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N-Formyl-L-leucine

N-Formyl-L-leucine structure

CAS No.: 6113-61-7

Chemical Name:: N-Formyl-L-leucine

Synonyms: FORMYL-L-LEUCINE;NSC 334321;FOR-LEU-OH;For-L-Leu-OH;N-ForMyl-Leu-OH;N-Formylleucine;FORMYL-L-ALANINE;N-Formyl-L-leucin;N-Formyl-S-leucine;N-Formyl-L-leucine

CBNumber:: CB6399029

Molecular Formula:: C7H13NO3

Molecular Weight:: 159.18

MDL Number:: MFCD00055861

MOL File:: 6113-61-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:54:14

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N-Formyl-L-leucine Properties

Melting point	142 °C
Boiling point	284.67°C (rough estimate)
Density	1.2013 (rough estimate)
refractive index	-39.5 ° (C=1, H2O)
storage temp.	-20°C
solubility	Ethanol (Sparingly), Methanol (Slightly)
form	powder
pka	3.51±0.21(Predicted)
color	white
Water Solubility	29.45g/L(temperature not stated)
Major Application	peptide synthesis
InChI	InChI=1S/C7H13NO3/c1-5(2)3-6(7(10)11)8-4-9/h4-6H,3H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1
InChIKey	HFBHOAHFRNLZGN-LURJTMIESA-N
SMILES	C(O)(=O)[C@H](CC(C)C)NC=O
CAS DataBase Reference	6113-61-7(CAS DataBase Reference)
FDA UNII	5THA63Y4FF
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

WGK Germany

HazardClass

IRRITANT

HS Code

2924297099

Storage Class

11 - Combustible Solids

REACH Registrations

Active

NFPA 704

	1
2		0

N-Formyl-L-leucine price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	759945	N-Formyl-Leu-OH 90%	6113-61-7	1g	$60	2023-01-07	Buy
TCI Chemical	F0131	N-Formyl-L-leucine	6113-61-7	1g	$21	2026-04-30	Buy
TCI Chemical	F0131	N-Formyl-L-leucine	6113-61-7	5g	$63	2026-04-30	Buy
Usbiological	276501	N-Formyl-L-leucine	6113-61-7	500mg	$425	2026-06-03	Buy
Usbiological	276501	N-Formyl-L-leucine	6113-61-7	1g	$628	2026-06-03	Buy

Product number	Packaging	Price	Buy
759945	1g	$60	Buy
F0131	1g	$21	Buy
F0131	5g	$63	Buy
276501	500mg	$425	Buy
276501	1g	$628	Buy

N-Formyl-L-leucine Chemical Properties, Uses, Production

Chemical Properties

White Solid

Uses

A synthetic substrate of the lipase inhibitor lipstatin.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

64-18-6

760-84-9

5338-45-4

General procedure: L-leucine hydrochloride (1 eq.), formic acid (5 eq.), sodium bicarbonate (10 eq.) and glycerol ketone-oxide 1 (2 eq.) were dissolved in H2O (0.2-0.3 M), followed by the addition of EDCI (2 eq.). The reaction mixture was stirred for 3 h. Upon completion of the reaction, it was quenched with 1% HCl aqueous solution. The aqueous phase was extracted with EtOAc (or CHCl3, or CHCl3-MeOH (10/1). The organic extracts were combined and dried with Na2SO4, followed by vacuum evaporation of the solvent. Purification by silica gel chromatography (or Sephadex LH20) afforded N-formyl-DL-leucine (see Table 1 for yields). Similarly, the N-formylation reaction was carried out using oxide 1 in DMF-H2O (9/1).

