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4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE

CAS No.
3767-28-0
Chemical Name:
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
Synonyms
Glc-a-PNP;alfa-PNPG;PNP -α-D-GLU;PNP-ALPHA-GLU;PNP-ALPHA-D-GLC;PNP-α-D-glucopyranoside;p-Nitrophenyl α-glucoside;PNP ALPHA-D-GLUCOPYRANOSIDE;p-Nitrophenol α-D-Glucoside;4-Nitrophenyl a-D-Glucoside
CBNumber:
CB6418148
Molecular Formula:
C12H15NO8
Molecular Weight:
301.25
MDL Number:
MFCD00064088
MOL File:
3767-28-0.mol
MSDS File:
SDS
Last updated:2026-01-13 11:25:30
Product description Number Pack Size Price
p-Nitrophenyl-α-D-glucopyranoside - CAS 3767-28-0 - Calbiochem Chromogenic substrate for α-glucosidase. 487506 1g $56.2
p-Nitrophenyl-α-D-glucopyranoside - CAS 3767-28-0 - Calbiochem Chromogenic substrate for α-glucosidase. 487506 5G $214
4-Nitrophenyl α-D-Glucopyranoside [Substrate for α-D-Glucosidase] >98.0%(HPLC) N0493 1g $47
4-Nitrophenyl α-D-Glucopyranoside [Substrate for α-D-Glucosidase] >98.0%(HPLC) N0493 5g $159
4-Nitrophenyl α-D-glucopyranoside ≥99% N1377 1g $103
More product size

4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE Properties

Melting point 210-216 °C
Boiling point 442.39°C (rough estimate)
Density 1.3709 (rough estimate)
refractive index 218.5 ° (C=0.5, H2O)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: Slightly soluble,PBS (pH 7.2): 0.3 mg/ml
pka 12.55±0.70(Predicted)
form Crystalline Powder
color Off-white to light yellow
Water Solubility Soluble in water, warm ethanol and methanol.
BRN 92212
InChI InChI=1/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11-,12+/s3
InChIKey IFBHRQDFSNCLOZ-ZIQFBCGOSA-N
SMILES O(C1C=CC(N(=O)=O)=CC=1)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |&1:10,12,15,17,19,r|
CAS DataBase Reference 3767-28-0(CAS DataBase Reference)
UNSPSC Code 12352204
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264b-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362+P364-P403+P233-P501c
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
3-10-21
HS Code  29389090
Storage Class 11 - Combustible Solids
NFPA 704
1
1 1

4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 487506 p-Nitrophenyl-α-D-glucopyranoside - CAS 3767-28-0 - Calbiochem Chromogenic substrate for α-glucosidase. 3767-28-0 1g $56.2 2025-07-31 Buy
Sigma-Aldrich 487506 p-Nitrophenyl-α-D-glucopyranoside - CAS 3767-28-0 - Calbiochem Chromogenic substrate for α-glucosidase. 3767-28-0 5G $214 2025-07-31 Buy
TCI Chemical N0493 4-Nitrophenyl α-D-Glucopyranoside [Substrate for α-D-Glucosidase] >98.0%(HPLC) 3767-28-0 1g $47 2025-07-31 Buy
TCI Chemical N0493 4-Nitrophenyl α-D-Glucopyranoside [Substrate for α-D-Glucosidase] >98.0%(HPLC) 3767-28-0 5g $159 2025-07-31 Buy
Sigma-Aldrich N1377 4-Nitrophenyl α-D-glucopyranoside ≥99% 3767-28-0 1g $103 2025-07-31 Buy
Product number Packaging Price Buy
487506 1g $56.2 Buy
487506 5G $214 Buy
N0493 1g $47 Buy
N0493 5g $159 Buy
N1377 1g $103 Buy

4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE Chemical Properties,Uses,Production

Chemical Properties

White Crystals

Uses

Substrate for a-glucosidase inhibitor

Uses

p-Nitrophenyl α-D-Glucopyranoside is a substrate for α-glucosidase inhibitor.

Definition

ChEBI: An alpha-D-glucoside that is beta-D-glucopyranose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.

Biological Activity

4-Nitrophenyl ǥ-D-glucopyranoside serves as a substrate for glycosidases. Upon cleavage, the substrate is converted to a yellow-colored product.

