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2-Amino-3-fluorobenzoic acid

2-Amino-3-fluorobenzoic acid structure

CAS No.: 825-22-9

Chemical Name:: 2-Amino-3-fluorobenzoic acid

Synonyms: Diaphonic acid;BUTTPARK 22\01-93;uorobenzenecarboxyL;2-AMino-3-fluorobenz;2-AMINO-3-FLUOROBENZOIC;3-FLUOROANTHRANILIC ACID;3-FluoroanthranilicAcid>2-Amino-3-fluorobenzoicAci;2-AMINO-3-FLUOROBENZOIC ACID;2-Amino-3-Fluoride Benzoic Acids

CBNumber:: CB6368755

Molecular Formula:: C7H6FNO2

Molecular Weight:: 155.13

MDL Number:: MFCD01569395

MOL File:: 825-22-9.mol

MSDS File:: SDS

Last updated:2025-08-13 14:25:36

Product description	Number	Pack Size	Price
3-Fluoroanthranilic Acid >98.0%(T)	F0570	1g	$27
3-Fluoroanthranilic Acid >98.0%(T)	F0570	5g	$107
2-Amino-3-fluorobenzoicAcid	A634628	250mg	$45
2-Amino-3-fluorobenzoic acid 98%	008762	25g	$58
2-Amino-3-fluorobenzoicacid	L162	1g	$64
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2-Amino-3-fluorobenzoic acid Properties

Melting point	171-172°C
Boiling point	294.4±25.0 °C(Predicted)
Density	1.430±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	4.60±0.10(Predicted)
form	powder to crystal
color	White to Light yellow to Light orange
InChI	InChI=1S/C7H6FNO2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,9H2,(H,10,11)
InChIKey	KUHAYJJXXGBYBW-UHFFFAOYSA-N
SMILES	C(O)(=O)C1=CC=CC(F)=C1N
CAS DataBase Reference	825-22-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-22

Safety Statements

26-36/37/39-24/25

HazardClass

IRRITANT

HS Code

29223990

NFPA 704

	1
2		0

2-Amino-3-fluorobenzoic acid price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	F0570	3-Fluoroanthranilic Acid >98.0%(T)	825-22-9	1g	$27	2025-07-31	Buy
TCI Chemical	F0570	3-Fluoroanthranilic Acid >98.0%(T)	825-22-9	5g	$107	2025-07-31	Buy
TRC	A634628	2-Amino-3-fluorobenzoicAcid	825-22-9	250mg	$45	2021-12-16	Buy
Matrix Scientific	008762	2-Amino-3-fluorobenzoic acid 98%	825-22-9	25g	$58	2021-12-16	Buy
AK Scientific	L162	2-Amino-3-fluorobenzoicacid	825-22-9	1g	$64	2021-12-16	Buy

Product number	Packaging	Price	Buy
F0570	1g	$27	Buy
F0570	5g	$107	Buy
A634628	250mg	$45	Buy
008762	25g	$58	Buy
L162	1g	$64	Buy

2-Amino-3-fluorobenzoic acid Chemical Properties,Uses,Production

Application

2-Amino-3-fluorobenzoic acid is a carboxylic acid derivative and can be used as a pharmaceutical intermediate.

Chemical Properties

white to light yellow crystal powder

Synthesis

317-20-4

825-22-9

7-Fluoro-1H-indole-2,3-dione (13.0 g, 78.7 mmol) was used as raw material, which was dissolved in 10N sodium hydroxide solution (125 mL), heated to 70°C and stirred for 1 hour. At the same temperature, 30% hydrogen peroxide solution (25 mL) was added slowly and dropwise over 20 minutes and the reaction continued to be stirred at 70 °C for 1 hour. Upon completion of the reaction, the reaction solution was cooled in an ice bath and concentrated. Subsequently, hydrochloric acid was slowly added to adjust the pH of the solution to 4. The organic phase was extracted with ethyl acetate, and the extract was washed with saturated brine and dried with anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure to give the crude product. The crystals were collected by filtration to finally obtain 2-amino-3-fluorobenzoic acid (7.15 g, 59% yield). The NMR hydrogen spectrum (CDCl3) data were as follows: δ 6.00 (2H, broad single peak), 6.60 (1H, double-triple peak, J = 5.2 Hz, 8.0 Hz), 7.16 (1H, multiple peaks, J = 1.4 Hz, 8.0 Hz, 11.2 Hz), 7.72 (1H, triple-double peaks, J = 1.4 Hz, 8.0 Hz), and one additional hydrogen signal was masked.