References

[1] Tetrahedron Letters, 2013, vol. 54, # 16, p. 2077 - 2081

N-Formyl-L-leucine Preparation Products And Raw materials

Raw materials

Formic acid L-Leucine L-Leucine hydrochloride n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Sodium bicarbonate

Preparation Products

N-Formyl-L-leucine Suppliers

Global Suppliers ( 224)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	45000	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Shandong Xiya Chemical Co., Ltd	13355009207 13355009207	3007715519@qq.com	China	18722	57
Syntechem Co.,Ltd		info@syntechem.com	China	12973	57

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Shanghai Longsheng chemical Co.,Ltd.	59
Chemsky（shanghai）International Co.,Ltd.	50
Shandong Xiya Chemical Co., Ltd	57
Syntechem Co.,Ltd	57

View Latest Price from N-Formyl-L-leucine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-30	N-FORMYL-L-LEUCINE 6113-61-7		1KG	98	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-05-23	N-FORMYL-L-LEUCINE 6113-61-7	$10.00	1kg	99%	20 ton	Hebei Zhuanglai Chemical Trading Co Ltd
2025-03-21	N-FORMYL-L-LEUCINE 6113-61-7		1KG	98%	1000KGS	Zhengzhou Anbu Chem Co.,Ltd

N-FORMYL-L-LEUCINE
6113-61-7
98
Shaanxi Dideu New Materials Co. Ltd

N-FORMYL-L-LEUCINE
6113-61-7
$10.00
99%
Hebei Zhuanglai Chemical Trading Co Ltd

N-FORMYL-L-LEUCINE
6113-61-7
$0.00
98%
Zhengzhou Anbu Chem Co.,Ltd

N-Formyl-L-leucine Spectrum

N-FORMYL-L-LEUCINE(6113-61-7)MS N-FORMYL-L-LEUCINE(6113-61-7)¹HNMR N-FORMYL-L-LEUCINE(6113-61-7)IR1 N-FORMYL-L-LEUCINE(6113-61-7)IR2

6113-61-7 (N-Formyl-L-leucine) Related Search:

[2R-[1(S*),2R*,3S*]]- N-Formyl-L-Leucine 1-[3-Carboxy-2-hydroxynonyl]dodecyl Ester,N-Formyl-L-leucine (1S)-1-[(2S,3S)-3-carboxy-2-hydroxynonyl]dodecyl Ester Orlistat Impurity 23 N-ForMyl- (2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic Acid (Orlistat Impurity) [2S-[2α(R*),3β]]-N-ForMyl-

Isopentyl (2R)-Orlistat Tetradecyl Ester Orlistat Tetradecyl Ester N-ForMyl-L-leucine [S-(E)]-1-(2-Nonenyl)dodecyl Ester (S,S,R,S)-Orlistat Orlistat Impurity 32

AHLBNYSZXLDEJQ-FICKONGGSA-N (3S,4S)-3-Hexyl-4-[(S)-2-hydroxytridecyl]-2-oxetanone AHLBNYSZXLDEJQ-HDVRVJOHSA-N Orlistat Impurity 31 Lipstatin

(2S,3S,5S)-2-Hexyl-3,5-dihydroxyhexadecanoic Acid Orlistat Dimer Impurity Diisopropyl azodicarboxylate

1of4

N-ALPHA-FORMYL-L-LEUCINE FOR-LEU-OH FORMYL-L-ALANINE N-Formylleucine N-Formyl-S-leucine NSC 334321 N-FORMYL-L-LEUCINE 99+% N-Formyl-L-leucin (2S)-2-formamido-4-methylpentanoic acid N-ForMyl-Leu-OH Orlistat ForMyl IMpurity (2S)-2-(Formylamino)-4-methylpentanoic acid (S)-2-(Formylamino)-4-methylpentanoic acid 2-formamido-4-methylpentanoic acid 2-formamido-4-methyl-pentanoic acid 2-formamido-4-methyl-valeric acid N-ForMyl-L-leucine, tech. 90% N-Formyl-Leu-OH 90% For-L-Leu-OH (S)-2-forMaMido-4-Methylpentanoic acid L-Leucine, N-forMyl- N-Formyl-L-leucine（N-Formyl-Leu-OH） Orlistat Impurity 24（N-Formyl-L-leucine） N-FORMYL-L-LEUCINE USP/EP/BP N-α-Formyl-L-leucine Orlistat Impurity 46 N-Formyl-Leu-OH (S)-2-carboxamideyl-4-methylpentanoic acid FORMYL-L-LEUCINE N-Formyl-L-leucine 6113-61-7 Amino Acids and Peptides Biochemicals and Reagents BioChemical Modified Amino Acids A - H A - H Amino Acids Modified Amino Acids Amino Acids 13C, 2H, 15N Amino Acids & Derivatives Chiral Reagents AMINOACIDS DERIVATIVES