2-Bromo-3-fluorobenzoic acid
- CAS No.
- 132715-69-6
- Chemical Name:
- 2-Bromo-3-fluorobenzoic acid
- Synonyms
- EOS-61551;BUTTPARK 22\01-97;2-Bromo-3-fluorobenzoic;2-BROMO-3-FLUOROBENZOIC ACID;3-Fluoro-2-Bromo Benzoic Acid;Benzoic acid, 2-broMo-3-fluoro-;2-Bromo-3-fluorobenzoic acid 98%;2-Bromo-3-fluorobenzoic Acid >2-Bromine-3-Fluoride Benzoic Acids;3-Fluoro-2-Bromo Benzoic Acid 2-Bromo-3-Fluorobenzoic Acid
- CBNumber:
- CB6417095
- Molecular Formula:
- C7H4BrFO2
- Molecular Weight:
- 219.01
- MDL Number:
- MFCD01569398
- MOL File:
- 132715-69-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Bromo-3-fluorobenzoic Acid >96.0%(GC)(T) | B3722 | 1g | $64 |
| 2-Bromo-3-fluorobenzoic Acid >96.0%(GC)(T) | B3722 | 5g | $198 |
| 2-Bromo-3-fluorobenzoic acid | 415763 | 100mg | $305 |
| 2-Bromo-3-fluorobenzoic acid | FB38482 | 25g | $200 |
| 2-Bromo-3-fluorobenzoic acid | FB38482 | 50g | $300 |
| More product size | |||
| Melting point | 158-160°C |
|---|---|
| Boiling point | 292.7±25.0 °C(Predicted) |
| Density | 1.789±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 2.51±0.10(Predicted) |
| color | White to Light yellow to Light orange |
| InChI | InChI=1S/C7H4BrFO2/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3H,(H,10,11) |
| InChIKey | KQRCBMPPEPNNDS-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=CC(F)=C1Br |
| CAS DataBase Reference | 132715-69-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-36-22 | |||||||||
| Safety Statements | 26-36/37/39-37 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
2-Bromo-3-fluorobenzoic acid price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B3722 | 2-Bromo-3-fluorobenzoic Acid >96.0%(GC)(T) | 132715-69-6 | 1g | $64 | 2026-03-19 | Buy |
| TCI Chemical | B3722 | 2-Bromo-3-fluorobenzoic Acid >96.0%(GC)(T) | 132715-69-6 | 5g | $198 | 2026-03-19 | Buy |
| Usbiological | 415763 | 2-Bromo-3-fluorobenzoic acid | 132715-69-6 | 100mg | $305 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB38482 | 2-Bromo-3-fluorobenzoic acid | 132715-69-6 | 25g | $200 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB38482 | 2-Bromo-3-fluorobenzoic acid | 132715-69-6 | 50g | $300 | 2021-12-16 | Buy |
2-Bromo-3-fluorobenzoic acid Chemical Properties,Uses,Production
Chemical Properties
Off-white powder
Synthesis Reference(s)
Tetrahedron Letters, 36, p. 881, 1995 DOI: 10.1016/0040-4039(94)02385-O
Synthesis
825-22-9
132715-69-6
The general procedure for the synthesis of 2-bromo-3-fluorobenzoic acid from 2-amino-3-fluorobenzoic acid is as follows: in a 1L three-necked round-bottomed flask equipped with a dropping funnel and a thermometer, 20g (0.13 mol) of 2-amino-3-fluorobenzoic acid and 160mL of acetonitrile were added. After the mixture was cooled to 0 °C, 160 mL of 47% hydrobromic acid solution was added slowly and dropwise over 10 min. Subsequently, a solution prepared from 10 g (0.145 mol) of sodium nitrite (NaNO2) dissolved in 20 mL of water was added dropwise to the reaction system over 1 hour. After the dropwise addition, the reaction mixture was continued to be stirred at 0°C for 5 min. Next, 21.8 g (0.15 mol) of copper bromide (CuBr) was added in batches over 30 minutes. The reaction mixture was transferred to a 70°C oil bath and stirred continuously for 1 hour. Upon completion of the reaction, the mixture was cooled to 0 °C, diluted with 700 mL of water and the precipitate was collected by filtration. The precipitate was washed with cold water and dried under vacuum to give the orange solid product 2-bromo-3-fluorobenzoic acid in a yield of 22 g and 78%.
References
[1] Patent: US2008/293708, 2008, A1. Location in patent: Page/Page column 37
[2] Journal of Heterocyclic Chemistry, 1990, vol. 27, # 7, p. 2151 - 2163
2-Bromo-3-fluorobenzoic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 923 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29822 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2176 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 2-Bromo-3-fluorobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-02 | 2-Bromo-3-fluorobenzoic acid
132715-69-6
|
US $0.10 / KG | 0.1KG | 98% | 200TONS | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-09-02 | 2-Bromo-3-fluorobenzoic acid
132715-69-6
|
US $7.00 / KG | 1KG | 99% | JD 542 | Career Henan Chemical Co |
-
- 2-Bromo-3-fluorobenzoic acid
132715-69-6
- US $0.10 / KG
- 98%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Bromo-3-fluorobenzoic acid
132715-69-6
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
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