TCID
- CAS No.
- 30675-13-9
- Chemical Name:
- TCID
- Synonyms
- TCID;TCID USP/EP/BP;UCH-L3 Inhibitor;TCID >=98% (HPLC);TCID, 10 mM in DMSO;4,5,6,7-TETRACHLOROINDAN-1,3-DIONE;4,5,6,7-TETRACHLOROINDANE-1,3-DIONE;4,5,6,7-Tetrachloro-1,3-indanedione;4,5,6,7-Tetrachloroindane-1,3-dione 95+%;4,5,6,7-TETRACHLORO-1H-INDENE-1,3(2H)-DIONE
- CBNumber:
- CB6366908
- Molecular Formula:
- C9H2Cl4O2
- Molecular Weight:
- 283.92
- MDL Number:
- MFCD00239209
- MOL File:
- 30675-13-9.mol
| Product description | Number | Pack Size | Price |
| TCID ≥98% (HPLC) | SML1402 | 5mg | $78.6 |
| TCID ≥95% | 16353 | 5mg | $73 |
| TCID ≥95% | 16353 | 10mg | $116 |
| TCID ≥95% | 16353 | 25mg | $263 |
| TCID ≥99%(HPLC) | 5179 | 50 | $540 |
| More product size | |||
| Melting point | 218-220 |
|---|---|
| Boiling point | 448.1±45.0 °C(Predicted) |
| Density | 1.782±0.06 g/cm3(Predicted) |
| storage temp. | +2C to +8C |
| solubility | Soluble in DMSO (up to 25 mg/ml), |
| pka | 8.62±0.20(Predicted) |
| form | Orange solid |
| color | White |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| InChI | 1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2 |
| InChIKey | IDLAOWFFKWRNHB-UHFFFAOYSA-N |
| SMILES | O=C1CC(C2=C(Cl)C(Cl)=C(Cl)C(Cl)=C21)=O |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| WGK Germany | WGK 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
TCID price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1402 | TCID ≥98% (HPLC) | 30675-13-9 | 5mg | $78.6 | 2025-07-31 | Buy |
| Cayman Chemical | 16353 | TCID ≥95% | 30675-13-9 | 5mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 16353 | TCID ≥95% | 30675-13-9 | 10mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 16353 | TCID ≥95% | 30675-13-9 | 25mg | $263 | 2024-03-01 | Buy |
| Tocris | 5179 | TCID ≥99%(HPLC) | 30675-13-9 | 50 | $540 | 2021-12-16 | Buy |
TCID Chemical Properties,Uses,Production
Description
TCID (30675-13-9) inhibits ubiquitin C-terminal hydrolase L3 (UCH-L3). IC50=0.6 μM, 125-fold selective over UCH-L1, IC50=75 μM. Cell permeable.
Uses
TCID is a small molecule inhibitor of DNA polymerase λ.
storage
Store at -20°C
References
[1] KERRY ROUTENBERG LOVE. Mechanisms, biology and inhibitors of deubiquitinating enzymes[J]. Nature chemical biology, 2007, 3 11: 697-705. DOI:10.1038/nchembio.2007.43
[2] NAMDORI R. MTANGO. Essential role of ubiquitin C-terminal hydrolases UCHL1 and UCHL3 in mammalian oocyte maturation[J]. Journal of Cellular Physiology, 2011, 227 5: 2022-2029. DOI:10.1002/jcp.22931
TCID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 19282 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39042 | 58 |
