-235 °C (decomp)
Boiling point 405.6±47.0 °C(Predicted)
Density 1.46±0.1 g/cm3(Predicted)
pka 11.09±0.70(Predicted)
form Solid
color Light yellow to yellow

4-nitrobenzaldehyde thiosemicarbazone Chemical Properties,Uses,Production

Uses

Tyrosinase-IN-2 (compound 67) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-2 has the potential for the research of skin whitening agents and food preservatives[1].

References

[1] Li J, et al. Recent advances in the design and discovery of synthetic tyrosinase inhibitors. Eur J Med Chem. 2021;224:113744. DOI:10.1016/j.ejmech.2021.113744

4-nitrobenzaldehyde thiosemicarbazone Preparation Products And Raw materials

Raw materials

Preparation Products

4-nitrobenzaldehyde thiosemicarbazone Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32432 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4669 55
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 6772 55
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2957 58
Shanghai Chaolan Chemical Technology Center 021-QQ:65489617 15618227136 Sales@ATKchemical.com China 9848 58
Shanghai Yu Ben Biotechnology Co., Ltd. 15502154572 yuben012@sina.com China 491 58
Amel Pharmatech Corporation 027-888-4366503 sales@amelpharmatech.com China 5000 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62320 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24989 58

View Lastest Price from 4-nitrobenzaldehyde thiosemicarbazone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tyrosinase-IN-2 pictures 2025-09-17 Tyrosinase-IN-2
180864-33-9
US $40.00-137.00 / mg 99.78% 10g TargetMol Chemicals Inc.
  • Tyrosinase-IN-2 pictures
  • Tyrosinase-IN-2
    180864-33-9
  • US $40.00-137.00 / mg
  • 99.78%
  • TargetMol Chemicals Inc.

4-nitrobenzaldehyde thiosemicarbazone Spectrum

Tyrosinase-IN-2 Hydrazinecarbothioamide, 2-[(4-nitrophenyl)methylene]-, (2E)- (E)-2-(4-Nitrobenzylidene)hydrazine-1-carbothioamide Tyrosinase-IN-2, 10 mM in DMSO 180864-33-9