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Cyclohexane-1,3-dicarboxylic acid dimethyl ester

CAS No.
62638-06-6
Chemical Name:
Cyclohexane-1,3-dicarboxylic acid dimethyl ester
Synonyms
diMethyl cyclohexane-1,3-dicarboxylate;Dimethyl 1,3-cyclohexane dicarboxylate;Dimethyl cyclohexane-1,3-dixarboxylate;1,3-dimethyl cyclohexane-1,3-dicarboxylate;Cyclohexane-1,3-dicarboxylic acid dimethyl ester;1,3-Cyclohexanedicarboxylic acid, 1,3-dimethyl ester
CBNumber:
CB6403544
Molecular Formula:
C10H16O4
Molecular Weight:
200.23
MDL Number:
MFCD07779254
MOL File:
62638-06-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:14

Cyclohexane-1,3-dicarboxylic acid dimethyl ester Properties

Boiling point 258.1±15.0℃ (760 Torr)
Density 1.102±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 1.4592 (589.3 nm 18℃)
Flash point 120.7±18.8℃
storage temp. Sealed in dry,Room Temperature
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

Cyclohexane-1,3-dicarboxylic acid dimethyl ester price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00ECZ0 dimethyl cyclohexane-1,3-dicarboxylate 95% 62638-06-6 100mg $8 2026-05-28 Buy
aablocks AA00ECZ0 dimethyl cyclohexane-1,3-dicarboxylate 95% 62638-06-6 250mg $10 2026-05-28 Buy
aablocks AA00ECZ0 dimethyl cyclohexane-1,3-dicarboxylate 95% 62638-06-6 1g $12 2026-05-28 Buy
aablocks AA00ECZ0 dimethyl cyclohexane-1,3-dicarboxylate 95% 62638-06-6 5g $45 2026-05-28 Buy
aablocks AA00ECZ0 dimethyl cyclohexane-1,3-dicarboxylate 95% 62638-06-6 10g $80 2026-05-28 Buy
Product number Packaging Price Buy
AA00ECZ0 100mg $8 Buy
AA00ECZ0 250mg $10 Buy
AA00ECZ0 1g $12 Buy
AA00ECZ0 5g $45 Buy
AA00ECZ0 10g $80 Buy

Cyclohexane-1,3-dicarboxylic acid dimethyl ester Chemical Properties,Uses,Production

Application

Dimethyl 1,3-cyclohexanoate can be used as a pharmaceutical synthesis intermediate and an organic synthesis intermediate, mainly in laboratory research and development processes and chemical and pharmaceutical synthesis processes.

Synthesis

Methanol

67-56-1

1,3-Cyclohexanedicarboxylic acid

3971-31-1

CYCLOHEXANE-1,3-DICARBOXYLIC ACID DIMETHYL ESTER

62638-06-6

1. cyclohexane-1,3-dicarboxylic acid (10.32 g, 60 mmol) was dissolved in methanol (130 mL). 2. Concentrated sulfuric acid (2.5 mL) was added as a catalyst and the reaction mixture was heated to reflux and stirred for 16 hours. 3. Upon completion of the reaction, the reaction mixture was concentrated under reduced pressure to remove most of the methanol. 4. The residue was adjusted to pH 7 with saturated aqueous sodium bicarbonate. 5. The aqueous phase was extracted with ethyl acetate (200 mL × 3) and the organic layers were combined. 6. 6. The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give dimethyl 1,3-cyclohexanedioate as a colorless oil (12 g, 100% yield). 7. The product was analyzed by 1H NMR. 7. The product was characterized by 1H NMR (400 MHz, DMSO-d6) and mass spectrometry (ESI): 1H NMR δ 3.61 (s, 6H), 2.69-1.13 (m, 10H); MS (ESI) m/e [M + 1] 201.1.

References

[1] Patent: WO2016/161960, 2016, A1. Location in patent: Paragraph 0542
[2] Acta Crystallographica Section C: Crystal Structure Communications, 2013, vol. 69, # 7, p. 727 - 729
[3] Patent: WO2012/88365, 2012, A1. Location in patent: Page/Page column 24
[4] Patent: WO2013/40535, 2013, A2. Location in patent: Page/Page column 23
[5] Patent: WO2016/106623, 2016, A1. Location in patent: Page/Page column 122

Cyclohexane-1,3-dicarboxylic acid dimethyl ester Preparation Products And Raw materials

Global( 67)Suppliers
Supplier Tel Email Country ProdList Advantage
skychemical Co.Ltd 021-20958197 20965099 sales@skychemical.com China 1182 57
YangZhou Ruihong Biotech Co., Ltd. 0514-015380367604 15380367604 sales@ruibobiotech.com China 509 55
Aloespharm Co., Ltd. 021-20960837 market@aloespharm.com China 1299 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9781 50
skychemical Co.Ltd 021-20960837,QQ1332204249 sales@skychemical.com China 3338 55
Shanghai Qiao Chemical Science Co., Ltd 021-58892003 info@qiaochem.com China 6065 65
Taizhou Elitechemie MediPharma Technology Co., Ltd. 523-86810021 18921709486 gwli@elitechemie.com China 500 65
Changzhou Hopschain Chemical Co.,Ltd. 85528066 13775048983 sales@hopschem.com China 31548 55
Hangzhou Molcore Biopharmatech Co.,Ltd 400-711-5280 86-571-81025280 sales@molcore.com China 9957 58

View Lastest Price from Cyclohexane-1,3-dicarboxylic acid dimethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dimethyl cyclohexane-1,3-dixarboxylate pictures 2026-09-09 Dimethyl cyclohexane-1,3-dixarboxylate
62638-06-6
100gm 97% 100kgs Shanghai Yongzeng Technology Co.,Ltd

Cyclohexane-1,3-dicarboxylic acid dimethyl ester Spectrum

Dimethyl 1,3-cyclohexane dicarboxylate 1,3-dimethyl cyclohexane-1,3-dicarboxylate 1,3-Cyclohexanedicarboxylic acid, 1,3-dimethyl ester Dimethyl cyclohexane-1,3-dixarboxylate diMethyl cyclohexane-1,3-dicarboxylate Cyclohexane-1,3-dicarboxylic acid dimethyl ester 62638-06-6