Purification Methods

Purify 4-nitrophenyl--D-glucopyranoside by recrystallisation from H2O, MeOH or EtOH. [Jermyn Aust J Chem 7 202 1954, Montgomery et al. J Am Chem Soc 64 690 1942.] It is a chromogenic substrate from -glucosidases [Oliviera et al. Anal Biochem 1 1 3 1881981], and is a C5227substrate for glucansucrases [Binder & Robyt Carbohydr Research 124 2871983]. [Beilstein 17/7 V 53.]

14131-42-1
3767-28-0
Synthesis of 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE from (4-NITRO)PHENYL-2,3,4,6-TETRA-O-ACETYL-ALPHA-D-GLUCOPYRANOSIDE
Global( 316)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8497 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501 product@acmec-e.com China 33325 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20128 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13799 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21597 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29831 58
Jinan Samuel Pharmaceutical CO., Ltd
0531-88821801 15192360884 605818151@qq.com CHINA 124 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58

View Lastest Price from 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Nitrophenyl α-D-glucopyranoside pictures 2026-02-12 4-Nitrophenyl α-D-glucopyranoside
3767-28-0
US $0.00 / G 5G 98%min 30kg/month WUHAN FORTUNA CHEMICAL CO., LTD
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE pictures 2025-12-01 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
3767-28-0
US $0.00-0.00 / KG 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
	4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE pictures 2025-09-25 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
3767-28-0
US $5.00-0.10 / KG 1KG 98% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-nitrophenylalpha-glucoside P-NITROPHENYL A-D-GLUCOPYRANOSIDE P-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE P-NITROPHENYL-ALPHA-D-GLUCOSIDE PNP-ALPHA-D-GLC PNP ALPHA-D-GLUCOPYRANOSIDE PNP-ALPHA-GLU 4'-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE 4-nitrophenyl -Α-D- glucosaMine pyranoside PNP-α-D-glucopyranoside 4-nitrophenyl alpha-D-glucoside p-Nitrophenyl-α-D-glucopyranoside - CAS 3767-28-0 - Calbiochem Glc-a-PNP a-D-Glucopyranoside, 4-nitrophenyl (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol P-Nitrophenyl-Alpha-D-GlucopyranosideA.R. .alpha.-D-Glucopyranoside, 4-nitrophenyl 4-nitrophenyl-à-d-glucopyranoside 4-Nitrophenyla-D-glucopyranoside p-Nitrophenol α-D-Glucoside 4-Nitrophenyl-ɑ-D-glucopyranoside, 98+% 4-Nitrophenyl alpha-D-Glucopyranoside [Substrate for alpha-D-Glucosidase] 4-Nitrophenyl a-D-Glucoside p-Nitrophenol a-D-Glucoside 4-Nitrophenyl-alpha-D-glucopyranoside, 98+% p-Nitrophenyl α-glucoside 4-Nitrophenyl-^a-D-glucopyranoside, 98+% 4-Nitrophenyl α-D-glucopyranoside,p-Nitrophenyl α-D-glucopyranoside [Substrate for alpha-D-Glucosidase] 4-Nitrophenyl alpha-D-Glucopyranoside  4-Nitrophenyl-alpha-D-glucopyranoside, 99% 1GR 4-Nitrophenyl-alpha-D-glucopyranoside, 99% 5GR 4-Nitrophenyl α-D-Glucopyranoside [Substrate for α-D-Glucosidase] 4-Nitrophenyl-alpha-D-glucopyranoside,99% α-D-Glucopyranoside, 4-nitrophenyl (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-nitrophenoxy)tetrahydropyran-3,4,5-triol 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE USP/EP/BP pNitrophenyl α-Dglucopyranoside 4-Nitrophenyl α-D-glucopyranoside, ≥99% 4-nitrophenyl α-D-glucopyranoside alfa-PNPG 4-Nitrophenyl-α-D-glucopyranosid 4-Nitrophenyl alpha-D-glucosaminide P-nitrobenzene- α- D-glucopyranoside PNP -α-D-GLU 4-nitrophenyl α-D-glucoside (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol 4'-Nitrophenyl-α-D-glucopyranoside 1-O-(4-NITROPHENYL)-ALPHA-D-GLUCOSIDE 4-Nitrophenyl Alpha-D-Pyranoside Glucoside (PNPG) 4-Nitrophenyl α-D-glucopyranoside p-Nitrophenyl-α-D-glucopyranoside 4-Nitrobenzene- Α- D-glucopyranoside 4-Nitrophenyl-alpha-D-glucopyranoside, beta-Anomer < 0.1% 3767-28-0 Sugars Glycosides