References

[1] Organic Syntheses, 2002, vol. 79, p. 196 - 196
[2] Patent: US2003/187014, 2003, A1
[3] Proceedings of the Royal Society of London, Series B: Biological Sciences, 1958, vol. 148, p. 481,488
[4] Journal of Heterocyclic Chemistry, 1990, vol. 27, # 7, p. 2151 - 2163
[5] European Journal of Medicinal Chemistry, 1994, vol. 29, # 10, p. 743 - 751

2-Amino-3-fluorobenzoic acid Preparation Products And Raw materials

Raw materials

8-FLUORO-2,3-DIHYDROQUINOLIN-4-ONE 8-Fluoroquinolin-2,4-dione 7-Fluoroisatin Sodium hydroxide Hydrochloric acid

Hydrogen peroxide

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Preparation Products

2-Bromo-3-fluoroaniline 2-Bromo-3-fluorobenzoic acid 2-aMino-3-fluorobenzaldehyde 2-AMINO-5-BROMO-3-FLUOROBENZOIC ACID 8-fluoro-2-methyl-4H-benzo[d][1,3]oxazin-4-one

Benzenemethanol, 2-amino-3-fluoro- (9CI) 2-AMINO-3-FLUORO-N-METHYL-BENZAMIDE

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2-Amino-3-fluorobenzoic acid Suppliers

Global( 397)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hefei Lbao Physical & Chemical Science Co.,Ltd	+1-5184799099	lbaochemicals@gmail.com	China	619	58
Hubei Deli Pharmaceutical Technology Co., Ltd.	+8613372285931	dl@delipharm.com	China	97	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8754	58
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	1026@dideu.com	China	8880	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21602	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60

Supplier	Advantage
Hefei Lbao Physical & Chemical Science Co.,Ltd	58
Hubei Deli Pharmaceutical Technology Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Shaanxi Didu New Materials Co. Ltd	58
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60

View Lastest Price from 2-Amino-3-fluorobenzoic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-01-08	2-amino-3-fluorobenzoic acid 825-22-9	US $0.00 / kg	1kg	98%	Customise	Hefei Lbao Physical & Chemical Science Co.,Ltd
2026-01-05	2-Amino-3-fluorobenzoic acid 825-22-9	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2026-01-05	2-Amino-3-fluorobenzoic acid 825-22-9	US $0.10 / KG	0.1KG	98%	200TONS	Shaanxi Dideu Medichem Co. Ltd

2-amino-3-fluorobenzoic acid
825-22-9
US $0.00 / kg
98%
Hefei Lbao Physical & Chemical Science Co.,Ltd

2-Amino-3-fluorobenzoic acid
825-22-9
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-Amino-3-fluorobenzoic acid
825-22-9
US $0.10 / KG
98%
Shaanxi Dideu Medichem Co. Ltd

2-Amino-3-fluorobenzoic acid Spectrum

2-Amino-3-fluorobenzoic acid(825-22-9)MS 2-Amino-3-fluorobenzoic acid(825-22-9)¹HNMR 2-Amino-3-fluorobenzoic acid(825-22-9)IR1

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BUTTPARK 22\01-93 2-AMINO-3-FLUOROBENZENECARBOXYLIC ACID 2-AMINO-3-FLUOROBENZOIC ACID 3-FLUOROANTHRANILIC ACID 2-AMINO-3-FLUOROBENZOIC 2-Amino-3-Fluoride Benzoic Acids Benzoic acid, 2-amino-3-fluoro- 3-Fluoroanthranilic acid, 2-Carboxy-6-fluoroaniline Diaphonic acid 2-AMino-3-fluorobenz 3-FluoroanthranilicAcid> uorobenzenecarboxyL 2-Amino-3-fluorobenzoicAci 825-22-9 825-22-5 Fluorin-contained Benzoic acid series Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Fluorine series